Uncommon nucleotide excision repair phenotypes revealed by targeted high-throughput sequencing [PDF]
Orphanet Journal of Rare Diseases, 2016 Deficient nucleotide excision repair (NER) activity causes a variety of autosomal recessive diseases including xeroderma pigmentosum (XP) a disorder which pre-disposes to skin cancer, and the severe multisystem condition known as Cockayne syndrome (CS).
Nadège Calmels +28 more
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Targeted Amplicon Sequencing for Single-Nucleotide-Polymorphism Genotyping of Attaching and Effacing Escherichia coli O26:H11 Cattle Strains via a High-Throughput Library Preparation Technique [PDF]
Applied and Environmental Microbiology, 2015 ABSTRACT Enterohemorrhagic Escherichia coli (EHEC) O26:H11, a serotype within Shiga toxin-producing E. coli (STEC) that causes severe human disease, has been considered to have evolved from attaching and effacing E. coli (AEEC) O26:H11 through the acquisition
Sarah A. Ison +8 more
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Microbiome Analysis Using Next-Generation Sequencing in Urinary Tract Infections [PDF]
Urogenital Tract Infection, 2022 In recent decades, the understanding of the genetic information of microbes and hosts has advanced considerably with the development of next-generation sequencing (NGS).
Hyunho Han, Joo Yong Lee
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Journal of Medical Signals and Sensors, 2021 Background: Careful design in the primary steps of a next-generation sequencing study is critical for obtaining successful results in downstream analysis.
Hannane Mohammadi Nodehi +2 more
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Precision Medicine Based on High-Throughput Nucleotide Sequencing for a Patient with SCN2A-Related Developmental Epileptic Encephalopathy [PDF]
Annals of Child Neurology, 2020 Precision Medicine Based on High-Throughput Nucleotide Sequencing for a Patient with SCN2A-Related Developmental Epileptic ...
Se Eun Park +4 more
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Gene expression profile of Scardovia spp. in the metatranscriptome of root caries [PDF]
Brazilian Oral Research, 2020 A few investigations of caries biofilms have identified Scardovia spp.; however, little is known about its involvement in caries pathogenesis. The purpose of this study was to assess the gene expression profile of Scardovia spp.
Naile DAMÉ-TEIXEIRA +4 more
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Analytical Tools and Databases for Metagenomics in the Next-Generation Sequencing Era [PDF]
Genomics & Informatics, 2013 Metagenomics has become one of the indispensable tools in microbial ecology for the last few decades, and a new revolution in metagenomic studies is now about to begin, with the help of recent advances of sequencing techniques.
Mincheol Kim +5 more
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High-throughput single nucleotide polymorphism (SNP) identification and mapping in the sesame (Sesamum indicum L.) genome with genotyping by sequencing (GBS) analysis [PDF]
Molecular Breeding, 2016 Sesame (Sesamum indicum L. syn. Sesamum orientale L.) is considered to be the first oil seed crop known to man. Despite its versatile use as an oil seed and a leafy vegetable, sesame is a neglected crop and has not been a subject of molecular genetic research until the last decade.
Ayşe Özgür Uncu +3 more
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Optimization of conditions for in vitro modeling of subgingival normobiosis and dysbiosis
Frontiers in Microbiology, 2022 Modeling subgingival microbiome in health and disease is key to identifying the drivers of dysbiosis and to studying microbiome modulation. Here, we optimize growth conditions of our previously described in vitro subgingival microbiome model. Subgingival
Divyashri Baraniya +7 more
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