Results 81 to 90 of about 21,693,337 (313)
The Astrophysical Journal LettersWe present the OASIS survey program discovery of a substellar companion orbiting the young A1V star HIP 71618, detected using precision astrometry from Gaia and Hipparcos and high-contrast imaging with SCExAO/CHARIS and Keck/NIRC2.
Mona El Morsy +30 more
doaj +1 more source
Biosensors, 2014 Fluorescence microscopy with an improved contrast for fluorescence images is developed using an optical interference mirror (OIM) slide, which can enhance the fluorescence from a fluorophore as a result of the double interference of the excitation light ...
Mitsuru Yasuda, Takuo Akimoto
doaj +1 more source
Marathon adaptation to spatial contrast: Saturation in sight [PDF]
, 1985 The contrast thresholds for detecting a 6.0 c/deg vertical sinusoidal test grating were tracked during and after 3 hr inspection of a high-contrast adapting grating of the same spatial frequency and orientation.
Magnussen, S., Greenlee, Mark W.
core +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source
Direct Imaging Discovery of Giant Exoplanet β Pictoris d: A Decade-long Game of Hide-and-seek
The Astrophysical Journal LettersWe report the direct imaging discovery of a third exoplanet in the β Pictoris ( β Pic) system. We detect β Pictoris d ( β Pic d) in noncoronagraphic observations obtained with the Very Large Telescope (VLT) Enhanced Resolution Imager and Spectrograph ...
Ben J. Sutlieff +96 more
doaj +1 more source
Bringing mirrors to rest: Grating concepts for ultra-precise interferometry
, 2022 Paper 93720F, 6 S.Experiments in the field of high precision metrology such as the detection of gravitational waves are crucially limited by the thermal fluctuations of the optical components.
Kley, Ernst Bernhard +2 more
core +1 more source
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Contrast threshold elevation following continuous and interrupted adaptation [PDF]
, 1986 Contrast thresholds for a 6 c/deg sinewave grating were measured following continuous and interrupted adaptation of 10 min duration to a high-contrast (0.6) sinewave grating of the same spatial frequency. Interrupted adaptation was administered as five 2-
Magnussen, S., Greenlee, Mark W.
core +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
The Astrophysical Journal LettersWe present a performance analysis for the aperture masking interferometry (AMI) mode on board the James Webb Space Telescope Near Infrared Imager and Slitless Spectrograph (JWST/NIRISS).
Steph Sallum +122 more
doaj +1 more source