Results 81 to 90 of about 204,374 (297)
A Systematic Nomenclature for the Redox States of High Mobility Group Box (HMGB) Proteins [PDF]
, 2014 High mobility group box 1 (HMGB1) is a central mediator in inflammation and immunity. Recently, it was shown that different redox states of the three cysteines of HMGB1 endow it with mutually exclusive activities, such as inducing chemotaxis or the ...
Tracey, K. J. +4 more
core +2 more sources
HMGB2 Protein from the Marine Sponge Suberites domuncula
Food Technology and Biotechnology, 2003 Investigation of the phylogenetically conserved genes/proteins from marine sponges (Porifera), the most primitive metazoan phylum, can be applied for the reconstruction of ancient structures of genome/proteom complexity in the ancestral organism common ...
Lada Lukić-Bilela, Helena Ćetković
doaj
Expression and functional characterization of Xhmg-at-hook genes in Xenopus laevis. [PDF]
PLoS ONE, 2013 High Mobility Group A proteins (HMGA1 and HMGA2) are architectural nuclear factors involved in development, cell differentiation, and cancer formation and progression.
Simone Macrì +8 more
doaj +1 more source
Mass spectrometry based identification of AMP‐O‐Tris generated by Thermococcus onnurineus Cas10
FEBS Open Bio, EarlyView.Isolated Thermococcus onnurineus Cas10 generates the noncanonical ATP‐derived product AMP‐O‐Tris while in Tris‐containing buffer as identified via mass spectrometry, revealing relaxed nucleophile selectivity under isolated conditions. These findings suggest that multiprotein Csm complex assembly restricts Cas10 reactivity toward canonical cyclic ...
Su‐Jin Lee +6 more
wiley +1 more source
The Role of Alarmins in the Pathogenesis of Atherosclerosis and Myocardial Infarction
Current Issues in Molecular BiologyAtherosclerosis is a condition that is associated with lipid accumulation in the arterial intima. Consequently, the enlarging lesion, which is also known as an atherosclerotic plaque, may close the blood vessel lumen, thus leading to organ ischaemia ...
Kajetan Kiełbowski +4 more
doaj +1 more source
FEBS Open Bio, EarlyView.The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer +7 more
wiley +1 more source
Nutrition & Metabolism, 2018 Advanced glycation end products (AGEs), a group of compounds that are formed by non-enzymatic reactions between carbonyl groups of reducing sugars and free amino groups of proteins, lipids or nucleic acids, can be obtained exogenously from diet or formed
Jie-Hua Chen +3 more
doaj +1 more source
FEBS Open Bio, EarlyView.Evolutionary analysis across 32 placental mammals identified positive selection at residues H148 and W149 in the immune receptor FcγR1. Ancestral reconstruction combined with molecular dynamics simulations reveals how these mutations may influence receptor structure and dynamics, providing insight into the evolution of antibody recognition and immune ...
David A. Young +7 more
wiley +1 more source
A high mobility group protein from the dipteran insects Ceratitis capitata and Bactrocera oleae [PDF]
, 2003 Nuclei from Bactrocera oleae and Ceratitis capitata larvae contain a major protein that shares most of the characteristics of vertebrate high mobility group (HMG) proteins. Proteins are extracted from nuclei with 0.35 M NaCl, are soluble in 5% perchloric
Patargias, T. +5 more
core
Alarmins and Clinical Outcomes After Major Abdominal Surgery—A Prospective Study
Journal of Investigative Surgery, 2017 Purpose: Tissue injury causing immune response is an integral part of surgical procedure. Evaluation of the degree of surgical trauma could help to improve postoperative management and determine the clinical outcomes.
Jan Máca +5 more
doaj +1 more source