Results 91 to 100 of about 21,693,337 (313)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

The JWST Early Release Science Program for Direct Observations of Exoplanetary Systems. III. Aperture Masking Interferometric Observations of the Star HIP 65426 at 3.8 μm

open access: yesThe Astrophysical Journal Letters
We present aperture masking interferometry (AMI) observations of the star HIP 65426 at 3.8 μ m, as part of the JWST Direct Imaging Early Release Science program, obtained using the Near Infrared Imager and Slitless Spectrograph instrument.
Shrishmoy Ray   +125 more
doaj   +1 more source

An Adaptive and Non-Linear Technique for Enhancement of High Contrast Images

open access: yes, 2007
In night time surveillance, there is a possibility of having extremely bright and dark regions in some image frames of a video sequence. Neither the object details in the low intensity areas nor in the high intensity areas can be clearly interpreted. Several image processing techniques have been developed to retrieve meaningful information under low ...
openaire   +2 more sources

High contrast and low contrast visual acuity in age related macular degeneration

open access: yes, 1989
Low contrast Bailey-Lovie visual acuity (LCBL) and high contrast Bailey-Lovie visual acuity (HCBL) were measured in subjects with age-related macular degeneration (ARM) and subjects with normal visual function.
Lovie-Kitchin, Jan E.
core  

Discerning protein pools by selective staining with self‐labeling tags

open access: yesFEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source

VLT/ERIS Observations of the V960 Mon System: A Dust-embedded Substellar Object Formed by Gravitational Instability?

open access: yesThe Astrophysical Journal Letters
V960 Mon is an FU Orionis object that shows strong evidence of a gravitationally unstable spiral arm that is fragmenting into several dust clumps. We report the discovery of a new substellar companion candidate around this young star, identified in high ...
Anuroop Dasgupta   +10 more
doaj   +1 more source

MRI in Menière’s Disease

open access: yesJournal of the Belgian Society of Radiology, 2018
The visualization of the morphologic substrate of Menière’s disease -the endolymphatic hydrops – can be performed using non-contrast as well as contrast-enhanced magnetic resonance imaging techniques. The non-contrast magnetic resonance imaging technique
Anja Bernaerts
doaj   +1 more source

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

The Disks In Scorpius–Centaurus Survey (DISCS). I. Four Newly Resolved Debris Disks in Polarized Intensity Light

open access: yesThe Astronomical Journal
The presence of infrared excesses around stars directly correlates with spatially resolved imaging detections of circumstellar disks at both millimeter and optical/near-infrared wavelengths.
Justin Hom   +10 more
doaj   +1 more source

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

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