Results 41 to 50 of about 559,532 (297)

Potential significance of high-mobility group protein box 1 in cerebrospinal fluid

Heliyon, 2023
High-mobility group protein box 1 (HMGB1) is a cytokine with multiple functions (according to its subcellular location) that serves a marker of inflammation.
Zhiwu Wu, Liping Liang, Qianliang Huang
doaj   +1 more source

High Mobility Group Box 1 Protein Induction by Mycobacterium Bovis BCG

Mediators of Inflammation, 2007
High mobility group box 1 protein (HMGB1), a nuclear protein, is a critical cytokine that mediates the response to infection, injury, and inflammation.
Péter Hofner, György Seprényi, András Miczák, Krisztina Buzás, Zsófia Gyulai, Katalin F. Medzihradszky, Ari Rouhiainen, Heikki Rauvala, Yvette Mándi   +8 more
doaj   +1 more source

HMGB1-Induced Cross Talk between PTEN and miRs 221/222 in Thyroid Cancer [PDF]

, 2015
High mobility group box 1 (HMGB1) is an ubiquitous protein that plays different roles in the nucleus, cytoplasm and extra-cellular space. It is an important DAMP molecule that allows communication between damaged or tumor cells and the immune system ...
ANTONACI, Alfredo, FAGGIONI, Alberto, Fico, F., MARDENTE, Stefania, MARI, EMANUELA, MASSIMI, ISABELLA, PULCINELLI, FABIO MARIA, ZICARI, Alessandra   +7 more
core   +4 more sources

High mobility group box 1 (HMGB1) in COVID-19 [PDF]

Journal of Preventive Epidemiology, 2021
Fatemeh Kafi, Alireza Bolourian, Zahra Mojtahedi, Alireza Pouramini   +3 more
doaj   +1 more source

Evaluation of high mobility group box 1 protein as a presurgical diagnostic marker reflecting the severity of acute appendicitis. [PDF]

, 2012
RIGHTS : This article is licensed under the BioMed Central licence at http://www.biomedcentral.com/about/license which is similar to the 'Creative Commons Attribution Licence'.
Chi, Junmeng, Gong, Jianping, Guo, Hui, Liu, Qi, Sun, Hang, Wang, Hongliang, Wu, Chuanxin   +6 more
core   +2 more sources

High-mobility group box-1 and its role in angiogenesis [PDF]

Journal of Leukocyte Biology, 2014
AbstractHMGB1 is an architectural chromatin-binding protein that can be released actively by activated cells or passively by dying cells and can serve as a DAMP molecule to drive the pathogenesis of inflammatory and angiogenic diseases. Through TLR4 and RAGE signaling pathways, HMGB1 could regulate vascular growth in vivo and in vitro through diverse ...
Shuai, Yang, Linxinyu, Xu, Tianshu, Yang, Fang, Wang   +3 more
openaire   +2 more sources

A novel high mobility group box 1 neutralizing chimeric antibody attenuates drug-induced liver injury and postinjury inflammation in mice [PDF]

, 2016
Acetaminophen (APAP) overdoses are of major clinical concern. Growing evidence underlines a pathogenic contribution of sterile postinjury inflammation in APAP‐induced acute liver injury (APAP‐ALI) and justifies development of anti‐inflammatory therapies ...
Allhorn, Amara, Andersson, Antoine, Antoine, Antoine, Antoniades, Benkhoucha, Bhaskar, Bonaldi, Duncan, Ge, Gong, Huebener, Idusogie, Jaeschke, Kang, Knezevic, Kokkola, Lawson, Liu, McLean, Nandakumar, Nose, Ostapowicz, Qin, Scaffidi, Schiraldi, Sinclair, Stutchfield, Tiller, Tsung, Venereau, Wang, Watkins, Woolbright, Yang, Yang, Yang, Yang, Yang, Yang, Zhang   +42 more
core   +2 more sources

Serum high-mobility group box 1 protein level correlates with the lowest SaO2 in patients with sleep apnea: a preliminary study

Brazilian Journal of Otorhinolaryngology, 2022
Introduction: Serum level of high-mobility group box 1 protein is reportedly correlated with the severity of obstructive sleep apnea. Objective: We tried to evaluate the possibility of using the serum high-mobility group box 1 protein level as a biologic
Hyun Jin Min, Joon Soon Park, Kyung Soo Kim, Miran Kang, Ju Hee Seo, Joo-Heon Yoon, Chang-Hoon Kim, Hyung-Ju Cho   +7 more
doaj   +1 more source

High-Mobility Group Box-1 in Ischemia-Reperfusion Injury of the Heart [PDF]

Circulation, 2008
Background— High-mobility group box-1 (HMGB1) is a nuclear factor released by necrotic cells and by activated immune cells. HMGB1 signals via members of the toll-like receptor family and the receptor for advanced glycation end products (RAGE).
Andrassy, Martin, Volz, Hans C., Igwe, John C., Funke, Benjamin, Eichberger, Sebastian N., Kaya, Ziya, Buss, Sebastian, Autschbach, Frank, Pleger, Sven T., Lukic, Ivan K., Bea, Florian, Hardt, Stefan E., Humpert, Per M., BIANCHI, MARCO EMILIO, Mairbã¤url, Heimo, Nawroth, Peter P., Remppis, Andrew, Katus, Hugo A., Bierhaus, Angelika   +18 more
openaire   +2 more sources

Loss of ATF3 exacerbates liver damage through the activation of mTOR/p70S6K/ HIF-1α signaling pathway in liver inflammatory injury. [PDF]

, 2018
Activating transcription factor 3 (ATF3) is a stress-induced transcription factor that plays important roles in regulating immune and metabolic homeostasis.
Jiang, Bin, Jiang, Longfeng, Ke, Bibo, Li, Changyong, Lu, Ling, Ni, Xuhao, Wang, Han, Wang, Xuehao, Zhang, Feng, Zhu, Qiang   +9 more
core   +2 more sources