Results 281 to 290 of about 231,965 (320)

High-Throughput Strategies for Streamlining Lipid Nanoparticle Development Pipeline. [PDF]

Adv Sci (Weinh)
Lam L, Watson S, Ramaswamy Y, Singh G.
europepmc   +1 more source

Utilizing the HiBiT System to Identify CARM1 Degraders for Targeted Cancer Therapy. [PDF]

J Med Chem
Bacabac M, Hu M, Liu F, Kim EJ, Grkovic T, Kumar R, Akee RK, Hayes I, Mudududdla R, Wang Y, McGuire M, Tang W, O'Keefe BR, Bugni TS, Xu W.   +14 more
europepmc   +1 more source

Droplet-based single-cell pairing for high-throughput interaction mapping of antigen-receptor combinations. [PDF]

Sci Adv
Nan L, Mao T, Chan CWF, Wang B, Han Z, Choi GCG, Wei X, Wong ASL, Shum HC.   +8 more
europepmc   +1 more source

The Application of Microfluidics in Traditional Chinese Medicine Research. [PDF]

Biosensors (Basel)
Zhu S, Ke X, Li Y, Shu Z, Zheng J, Xue Z, Qi W, Xu B.   +7 more
europepmc   +1 more source

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Acetylcholinesterase Inhibition Assays for High-Throughput Screening

2022
Acetylcholinesterase (AChE) hydrolyzes acetylcholine (ACh), a vital neurotransmitter that regulates muscle movement and brain function, including memory, attention, and learning. Inhibition of AChE activity can cause a variety of adverse health effects and toxicity. Identifying AChE inhibitors quickly and efficiently warrants developing AChE inhibition
Shuaizhang, Li, Andrew J, Li, Jinghua, Zhao, Michael F, Santillo, Menghang, Xia   +4 more
openaire   +2 more sources

Bioluminescent Assays for High-Throughput Screening

ASSAY and Drug Development Technologies, 2007
In the development of high throughput screening (HTS) as a central paradigm of drug discovery, fluorescence has generally been adopted as the favored methodology. Nevertheless, luminescence has maintained a prominent position among certain assay formats, most notably genetic reporters.
Frank, Fan, Keith V, Wood
openaire   +2 more sources

Enzyme assays for high-throughput screening

Current Opinion in Biotechnology, 2004
Assaying enzyme-catalyzed transformations in high-throughput is crucial to enzyme discovery, enzyme engineering and the drug discovery process. In enzyme assays, catalytic activity is detected using labelled substrates or indirect sensor systems that produce a detectable spectroscopic signal upon reaction.
Jean-Philippe, Goddard, Jean-Louis, Reymond   +1 more
openaire   +2 more sources