Results 111 to 120 of about 280,529 (308)

Increased throughput and ultra-high mass resolution in DESI FT-ICR MS imaging through new-generation external data acquisition system and advanced data processing approaches [PDF]

, 2019
Desorption electrospray ionisation-mass spectrometry imaging (DESI-MSI) is a powerful imaging technique for the analysis of complex surfaces. However, the often highly complex nature of biological samples is particularly challenging for MSI approaches ...
Tsybin, YO, Heeren, Ron M. A., Kooijman, Pieter C., Ellis, SR, Kozhinov, Anton N., Nagornov, KO, Heeren, RMA, Kilgour, David P. A., Kilgour, DPA, Ellis, Shane R., Kozhinov, AN, Nagornov, Konstantin O., Kooijman, PC, Tsybin, Yury O.   +13 more
core   +1 more source

Hyperactive ice‐binding proteins stabilize cell membranes and improve resistance to dehydration stress in Caenorhabditis elegans

FEBS Open Bio, EarlyView.
TisIBP8, a fungal‐derived hyperactive ice‐binding protein, helps Caenorhabditis elegans survive dehydration. It localizes near cell membranes, reduces cell damage, and helps maintain membrane structure during drying. These results suggest that ice‐binding proteins can protect cells from dehydration stress as well as freezing stress.
Daiki Shimose, Kotaro Ozaki, Ryohei Kuriyama, Yuka Ikemoto, Kazuhiro Mio, Yuji C. Sasaki, Tatsuya Arai, Sakae Tsuda, Yoichi Shinkai, Masahiro Kuramochi   +9 more
wiley   +1 more source

Rapid typing and subtyping of vaccine strains of the influenza virus with high resolution mass spectrometry

, 2010
The application of high-resolution mass spectrometry to type and subtype strains of the influenza virus within recent recommended vaccine formulations is described.
Jason W.H. Wong, Schwahn, Alexander B., Wong, Jason W H, Downarda, Kevin M., Kevin M. Downard, Alexander B. Schwahn   +5 more
core   +1 more source

Loss of AMBRA1 activates MAPK and angiogenesis signaling pathways in melanoma cells

FEBS Open Bio, EarlyView.
Loss of AMBRA1 in melanoma cells activates multiple oncogenic pathways associated with tumor progression. Transcriptomic and protein network analyses revealed that AMBRA1 depletion enhances MAPK/ERK signaling, angiogenesis, TGF‐β/EMT signaling, and Wnt/axon guidance pathways.
Milad Ibrahim, Marco Corazzari, Iman Osman, Jane Armstrong, Noel Carter   +4 more
wiley   +1 more source

Automated high resolution mass spectrometry for the synthetic chemist

Journal of the American Society for Mass Spectrometry, 1999
Exact mass measurement at high resolution is an important tool alongside other spectroscopic methods to help confirm the structure of a novel compound prepared by the synthetic chemist. Exact mass measurement is used in the pharmaceutical industry to confirm the expected empirical formula of a product when problems have been experienced using elemental
Perkins, George, Pullen, Frank, Thompson, Christine   +2 more
openaire   +2 more sources

Parsimonious Charge Deconvolution for Native Mass Spectrometry

, 2018
Charge deconvolution infers the mass from mass over charge (m/z) measurements in electrospray ionization mass spectra. When applied over a wide input m/z or broad target mass range, charge-deconvolution algorithms can produce artifacts, such as false ...
Christopher Becker (1298982), Carlson, Eric, Doron Kletter, Yong J. Kil, Tomislav Caval, Franc, Vojtech, K. Ilker Sen (2311798), Dominique Hagemans, K. Ilker Sen, Becker, Christopher, Nicolas Galy, Marshall Bern (802724), Dominique Hagemans (4840668), Kil, Yong J, Eric Carlson, Eric Carlson (3928799), Nicolas Galy (4840665), Vojtech Franc, Caval, Tomislav, Christopher Becker, Hagemans, Dominique, Sen, K Ilker, Heck, Albert J R, Albert J. R. Heck (9680), Kletter, Doron, Doron Kletter (802722), Vojtech Franc (3817549), Galy, Nicolas, Yong J. Kil (2058790), Marshall Bern, Sub Biomol.Mass Spectrometry & Proteom., Biomolecular Mass Spectrometry and Proteomics, Wilfred Tang (4840671), Bern, Marshall, Tomislav Caval (3622946), Wilfred Tang, Albert J. R. Heck, Tang, Wilfred, Afd Biomol.Mass Spect. and Proteomics   +38 more
core   +1 more source

N-Terminal-oriented proteogenomics of the marine bacterium Roseobacter Denitrificans Och114 using N-Succinimidyloxycarbonylmethyl)tris(2,4,6-trimethoxyphenyl)phosphonium bromide (TMPP) labeling and diagonal chromatography. [PDF]

, 2014
Given the ease of whole genome sequencing with next-generation sequencers, structural and functional gene annotation is now purely based on automated prediction.
Armengaud, J., Bland, C., Hartmann, E. M., Armengaud, Jean, Bland, Céline, Christie-Oleza, Joseph Alexander, Fernandez, Bernard, Hartmann, Erica M.   +7 more
core   +1 more source

MagmaFlow: A desktop platform for artificial intelligence‐driven expression analysis

FEBS Open Bio, EarlyView.
MagmaFlow is a free, no‐code platform for gene expression analysis. It generates interactive volcano plots, links genes to literature, pathways, and diseases, prioritizes candidates using millions of publications, identifies affected biological processes, builds network diagrams, and exports publication‐ready figures and reports for macOS and Windows ...
Carlos E. Buss, Ao Li, Eduardo H. Gilglioni, Mayank Bansal, Sumeet Pal Singh, Latifa Bakiri, Alessandra K. Cardozo, Esteban N. Gurzov   +7 more
wiley   +1 more source

Analysis of Ginsenoside Isomers by Inlet Ionization-High Resolution Mass Spectrometry

Zhipu Xuebao
The ginsenoside isomers were analyzed and distinguished by using inlet ionization-high resolution mass spectrometry technology under positive and negative ion modes with optimum inlet temperatures.
Yun-long GUO, Hong-yue CHI, Yang WANG, Fei ZHENG, Yu-lin DAI, Xin HUANG, Hao YUE, Shu-ying LIU   +7 more
doaj   +1 more source

Plasma EV Proteomics Identifies ECM Remodeling and Inflammatory Proteins LUM and C7 as Candidate Biomarkers in FSHD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Facioscapulohumeral muscular dystrophy (FSHD) is one of the most debilitating and common muscular dystrophies. Despite its severity, no approved therapy exists for FSHD patients. However, several therapeutic candidates are currently under development, and some have recently entered clinical trials, marking the need for reliable ...
Mustafa Bilal Bayazit, Chiranth K. Nagaraj, Jackson S. Newell, Kim Truc Nguyen, Xilal Y. Rima, Jacob Doon‐Ralls, Eduardo Reátegui, Jeffrey M. Statland, Rabi Tawil, Kevin M. Flanigan, Scott Q. Harper, Nizar Y. Saad   +11 more
wiley   +1 more source