Results 81 to 90 of about 1,420,424 (313)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
V960 Mon is an FU Orionis object that shows strong evidence of a gravitationally unstable spiral arm that is fragmenting into several dust clumps. We report the discovery of a new substellar companion candidate around this young star, identified in high ...
Anuroop Dasgupta +10 more
doaj +1 more source
Alignment of contrast enhanced medical images
The re-alignment of series of medical images in which there are multiple contrast variations is difficult. The reason for this is that the popularmeasures of image similarity used to drive the alignment procedure do not separate the influence of ...
Melbourne, A.
core
Biophysical approaches for studying viral entry
Viruses infect all living organisms and have been responsible for major epidemics and pandemics. Their ongoing evolutionary battle with host defenses creates a constant need for improved tools to study viral behavior. Advancing methods to probe viral attachment, fusion, and genome release deepen our understanding of how infections begin and support the
Inbar Yosibash, Raya Sorkin
wiley +1 more source
The presence of infrared excesses around stars directly correlates with spatially resolved imaging detections of circumstellar disks at both millimeter and optical/near-infrared wavelengths.
Justin Hom +10 more
doaj +1 more source
MR Neurography: Current Several Issues for Novice Radiologists
Magnetic resonance neurography (MRN) has been increasingly used in recent years for the assessment of peripheral neuropathies. Fat suppression T2-weighted imaging (T2WI) and diffusion- weighted imaging (DWI) have typically been used to provide high ...
Dong-ho Ha
doaj +1 more source
An Adaptive and Non-Linear Technique for Enhancement of High Contrast Images
In night time surveillance, there is a possibility of having extremely bright and dark regions in some image frames of a video sequence. Neither the object details in the low intensity areas nor in the high intensity areas can be clearly interpreted. Several image processing techniques have been developed to retrieve meaningful information under low ...
openaire +2 more sources
Single Photon Counting X Ray Micro Imaging of Biological Samples
In this thesis, performed in the framework of the interdisciplinary research of the Italian National Institute of Physics (INFN) and within a collaboration with Prof. S.
Frallicciardi, Paola Maria
core
Cellular tracking and mitosis detection in dense in-vitro cellular data [PDF]
Cell migration and cell division are two key processes that are associated with a wide range of biological phenomena including embryogenesis, inflammation, wound healing, tumour development etc.
Thirusittampalam, Ketheesan
core
The human gut microbiome across the life course
Despite significant individual variation and continuous change throughout life, the human gut microbiome follows some life stage‐specific trends. This article provides a brief overview of how gut microbiome composition shifts across different phases of life. Created in BioRender. Özkurt, E. (2026) https://BioRender.com/8q4nrnc.
Alise J. Ponsero +4 more
wiley +1 more source

