Results 11 to 20 of about 229,759 (254)

Quantification of experimentally induced nucleotide conversions in high-throughput sequencing datasets

BMC Bioinformatics, 2019
Background Methods to read out naturally occurring or experimentally introduced nucleic acid modifications are emerging as powerful tools to study dynamic cellular processes.
Tobias Neumann, Veronika A. Herzog, Matthias Muhar, Arndt von Haeseler, Johannes Zuber, Stefan L. Ameres, Philipp Rescheneder   +6 more
doaj   +2 more sources

Precision Medicine Based on High-Throughput Nucleotide Sequencing for a Patient with -Related Developmental Epileptic Encephalopathy [PDF]

Annals of Child Neurology, 2021
Se Eun Park, Dajeong Lee, Joo Young Song, Jeehun Lee, Jiwon Lee   +4 more
doaj   +3 more sources

Selection of optimal bioinformatic tools and proper reference for reducing the alignment error in targeted sequencing data

Journal of Medical Signals and Sensors, 2021
Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi, Mohammad Amin Tabatabaiefar, Mohammadreza Sehhati   +2 more
doaj   +1 more source

Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era [PDF]

Genomics & Informatics, 2013
Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques.
Mincheol Kim, Ki-Hyun Lee, Seok-Whan Yoon, Bong-Soo Kim, Jongsik Chun, Hana Yi   +5 more
doaj   +1 more source

Bacteriome analysis of Aggregatibacter actinomycetemcomitans-JP2 genotype-associated Grade C periodontitis in Moroccan adolescents

Frontiers in Oral Health, 2023
BackgroundGrade C (previously aggressive) periodontitis (GCP) in adolescents is prevalent in certain parts of Africa where it is associated with JP2 genotype, a highly virulent strain of Aggregatibacter actinomycetemcomitans. The aim of this study was to
Vijaya Lakshmi Pavani Molli, Jamila Kissa, Divyashri Baraniya, Amina Gharibi, Tsute Chen, Nezar N. Al-Hebshi, Jasim M. Albandar   +6 more
doaj   +1 more source

Gene expression profile of Scardovia spp. in the metatranscriptome of root caries [PDF]

Brazilian Oral Research, 2020
A few investigations of caries biofilms have identified Scardovia spp.; however, little is known about its involvement in caries pathogenesis. The purpose of this study was to assess the gene expression profile of Scardovia spp.
Naile DAMÉ-TEIXEIRA, Clarissa Cavalcanti Fatturi PAROLO, Marisa MALZ, Deirdre Ann DEVINE, Thuy DO   +4 more
doaj   +2 more sources

Breakthrough Solution for Antimicrobial Resistance Detection: Surface‐Enhanced Raman Spectroscopy‐based on Artificial Intelligence

Advanced Materials Interfaces, EarlyView., 2023
This review discusses the use of Surface‐Enhanced Raman Spectroscopy (SERS) combined with Artificial Intelligence (AI) for detecting antimicrobial resistance (AMR). Various SERS studies used with AI techniques, including machine learning and deep learning, are analyzed for their advantages and limitations.
Zakarya Al‐Shaebi, Munevver Akdeniz, Awel Olsido Ahmed, Mine Altunbek, Omer Aydin   +4 more
wiley   +1 more source

Diagnostics of hereditary cancer syndromes by ngs. A database creation experience [PDF]

Клиническая практика, 2021
Background: More than 500 thousand new cases of malignant neoplasms are registered annually in the Russian Federation, of which more than 50 thousand new cases are due to hereditary forms.
Ivan S. Abramov, Tatyana S. Lisitsa, Anna M. Stroganova, Oxana O. Ryabaya, Anastasiya M. Danishevich, Anastasia O. Khakhina, Anastasiya I. Zakamornaya, Alina D. Matsvay, German A. Shipulin   +8 more
doaj   +1 more source

Optimization of conditions for in vitro modeling of subgingival normobiosis and dysbiosis

Frontiers in Microbiology, 2022
Modeling subgingival microbiome in health and disease is key to identifying the drivers of dysbiosis and to studying microbiome modulation. Here, we optimize growth conditions of our previously described in vitro subgingival microbiome model. Subgingival
Divyashri Baraniya, Thuy Do, Tsute Chen, Jasim M. Albandar, Susan M. Chialastri, Deirdre A. Devine, Philip D. Marsh, Nezar N. Al-Hebshi   +7 more
doaj   +1 more source

On the verge of life: Distribution of nucleotide sequences in viral RNAs [PDF]

Biosemiotics 14, No. 2, 253-269 (2021), 2020
The aim of the study is to analyze viruses using parameters obtained from distributions of nucleotide sequences in the viral RNA. Seeking for the input data homogeneity, we analyze single-stranded RNA viruses only. Two approaches are used to obtain the nucleotide sequences; In the first one, chunks of equal length (four nucleotides) are considered.
arxiv   +1 more source