Results 51 to 60 of about 1,474,036 (268)

Waveguide-mode interference lithography technique for high contrast subwavelength structures in the visible region

Optics Express, 2014
We explore possibilities of waveguide-mode interference lithography (WMIL) technique for high contrast subwavelength structures in the visible region. Selecting an appropriate waveguide-mode, we demonstrate high contrast resist mask patterns for the first time.
K. Kusaka, H. Kurosawa, S. Ohno, Y. Sakaki, K. Nakayama, Y. Moritake, T. Ishihara   +6 more
openaire   +3 more sources

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

JWST/NIRCam Detection of the Fomalhaut C Debris Disk in Scattered Light

The Astrophysical Journal Letters
Observations of debris disks offer important insights into the formation and evolution of planetary systems. Though M dwarfs make up approximately 80% of nearby stars, very few M dwarf debris disks have been studied in detail—making it unclear how or if ...
Kellen Lawson, Joshua E. Schlieder, Jarron M. Leisenring, Ell Bogat, Charles A. Beichman, Geoffrey Bryden, András Gáspár, Tyler D. Groff, Michael W. McElwain, Michael R. Meyer, Thomas Barclay, Per Calissendorff, Matthew De Furio, Yiting Li, Marcia J. Rieke, Marie Ygouf, Thomas P. Greene, Julien H. Girard, Mario Gennaro, Jens Kammerer, Armin Rest, Thomas L. Roellig, Ben Sunnquist   +22 more
doaj   +1 more source

Nonlinear temporal pulse cleaning techniques and application

High Power Laser Science and Engineering, 2013
Two different pulse cleaning techniques for ultra-high contrast laser systems are comparably analysed in this work. The first pulse cleaning technique is based on noncollinear femtosecond optical-parametric amplification (NOPA) and second-harmonic ...
Yi Xu, Jianzhou Wang, Yansui Huang, Yanyan Li, Xiaomin Lu, Yuxin Leng   +5 more
doaj   +1 more source

Liver organoids: modelling complexity in homeostasis and disease

FEBS Letters, EarlyView.
Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley   +1 more source

OASIS Survey Direct Imaging and Astrometric Discovery of HIP 71618 B: A Substellar Companion Suitable for the Roman Coronagraph Technology Demonstration

The Astrophysical Journal Letters
We present the OASIS survey program discovery of a substellar companion orbiting the young A1V star HIP 71618, detected using precision astrometry from Gaia and Hipparcos and high-contrast imaging with SCExAO/CHARIS and Keck/NIRC2.
Mona El Morsy, Thayne Currie, Brianna Lacy, Taylor L. Tobin, Qier An, Yiting Li, Ziying Gu, Masayuki Kuzuhara, Danielle Bovie, Dillon Peng, Jeffrey Chilcote, Olivier Guyon, Miles Lucas, Timothy D. Brandt, Robert de Rosa, Tyler D. Groff, Markus Janson, N. J. Kasdin, Julien Lozi, Christian Marois, Bertrand Mennesson, Naoshi Murakami, Eric Nielsen, Sabina Sagynbayeva, Nour Skaf, William Thompson, Motohide Tamura, Taichi Uyama, Alice Zurlo, Vincent Deo, Sebastien Vievard   +30 more
doaj   +1 more source

High-Contrast Fluorescence Microscopy for a Biomolecular Analysis Based on Polarization Techniques Using an Optical Interference Mirror Slide

Biosensors, 2014
Fluorescence microscopy with an improved contrast for fluorescence images is developed using an optical interference mirror (OIM) slide, which can enhance the fluorescence from a fluorophore as a result of the double interference of the excitation light ...
Mitsuru Yasuda, Takuo Akimoto
doaj   +1 more source

The microbiome in human skin aging

FEBS Letters, EarlyView.
Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana, Cornelia Wiegand, Omid Omrani, Mario Fabri   +3 more
wiley   +1 more source

Direct Imaging Discovery of Giant Exoplanet β Pictoris d: A Decade-long Game of Hide-and-seek

The Astrophysical Journal Letters
We report the direct imaging discovery of a third exoplanet in the β  Pictoris ( β Pic) system. We detect β  Pictoris d ( β Pic d) in noncoronagraphic observations obtained with the Very Large Telescope (VLT) Enhanced Resolution Imager and Spectrograph ...
Ben J. Sutlieff, Markus J. Bonse, Valentin Christiaens, Clémence Fontanive, Elisabeth C. Matthews, Luke T. Parker, Tim D. Pearce, Jayne L. Birkby, Beth A. Biller, Trent J. Dupuy, Emily O. Garvin, Leyla Iskandarli, Jens Kammerer, Yifan Zhou, Robert J. De Rosa, Aarynn L. Carter, Sasha Hinkley, Matthew A. Kenworthy, William O. Balmer, Iain Hammond, James Mang, Caroline V. Morley, Mark J. Neeser, Olivier Absil, Anthony Boccaletti, Mariangela Bonavita, Brendan P. Bowler, Xueqing Chen, Felix A. Dannert, Julien H. Girard, Markus Kasper, Anne-Marie Lagrange, Pengyu Liu, Gilles Orban de Xivry, Michael Poon, Sascha P. Quanz, Benoît Serra, Johanna M. Vos, Kevin Wagner, Jason Wang, Bernhard Schölkopf, Guido Agapito, Alex Agudo Berbel, Dániel Apai, Andrea Baruffolo, Martin Black, Marco Bonaglia, Runa Briguglio, Yixian Cao, Luca Carbonaro, Lee Chapman, Giovanni Cresci, Yigit Dallilar, Richard Davies, Matthias Deysenroth, Ivan Di Antonio, Amico Di Cianno, Gianluca Di Rico, David Doelman, Mauro Dolci, Frank Eisenhauer, Simone Esposito, Debora Ferruzzi, Helmut Feuchtgruber, Natascha Förster-Schreiber, Kyle Franson, Reinhard Genzel, Stefan Gillessen, Eileen C. Gonzales, Michael Hartl, Jean Hayoz, Heinrich Huber, Christoph Keller, Kateryna Kravchenko, Jarron Leisenring, John Lightfoot, David Lunney, Dieter Lutz, Mike Macintosh, Filippo Mannucci, Stanimir Metchev, Thomas Ott, David Pearson, Alfio Puglisi, Sebastian Rabien, Christian Rau, Armando Riccardi, Bernardo Salasnich, Taro Shimizu, Frans Snik, Eckhard Sturm, Genaro Suárez, Linda Tacconi, Xianyu Tan, William Taylor, Christopher Waring, Marco Xompero   +96 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source