Results 51 to 60 of about 17,221,339 (259)

Binocular interaction: contrast matching and contrast discrimination are predicted by the same model [PDF]

, 2007
How do signals from the 2 eyes combine and interact? Our recent work has challenged earlier schemes in which monocular contrast signals are subject to square-law transduction followed by summation across eyes and binocular gain control.
Tim S. Meese, Georgeson, Mark A., Georgeson, Mark A, Mark A. Georgeson, Baker, D.H., Meese, T.S., Baker, Daniel H, Georgeson, M.A., Meese, Timothy S., Baker, Daniel H., Meese, Tim S, Daniel H. Baker   +11 more
core   +1 more source

Structural and biochemical analysis of a B12 superbinder

FEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices, Jacob J. Whittaker, Dirk J. Slotboom, Albert Guskov   +3 more
wiley   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

FEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav, Bogdan I. Florea, Sebastian Geibel   +2 more
wiley   +1 more source

JWST-TST High Contrast: Achieving Direct Spectroscopy of Faint Substellar Companions Next to Bright Stars with the NIRSpec Integral Field Unit

The Astronomical Journal
The JWST NIRSpec integral field unit (IFU) presents a unique opportunity to observe directly imaged exoplanets from 3 to 5 μ m at moderate spectral resolution ( R ∼ 2700) and thereby better constrain the composition, disequilibrium chemistry, and cloud ...
Jean-Baptiste Ruffio, Marshall D. Perrin, Kielan K. W. Hoch, Jens Kammerer, Quinn M. Konopacky, Laurent Pueyo, Alex Madurowicz, Emily Rickman, Christopher A. Theissen, Shubh Agrawal, Alexandra Z. Greenbaum, Brittany E. Miles, Travis S. Barman, William O. Balmer, Jorge Llop-Sayson, Julien H. Girard, Isabel Rebollido, Rémi Soummer, Natalie H. Allen, Jay Anderson, Charles A. Beichman, Andrea Bellini, Geoffrey Bryden, Néstor Espinoza, Ana Glidden, Jingcheng Huang, Nikole K. Lewis, Mattia Libralato, Dana R. Louie, Sangmo Tony Sohn, Sara Seager, Roeland P. van der Marel, Hannah R. Wakeford, Laura L. Watkins, Marie Ygouf, C. Matt Mountain   +35 more
doaj   +1 more source

Apparent diffusion coefficient and Magnetic resonance spectroscopy in grading of malignant brain neoplasms

The Egyptian Journal of Radiology and Nuclear Medicine, 2014
Aim: This work aims to study the role of combined apparent diffusion coefficient (ADC) and Magnetic resonance spectroscopy (MRS) in grading malignant brain neoplasms.
Mahmoud Abd Elaziz Dawoud, Mohamed Fouad Sherif, Mohamed Adel Eltomey   +2 more
doaj   +1 more source

Conventions, symbols, quantities, units and constants for high-resolution molecular spectroscopy

, 2011
A summary of conventions, symbols, quantities, units, and constants which are important for high‐resolution molecular spectroscopy is provided. In particular, great care is taken to provide definitions which are consistent with the recommendations of the
Jürgen Stohner, Martin Quack, Stohner, Jürgen, Quack, Martin   +3 more
core   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

FEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge, Vivian Pogenberg, Alexander Baumgart, Bente Siebels, Hartmut Schlüter, Michael Hecht‐Bucher, Aymelt Itzen   +6 more
wiley   +1 more source

Atmospheric Abundances and Bulk Properties of the Binary Brown Dwarf Gliese 229Bab from JWST/MIRI Spectroscopy

The Astrophysical Journal Letters
We present JWST/Mid Infrared Instrument (MIRI) low-resolution spectroscopy (4.75–14 μ m) of the first known substellar companion, Gliese 229Bab, which was recently resolved into a tight binary brown dwarf.
Jerry W. Xuan, Marshall D. Perrin, Dimitri Mawet, Heather A. Knutson, Sagnick Mukherjee, Yapeng Zhang, Kielan K. W. Hoch, Jason J. Wang, Julie Inglis, Nicole L. Wallack, Jean-Baptiste Ruffio   +10 more
doaj   +1 more source

High-speed tissue metabolism measurement using a combination of diffuse speckle contrast analysis and near-infrared spectroscopy

International Journal of Optomechatronics
This study presents and validates a multimodal optical system combining diffuse speckle contrast analysis (DSCA) and near-infrared spectroscopy (NIRS) with a unique system design for high-speed tMRO2 monitoring.
Chaebeom Yeo, Yeonhee Chang, Cheol Song
doaj   +1 more source

Smaller is better: nanobodies meet NMR

FEBS Letters, EarlyView.
Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley   +1 more source