Results 71 to 80 of about 3,896,846 (293)

JWST/NIRCam Detection of the Fomalhaut C Debris Disk in Scattered Light

The Astrophysical Journal Letters
Observations of debris disks offer important insights into the formation and evolution of planetary systems. Though M dwarfs make up approximately 80% of nearby stars, very few M dwarf debris disks have been studied in detail—making it unclear how or if ...
Kellen Lawson, Joshua E. Schlieder, Jarron M. Leisenring, Ell Bogat, Charles A. Beichman, Geoffrey Bryden, András Gáspár, Tyler D. Groff, Michael W. McElwain, Michael R. Meyer, Thomas Barclay, Per Calissendorff, Matthew De Furio, Yiting Li, Marcia J. Rieke, Marie Ygouf, Thomas P. Greene, Julien H. Girard, Mario Gennaro, Jens Kammerer, Armin Rest, Thomas L. Roellig, Ben Sunnquist   +22 more
doaj   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

OASIS Survey Direct Imaging and Astrometric Discovery of HIP 71618 B: A Substellar Companion Suitable for the Roman Coronagraph Technology Demonstration

The Astrophysical Journal Letters
We present the OASIS survey program discovery of a substellar companion orbiting the young A1V star HIP 71618, detected using precision astrometry from Gaia and Hipparcos and high-contrast imaging with SCExAO/CHARIS and Keck/NIRC2.
Mona El Morsy, Thayne Currie, Brianna Lacy, Taylor L. Tobin, Qier An, Yiting Li, Ziying Gu, Masayuki Kuzuhara, Danielle Bovie, Dillon Peng, Jeffrey Chilcote, Olivier Guyon, Miles Lucas, Timothy D. Brandt, Robert de Rosa, Tyler D. Groff, Markus Janson, N. J. Kasdin, Julien Lozi, Christian Marois, Bertrand Mennesson, Naoshi Murakami, Eric Nielsen, Sabina Sagynbayeva, Nour Skaf, William Thompson, Motohide Tamura, Taichi Uyama, Alice Zurlo, Vincent Deo, Sebastien Vievard   +30 more
doaj   +1 more source

Norm-resolvent convergence of one-dimensional high-contrast periodic problems to a Kronig-Penney dipole-type model

, 2015
We prove operator-norm resolvent convergence estimates for one-dimensional periodic differential operators with rapidly oscillating coefficients in the non-uniformly elliptic high-contrast setting, which has been out of reach of the existing ...
Cherednichenko, Kirill D., Kiselev, Alexander V.   +1 more
core   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

The JWST Early Release Science Program for Direct Observations of Exoplanetary Systems. IV. NIRISS Aperture Masking Interferometry Performance and Lessons Learned

The Astrophysical Journal Letters
We present a performance analysis for the aperture masking interferometry (AMI) mode on board the James Webb Space Telescope Near Infrared Imager and Slitless Spectrograph (JWST/NIRISS).
Steph Sallum, Shrishmoy Ray, Jens Kammerer, Anand Sivaramakrishnan, Rachel Cooper, Alexandra Z. Greebaum, Deepashri Thatte, Matthew De Furio, Samuel M. Factor, Michael R. Meyer, Jordan M. Stone, Aarynn Carter, Beth Biller, Sasha Hinkley, Andrew Skemer, Genaro Suárez, Jarron M. Leisenring, Marshall D. Perrin, Adam L. Kraus, Olivier Absil, William O. Balmer, Sarah K. Betti, Anthony Boccaletti, Mariangela Bonavita, Mickael Bonnefoy, Mark Booth, Brendan P. Bowler, Zackery W. Briesemeister, Marta L. Bryan, Per Calissendorff, Faustine Cantalloube, Gael Chauvin, Christine H. Chen, Elodie Choquet, Valentin Christiaens, Gabriele Cugno, Thayne Currie, Camilla Danielski, Trent J. Dupuy, Jacqueline K. Faherty, Michael P. Fitzgerald, Jonathan J. Fortney, Kyle Franson, Julien H. Girard, Carol A. Grady, Eileen C. Gonzales, Thomas Henning, Dean C. Hines, Kielan K. W. Hoch, Callie E. Hood, Alex R. Howe, Markus Janson, Paul Kalas, Grant M. Kennedy, Matthew A. Kenworthy, Pierre Kervella, Daniel Kitzmann, Masayuki Kuzuhara, Anne-Marie Lagrange, Pierre-Olivier Lagage, Kellen Lawson, Cecilia Lazzoni, Ben W. P. Lew, Michael C. Liu, Pengyu Liu, Jorge Llop-Sayson, James P. Lloyd, Anna Lueber, Bruce Macintosh, Elena Manjavacas, Sebastian Marino, Mark S. Marley, Christian Marois, Raquel A. Martinez, Brenda C. Matthews, Elisabeth C. Matthews, Dimitri Mawet, Johan Mazoyer, Michael W. McElwain, Stanimir Metchev, Brittany E. Miles, Maxwell A. Millar-Blanchaer, Paul Molliere, Sarah E. Moran, Caroline V. Morley, Sagnick Mukherjee, Paulina Palma-Bifani, Eric Pantin, Polychronis Patapis, Simon Petrus, Laurent Pueyo, Sascha P. Quanz, Andreas Quirrenbach, Isabel Rebollido, Jea Adams Redai, Bin B. Ren, Emily Rickman, Matthias Samland, B. A. Sargent, Joshua E. Schlieder, Glenn Schneider, Karl R. Stapelfeldt, Ben J. Sutlieff, Motohide Tamura, Xianyu Tan, Christopher A. Theissen, Taichi Uyama, Arthur Vigan, Malavika Vasist, Johanna M. Vos, Kevin Wagner, Jason J. Wang, Kimberly Ward-Duong, Niall Whiteford, Schuyler G. Wolff, Kadin Worthen, Mark C. Wyatt, Marie Ygouf, Xi Zhang, Keming Zhang, Zhoujian Zhang, Yifan Zhou, Alice Zurlo   +122 more
doaj   +1 more source

MRI in Menière’s Disease

Journal of the Belgian Society of Radiology, 2018
The visualization of the morphologic substrate of Menière’s disease -the endolymphatic hydrops – can be performed using non-contrast as well as contrast-enhanced magnetic resonance imaging techniques. The non-contrast magnetic resonance imaging technique
Anja Bernaerts
doaj   +1 more source

Simulated X-ray Spectra From Ionized Wind-Blown Nebulae around Massive Stars

, 2012
Using an ionization gasdynamics code, we simulate a model of the wind-blown bubble around a 40 solar mass star. We use this to compute the X-ray spectra from the bubble, which can be directly compared to observations.
Anders, Arthur, Arthur, Chu, Chu, D.L. Rosenberg, Dewey, Dwarkadas, Dwarkadas, Dwarkadas, Dwarkadas, Dwarkadas, Dwarkadas, Freyer, Freyer, Garcia-Segura, Garcia-Segura, Houck, Toalá, V.V. Dwarkadas, van Marle, van Marle, van Marle, Weaver, Whalen, Wrigge, Zhekov   +26 more
core   +1 more source

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source