Results 81 to 90 of about 17,221,339 (259)
Molecular Oncology, EarlyView.Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani +9 more
wiley +1 more source
Discovery of an Exterior Third Planet Orbiting β Pictoris
The Astrophysical Journal LettersWe report the discovery of β Pictoris d ( β Pic d), a third giant planet in the β Pictoris system, which now becomes only the second directly imaged system with more than two confirmed planets.
Aidan Gibbs +11 more
doaj +1 more source
Vickers Hardness of Diamond and cBN Single Crystals: AFM Approach
Crystals, 2017 Atomic force microscopy in different operation modes (topography, derivative topography, and phase contrast) was used to obtain 3D images of Vickers indents on the surface of diamond and cBN single crystals with high spatial resolution.
Sergey Dub +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault +12 more
wiley +1 more source
The Exozodi Spectral Effect: Residual Habitable Zone Dust May Bias exoEarth Characterization
The Astronomical JournalAll exoplanetary systems are expected to host exozodiacal dust, or exozodi, originating from planetesimals. For many stars, exozodi will likely be the largest source of astrophysical noise in direct observations of terrestrial exoplanets. Nearby Sun-like
Miles H. Currie +3 more
doaj +1 more source
Characterization of a Cyclic Nucleotide-Activated K+ Channel and its Lipid Environment by Using Solid-State NMR Spectroscopy [PDF]
, 2013 Voltage-gated ion channels are large tetrameric multidomain membrane proteins that play crucial roles in various cellular transduction pathways. Because of their large size and domain-related mobility, structural characterization has proved challenging ...
NMR Spectroscopy +3 more
core +1 more source
Molecular Oncology, EarlyView.Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu +9 more
wiley +1 more source
Molecular Brain, 2018 Higher dietary intakes of saturated fatty acid increase the risk of developing Alzheimer’s disease and dementia, and even in people without diabetes higher glucose levels may be a risk factor for dementia.
Young-Suk Choi +12 more
doaj +1 more source
Molecular Oncology, EarlyView.The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
Selective Membrane Transport Systems studied by Solid-State NMR Spectroscopy [PDF]
, 2009 Membranes border cells from their environment. Thus, they belong to the basic prerequisites for life as we know it. Within cells, membranes are used to establish compartments dedicated to specific tasks such as providing local proximity of components ...
Ader, C. +3 more
core +1 more source