Results 111 to 120 of about 3,896,846 (293)
A MIRI Search for Planets and Dust around WD 2149+021
The Astronomical JournalThe launch of JWST has ushered in a new era of high-precision infrared astronomy, allowing us to probe nearby white dwarfs for cold dust, exoplanets, and tidally heated exomoons.
Sabrina Poulsen +11 more
doaj +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
A Scatter of Light from a Polarized World
The Astronomical JournalMany known exoplanets harbor clouds, which lead to degeneracies in spectroscopic models between particle composition and size. Polarimetry, however, provides independent assessment.
Sloane J. Wiktorowicz +3 more
doaj +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Molecular Oncology, EarlyView.Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
Linear Polarization Variations and Circular Polarization Are Common among Airless Bodies
The Planetary Science JournalUsing the POLISH2 polarimeter at the Lick Observatory Shane 3 m and Nickel 1 m telescopes, we discover rotation-phase-locked variations in linear polarization to be common among asteroids and a near-Earth object (NEO) in a clear, 383−720 nm bandpass ...
Sloane J. Wiktorowicz +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Numerical Technique for Electromagnetic Field Computation Including High Contrast Composite Material
, 2012 Periodic structure plays important role with its sensitivity for frequency in microwave communication and optical integrated circuit system [1][2]. Also, in optical fiber communication[3], such periodic structure is used for supporting optical wave to be guided in core of the fiber.
openaire +3 more sources
Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Searching for Protoplanets around MWC 758 and MWC 480 in Br-γ Using Kernel Phase and SCExAO/CHARIS
The Astronomical JournalDiscovering new actively accreting protoplanets is crucial to answering open questions about planet formation. However, identifying such planets at orbital distances where they are expected to be abundant is extremely challenging, both due to the ...
Alexander Chaushev +8 more
doaj +1 more source