Results 21 to 30 of about 766,230 (330)
High-throughput sequencing technologies. [PDF]
Molecular Cell, 2015 The human genome sequence has profoundly altered our understanding of biology, human diversity, and disease. The path from the first draft sequence to our nascent era of personal genomes and genomic medicine has been made possible only because of the extraordinary advancements in DNA sequencing technologies over the past 10 years.
Jason A. Reuter, D. Spacek, M. Snyder
semanticscholar +3 more sources
Recent Advances in High Throughput Sequencing Analysis [PDF]
International Journal of Genomics, 2017 Yan Guo, Leng Han, Quanhu Sheng
doaj +3 more sources
High-throughput Phenotyping with Temporal Sequences [PDF]
Journal of the American Medical Informatics Association, 2019 ABSTRACTObjectiveHigh-throughput electronic phenotyping algorithms can accelerate translational research using data from electronic health record (EHR) systems. The temporal information buried in EHRs are often underutilized in developing computational phenotypic definitions.
Alyssa P. Goodson +5 more
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Nature Communications, 2023 Long-read single-cell RNA isoform sequencing can elucidate the intricate landscape of alternative RNA splicing in individual cells, but it suffers from a low read throughput.
Zhuoxing Shi +11 more
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High Throughput Sequencing: An Overview of Sequencing Chemistry [PDF]
Indian Journal of Microbiology, 2016 In the present century sequencing is to the DNA science, what gel electrophoresis was to it in the last century. From 1977 to 2016 three generation of the sequencing technologies of various types have been developed. Second and third generation sequencing technologies referred commonly to as next generation sequencing technology, has evolved ...
Deepika Trakroo +4 more
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High‐Throughput
Molecular Ecology, 2018 AbstractReconstructing the colonization and demographic dynamics that gave rise to extant forests is essential to forecasts of forest responses to environmental changes. Classical approaches to map how population of trees changed through space and time largely rely on pollen distribution patterns, with only a limited number of studies exploiting DNA ...
Marianne Ramstein +37 more
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HTSlib: C library for reading/writing high-throughput sequencing data
GigaScience, 2021 Background Since the original publication of the VCF and SAM formats, an explosion of software tools have been created to process these data files. To facilitate this a library was produced out of the original SAMtools implementation, with a focus on ...
J. Bonfield +7 more
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High‐throughput sequencing of the melanoma genome [PDF]
Experimental Dermatology, 2012 AbstractNext‐generation sequencing technologies are now common for whole‐genome, whole‐exome and whole‐transcriptome sequencing (RNA‐seq) of tumors to identify point mutations, structural or copy number alterations and changes in gene expression. A substantial number of studies have already been performed for melanoma. One study analysed eight melanoma
Manfred Kunz +2 more
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BOOGIE: Predicting Blood Groups from High Throughput Sequencing Data. [PDF]
PLoS ONE, 2015 Over the last decade, we have witnessed an incredible growth in the amount of available genotype data due to high throughput sequencing (HTS) techniques.
Manuel Giollo +5 more
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Rapid genotyping of soybean cultivars using high throughput sequencing. [PDF]
PLoS ONE, 2011 Soybean (Glycine max) breeding involves improving commercially grown varieties by introgressing important agronomic traits from poor yielding accessions and/or wild relatives of soybean while minimizing the associated yield drag.
Kranthi Varala +3 more
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