Results 11 to 20 of about 1,036,014 (384)

Optimal assembly for high throughput shotgun sequencing [PDF]

BMC Bioinformatics, 2013
We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the repeat statistics of the genome.
Bresler, Guy, Bresler, Ma'ayan, Tse, David   +2 more
openaire   +8 more sources

High-Throughput Microdissection for Next-Generation Sequencing. [PDF]

PLoS ONE, 2016
Precision medicine promises to enhance patient treatment through the use of emerging molecular technologies, including genomics, transcriptomics, and proteomics.
Avi Z Rosenberg, Michael D Armani, Patricia A Fetsch, Liqiang Xi, Tina Thu Pham, Mark Raffeld, Yun Chen, Neil O'Flaherty, Rebecca Stussman, Adele R Blackler, Qiang Du, Jeffrey C Hanson, Mark J Roth, Armando C Filie, Michael H Roh, Michael R Emmert-Buck, Jason D Hipp, Michael A Tangrea   +17 more
doaj   +5 more sources

Universal count correction for high-throughput sequencing.

PLoS Computational Biology, 2014
We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto, Matthew D Edwards, David K Gifford   +2 more
doaj   +7 more sources

High-throughput sequencing of a South American Amerindian. [PDF]

PLoS ONE, 2013
The emergence of next-generation sequencing technologies allowed access to the vast amounts of information that are contained in the human genome. This information has contributed to the understanding of individual and population-based variability and ...
André M Ribeiro-dos-Santos, Jorge Estefano Santana de Souza, Renan Almeida, Dayse O Alencar, Maria Silvanira Barbosa, Leonor Gusmão, Wilson A Silva, Sandro J de Souza, Artur Silva, Ândrea Ribeiro-dos-Santos, Sylvain Darnet, Sidney Santos   +11 more
doaj   +6 more sources

SNP discovery by high-throughput sequencing in soybean [PDF]

BMC Genomics, 2010
Background With the advance of new massively parallel genotyping technologies, quantitative trait loci (QTL) fine mapping and map-based cloning become more achievable in identifying genes for important and complex traits.
Wu Xiaolei, Ren Chengwei, Joshi Trupti, Vuong Tri, Xu Dong, Nguyen Henry T   +5 more
doaj   +3 more sources

Macrophage Changes and High‐Throughput Sequencing in Aging Mouse Intervertebral Disks [PDF]

JOR Spine
Background Intervertebral disk (IVD) degeneration is associated with lower back pain and aging; however, the mechanisms underlying age‐related changes and the changes in macrophage polarization in aging intervertebral disks require further elucidation ...
Wei Wang, Cheng Jiang, Jiong‐Hui Chen, Yong‐Long Chen, Zhen‐Wu Zhang, Zhi‐Chao Yang, Jun Li, Xiao‐Chuan Li   +7 more
doaj   +2 more sources

High Throughput Sequencing and Cancer Genetics [PDF]

Cell Cycle, 2002
Fred Bunz
openalex   +4 more sources

Recent Advances in High Throughput Sequencing Analysis [PDF]

International Journal of Genomics, 2017
Yan Guo, Leng Han, Quanhu Sheng
doaj   +3 more sources

QIIME allows analysis of high-throughput community sequencing data

Nature Methods, 2010
J Gregory Caporaso, Justin Kuczynski, Jesse I Stombaugh   +2 more
exaly   +2 more sources

Analysing high-throughput sequencing data in Python with HTSeq 2.0 [PDF]

Bioinform., 2021
Summary HTSeq 2.0 provides a more extensive application programming interface including a new representation for sparse genomic data, enhancements for htseq-count to suit single-cell omics, a new script for data using cell and molecular barcodes ...
Givanna H. Putri, S. Anders, P. Pyl, J. Pimanda, F. Zanini   +4 more
semanticscholar   +1 more source