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The role of high mobility group proteins in cellular senescence mechanisms [PDF]

open access: yesFrontiers in Aging
Aging is a universal physiological phenomenon, and chronic age-related diseases have become one of the leading causes of human mortality, accounting for nearly half of all deaths.
Jia Chen   +3 more
doaj   +7 more sources

High Mobility Group Proteins in Sepsis [PDF]

open access: yesFrontiers in Immunology, 2022
Sepsis, a systemic inflammatory response disease, is the most severe complication of infection and a deadly disease. High mobility group proteins (HMGs) are non-histone nuclear proteins binding nucleosomes and regulate chromosome architecture and gene ...
Guibin Liang, Zhihui He
doaj   +4 more sources

High mobility group proteins and their post-translational modifications [PDF]

open access: yesBiochimica Et Biophysica Acta - Proteins and Proteomics, 2008
The high mobility group (HMG) proteins, including HMGA, HMGB and HMGN, are abundant and ubiquitous nuclear proteins that bind to DNA, nucleosome and other multi-protein complexes in a dynamic and reversible fashion to regulate DNA processing in the context of chromatin.
Yinsheng Wang
exaly   +5 more sources

A Mini Review of the High Mobility Group Proteins of Insects [PDF]

open access: yesBiochemical Genetics, 2003
High mobility group (HMG) proteins are an abundant class of chromosomal proteins facilitate assembly of higher order structures. The mammalian HMG proteins have been grouped into three distinct families on the basis of their characteristic functional sequence: the HMGB, the HMGN, and the HMGA family.
Aleporou-Marinou, V.   +2 more
exaly   +5 more sources

High Mobility Group A (HMGA) proteins as tumor markers [PDF]

open access: yesFrontiers in Medicine, 2015
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Pierlorenzo ePallante   +3 more
doaj   +5 more sources

The alarmin functions of high-mobility group proteins. [PDF]

open access: yesBiochim Biophys Acta, 2010
High-mobility group (HMG) proteins are non-histone nuclear proteins that bind nucleosomes and regulate chromosome architecture and gene transcription. Over the past decade, numerous studies have established that some HMG proteins can be released extracellularly and demonstrate distinct extracellular biological activities.
Yang D   +4 more
europepmc   +4 more sources

Regulation of HMGB1 Release in Health and Diseases

open access: yesCells, 2022
Almost a half century ago, a group of nuclear proteins were co-purified with histones from calf thymus and termed as “high mobility group” (HMG) proteins because of their relative rapid mobility on SDS-PAGE gels [...]
Haichao Wang
doaj   +1 more source

High mobility group proteins in ram spermatids [PDF]

open access: yesExperimental Cell Research, 1986
The four major high mobility group proteins HMG 1, 2, 14 and 17, HMG 19B and histone H1(0) were identified in the ram testis by their extraction and solubility characteristics and by their electrophoretic mobilities. HMG 14 and 17 were isolated by chromatography and amino acid analysis revealed that they were similar to their calf thymus analogues.
Loir, Maurice   +4 more
openaire   +5 more sources

Paraformaldehyde Fixation May Lead to Misinterpretation of the Subcellular Localization of Plant High Mobility Group Box Proteins. [PDF]

open access: yesPLoS ONE, 2015
Arabidopsis High Mobility Group Box (HMBG) proteins were previously found associated with the interphase chromatin but not the metaphase chromosome.
Man-Wah Li, Liang Zhou, Hon-Ming Lam
doaj   +1 more source

High Mobility Group A proteins in esophageal carcinomas [PDF]

open access: yesCell Cycle, 2016
We have recently shown that HMGA2 is overexpressed in esophageal squamous cell carcinoma (ESCC) and its detection allows to discriminate between cancer and normal surrounding tissue proposing HMGA2 as a novel diagnostic marker. Interestingly, esophageal adenocarcinoma shows an opposite behavior with the overexpression of HMGA1 but not HMGA2.
Palumbo Junior A   +4 more
openaire   +3 more sources

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