Results 31 to 40 of about 308,924 (265)
Journal of Inflammation Research, 2021 Hui Jiang1,2 *,* Kefeng Cao3 *,* Chang Fan,1,2 Xiaoya Cui,1,2 Yanzhen Ma,1,2 Jian Liu1 1Experimental Center of Clinical Research, First Affiliated Hospital of Anhui University of Chinese Medicine, Hefei, Anhui, People’s Republic of China; 2School ...
Jiang H +5 more
doaj
Universal count correction for high-throughput sequencing.
PLoS Computational Biology, 2014 We show that existing RNA-seq, DNase-seq, and ChIP-seq data exhibit overdispersed per-base read count distributions that are not matched to existing computational method assumptions.
Tatsunori B Hashimoto +2 more
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ReSeq simulates realistic Illumina high-throughput sequencing data
Genome Biology, 2021 In high-throughput sequencing data, performance comparisons between computational tools are essential for making informed decisions at each step of a project.
Stephan Schmeing, Mark D. Robinson
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Optimal assembly for high throughput shotgun sequencing [PDF]
BMC Bioinformatics, 2013 We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the repeat statistics of the genome.
Bresler, Guy +2 more
openaire +5 more sources
Scrutinizing virus genome termini by high-throughput sequencing. [PDF]
PLoS ONE, 2014 Analysis of genomic terminal sequences has been a major step in studies on viral DNA replication and packaging mechanisms. However, traditional methods to study genome termini are challenging due to the time-consuming protocols and their inefficiency ...
Shasha Li +6 more
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High-throughput sequencing: a failure mode analysis
BMC Genomics, 2005 Background Basic manufacturing principles are becoming increasingly important in high-throughput sequencing facilities where there is a constant drive to increase quality, increase efficiency, and decrease operating costs.
Marra Marco A +6 more
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Efficient COI barcoding using high throughput single-end 400 bp sequencing
BMC Genomics, 2020 Background Over the last decade, the rapid development of high-throughput sequencing platforms has accelerated species description and assisted morphological classification through DNA barcoding. However, the current high-throughput DNA barcoding methods
Chentao Yang +14 more
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Organoids in pediatric cancer research
FEBS Letters, EarlyView.Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Robust Sub-nanomolar Library Preparation for High Throughput Next Generation Sequencing
BMC Genomics, 2018 Background Current library preparation protocols for Illumina HiSeq and MiSeq DNA sequencers require ≥2 nM initial library for subsequent loading of denatured cDNA onto flow cells.
Wells W. Wu +7 more
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Microfluidics applications for high-throughput single cell sequencing
Journal of Nanobiotechnology, 2021 The inherent heterogeneity of individual cells in cell populations plays significant roles in disease development and progression, which is critical for disease diagnosis and treatment.
Wen-min Zhou +10 more
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