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High-throughput sequencing: a failure mode analysis [PDF]
BMC Genomics, 2005 Background Basic manufacturing principles are becoming increasingly important in high-throughput sequencing facilities where there is a constant drive to increase quality, increase efficiency, and decrease operating costs.
Marra Marco A +6 more
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High-throughput sequencing in vaccine research [PDF]
Journal of Veterinary Research, 2021 The world of vaccines has changed tremendously since the time of Louis Pasteur. In the present day, it is regarded as vaccinology, a discipline which includes not only the knowledge of vaccine production, strategies for its delivery and influence on the ...
Pasik Katarzyna +1 more
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High‐throughput sequencing for biology and medicine [PDF]
Molecular Systems Biology, 2013 Advances in genome sequencing have progressed at a rapid pace, with increased throughput accompanied by plunging costs. But these advances go far beyond faster and cheaper. High‐throughput sequencing technologies are now routinely being applied to a wide
Wendy Weijia Soon +2 more
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High-throughput sequencing technologies. [PDF]
Molecular Cell, 2015 The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years.
Jason A. Reuter, D. Spacek, M. Snyder
semanticscholar +3 more sources
High-throughput single-сell sequencing in cancer research
Signal Transduction and Targeted Therapy, 2022 With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia +4 more
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Compression of structured high-throughput sequencing data. [PDF]
PLoS ONE, 2013 Large biological datasets are being produced at a rapid pace and create substantial storage challenges, particularly in the domain of high-throughput sequencing (HTS). Most approaches currently used to store HTS data are either unable to quickly adapt to
Fabien Campagne +4 more
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High Throughput Sequencing for Detection of Foodborne Pathogens [PDF]
Frontiers in Microbiology, 2017 High-throughput sequencing (HTS) is becoming the state-of-the-art technology for typing of microbial isolates, especially in clinical samples. Yet, its application is still in its infancy for monitoring and outbreak investigations of foods.
Camilla Sekse +6 more
doaj +4 more sources
Genome reassembly with high-throughput sequencing data [PDF]
BMC Genomics, 2013 Motivation Recent studies in genomics have highlighted the significance of structural variation in determining individual variation. Current methods for identifying structural variation, however, are predominantly focused on either assembling whole ...
Parrish Nathaniel +2 more
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High Throughput Sequencing for Clinical Tuberculosis: An Overview
Pathogens, 2022 High throughput sequencing (HTS) can identify the presence of Mycobacterium tuberculosis DNA in a clinical sample while also providing information on drug susceptibility.
Tara E. Ness +2 more
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Microfluidics applications for high-throughput single cell sequencing
Journal of Nanobiotechnology, 2021 The inherent heterogeneity of individual cells in cell populations plays significant roles in disease development and progression, which is critical for disease diagnosis and treatment.
Wen-min Zhou +10 more
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