Two-Dimensional and Three-Dimensional Cartilage Model Platforms for Drug Evaluation and High-Throughput Screening Assays. [PDF]
Tissue Eng Part B Rev, 2022 Foster NC, Hall NM, Haj AJE.
europepmc +1 more source
A Split-Luciferase-Based Trimer Formation Assay as a High-throughput Screening Platform for Therapeutics in Alport Syndrome [PDF]
, 2018 Kohei Omachi +13 more
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Identifying and Prioritizing Chemicals with Uncertain Burden of Exposure: Opportunities for Biomonitoring and Health-Related Research. [PDF]
, 2019 BackgroundThe National Institutes of Health's Environmental influences on Child Health Outcomes (ECHO) initiative aims to understand the impact of environmental factors on childhood disease. Over 40,000 chemicals are approved for commercial use.
(Environmental influences on Child Health Outcomes) +9 more
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Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Background There is growing recognition of the potential of plasma proteomics for Alzheimer's Disease (AD) risk assessment and disease characterization. However, differences between proteomics platforms introduce uncertainties regarding cross‐platform applicability.
Manyue Hu +9 more
wiley +1 more source
Composition and applications of focus libraries to phenotypic assays
Frontiers in Pharmacology, 2014 The wealth of bioactivity information now available on low-molecular weight compounds has enabled a paradigm shift in chemical biology and early phase drug discovery efforts.
Anne Mai eWassermann +2 more
doaj +1 more source
Differential Assay for High-Throughput Screening of Antibacterial Compounds
SLAS Discovery, 2007 The previously described Bacillus subtilis reporter strain BAU-102 is capable of detecting cell wall synthesis inhibitors that act at all stages of the cell wall synthesis pathway. In addition, this strain is capable of detecting compounds with hydrophobic/surfactant activity and alternative mechanisms of cell wall disruption.
Shaun P, Falk +2 more
openaire +2 more sources
Multi‐Omics Integration for Advancing Glioma Precision Medicine
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Gliomas are among the most malignant and aggressive tumors of the central nervous system, characterized by the absence of early diagnostic markers, poor prognosis, and a lack of effective treatments. Advances in high‐throughput technologies have facilitated a refined molecular classification of gliomas, incorporating genetic features. However,
Maria Guarnaccia +4 more
wiley +1 more source
High-throughput screening assays for SARS-CoV-2 drug development: Current status and future directions. [PDF]
Drug Discov Today, 2021 Xu T, Zheng W, Huang R.
europepmc +1 more source
An enzyme-coupled high-throughput assay for screening RNA methyltransferase activity inE. Colicell lysate [PDF]
, 2012 Daniela Schulz, Andrea Rentmeister
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