Results 61 to 70 of about 1,474,036 (268)

Functional comparison of EncB and EncC cargo proteins in iron storage within the Myxococcus xanthus encapsulin

open access: yesFEBS Letters, EarlyView.
Encapsulins are protein nanocompartments that play an important role in iron storage. In the Myxococcus xanthus encapsulin system, two cargo proteins called EncB and EncC contribute to iron mineralization. Here, we show that EncB and EncC generate iron‐containing minerals with distinct chemical compositions, suggesting that the composition of stored ...
Harry B. McDowell   +2 more
wiley   +1 more source

An Adaptive and Non-Linear Technique for Enhancement of High Contrast Images

open access: yes, 2007
In night time surveillance, there is a possibility of having extremely bright and dark regions in some image frames of a video sequence. Neither the object details in the low intensity areas nor in the high intensity areas can be clearly interpreted. Several image processing techniques have been developed to retrieve meaningful information under low ...
openaire   +2 more sources

The JWST Early Release Science Program for Direct Observations of Exoplanetary Systems. IV. NIRISS Aperture Masking Interferometry Performance and Lessons Learned

open access: yesThe Astrophysical Journal Letters
We present a performance analysis for the aperture masking interferometry (AMI) mode on board the James Webb Space Telescope Near Infrared Imager and Slitless Spectrograph (JWST/NIRISS).
Steph Sallum   +122 more
doaj   +1 more source

Structural and biochemical analysis of a B12 superbinder

open access: yesFEBS Letters, EarlyView.
BtuG proteins are vitamin B12 scavengers in Bacteroides thetaiotaomicron, a dominant human gut bacterium. We present crystal structures of three BtuG homologs bound to cobalamin and its precursor cobinamide, revealing picomolar binding affinities, among the highest known for any natural protein.
Jose M. Martinez Felices   +3 more
wiley   +1 more source

The JWST Early Release Science Program for Direct Observations of Exoplanetary Systems. III. Aperture Masking Interferometric Observations of the Star HIP 65426 at 3.8 μm

open access: yesThe Astrophysical Journal Letters
We present aperture masking interferometry (AMI) observations of the star HIP 65426 at 3.8 μ m, as part of the JWST Direct Imaging Early Release Science program, obtained using the Near Infrared Imager and Slitless Spectrograph instrument.
Shrishmoy Ray   +125 more
doaj   +1 more source

Structures of mycobacterial 3‐methylcrotonyl‐CoA carboxylase reveal carrier‐domain translocation between catalytic sites

open access: yesFEBS Letters, EarlyView.
Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav   +2 more
wiley   +1 more source

VLT/ERIS Observations of the V960 Mon System: A Dust-embedded Substellar Object Formed by Gravitational Instability?

open access: yesThe Astrophysical Journal Letters
V960 Mon is an FU Orionis object that shows strong evidence of a gravitationally unstable spiral arm that is fragmenting into several dust clumps. We report the discovery of a new substellar companion candidate around this young star, identified in high ...
Anuroop Dasgupta   +10 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

The Disks In Scorpius–Centaurus Survey (DISCS). I. Four Newly Resolved Debris Disks in Polarized Intensity Light

open access: yesThe Astronomical Journal
The presence of infrared excesses around stars directly correlates with spatially resolved imaging detections of circumstellar disks at both millimeter and optical/near-infrared wavelengths.
Justin Hom   +10 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

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