Results 61 to 70 of about 3,896,846 (293)

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Direct Images of CO2 Absorption in the Atmosphere of a Super-Jupiter: Enhanced Metallicity Suggestive of Formation in a Disk

The Astrophysical Journal Letters
It is unclear how directly imaged substellar companions with masses near the deuterium burning limit form, because these objects are rare and their bulk properties are not diagnostic of their formation.
William O. Balmer, Laurent Pueyo, Ashley Messier, Evelyn Bruinsma, Jeremy Jones, Klara Matuszewska, Marshall D. Perrin, Julien H. Girard, Jarron M. Leisenring, Kellen Lawson, Roeland P. van der Marel, Jens Kammerer, Aarynn Carter, Mathilde Mâlin, Kimberly Ward-Duong, Kielan K. W. Hoch, Emily Rickman, Sara Seager   +17 more
doaj   +1 more source

Nonlinear temporal pulse cleaning techniques and application

High Power Laser Science and Engineering, 2013
Two different pulse cleaning techniques for ultra-high contrast laser systems are comparably analysed in this work. The first pulse cleaning technique is based on noncollinear femtosecond optical-parametric amplification (NOPA) and second-harmonic ...
Yi Xu, Jianzhou Wang, Yansui Huang, Yanyan Li, Xiaomin Lu, Yuxin Leng   +5 more
doaj   +1 more source

TECHNIQUES FOR HIGH-CONTRAST IMAGING IN MULTI-STAR SYSTEMS. I. SUPER-NYQUIST WAVEFRONT CONTROL [PDF]

The Astrophysical Journal, 2015
Extra-solar planets direct imaging is now a reality with the deployment and commissioning of the first generation of specialized ground-based instruments (GPI, SPHERE, P1640 and SCExAO). These systems allow of planets $ 10 ^ 7 $ times fainter than their host star.
Thomas, Sandrine J., Belikov, Ruslan, Bendek, Eduardo   +2 more
openaire   +2 more sources

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

High-Contrast Fluorescence Microscopy for a Biomolecular Analysis Based on Polarization Techniques Using an Optical Interference Mirror Slide

Biosensors, 2014
Fluorescence microscopy with an improved contrast for fluorescence images is developed using an optical interference mirror (OIM) slide, which can enhance the fluorescence from a fluorophore as a result of the double interference of the excitation light ...
Mitsuru Yasuda, Takuo Akimoto
doaj   +1 more source

Simultaneous exoplanet detection and instrument aberration retrieval in multispectral coronagraphic imaging

, 2013
High-contrast imaging for the detection and characterization of exoplanets relies on the instrument's capability to block out the light of the host star.
Beuzit, Jean-Luc, Fusco, Thierry, Mouillet, David, Mugnier, Laurent M., Ygouf, Marie   +4 more
core   +3 more sources

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Comparing x-ray phase-contrast imaging using a Talbot array illuminator to propagation-based imaging for non-homogeneous biomedical samples

Scientific Reports, 2023
Phase-contrast computed tomography can visualize soft tissue samples with high contrast. At coherent sources, propagation-based imaging (PBI) techniques are among the most common, as they are easy to implement and produce high-resolution images.
Mirko Riedel, Kirsten Taphorn, Alex Gustschin, Madleen Busse, Joerg U. Hammel, Julian Moosmann, Felix Beckmann, Florian Fischer, Pierre Thibault, Julia Herzen   +9 more
doaj   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source