Results 21 to 30 of about 321,953 (262)
High throughput genetic sequence analysis [PDF]
Proceedings of the 11th ACM Conference on Computing Frontiers, 2014 We present an application paradigm in which an unsupervised machine learning approach is applied to high dimensional influenza sequence datasets: (1) human A/H3N2, (2) avian H5, and (3) North American swine influenza H3N2 virus. Interesting visual patterns observed in the A/H3N2 influenza virus led us to hypothesize that vaccination could be one of the
Ham Ching Lam +3 more
openaire +1 more source
High Throughput Sequencing for Detection of Foodborne Pathogens
Frontiers in Microbiology, 2017 High-throughput sequencing (HTS) is becoming the state-of-the-art technology for typing of microbial isolates, especially in clinical samples. Yet, its application is still in its infancy for monitoring and outbreak investigations of foods.
Camilla Sekse +6 more
doaj +1 more source
Frontiers in Microbiology, 2021 Mucoromycotina are often considered mainly in pathogenic context but their biology remains understudied. We describe the genomes of six Mucoromycotina fungi representing distant saprotrophic lineages within the subphylum (i.e., Umbelopsidales and ...
Anna Muszewska +14 more
doaj +1 more source
First occurrence of bidens mottle virus in Brazil: biological and molecular characterization of isolates infecting Zinnia sp. and Bidens pilosa [PDF]
Scientia Agricola, 2023 Zinnia sp. and hairy beggartick (Bidens pilosa) plants exhibiting symptoms of possible virus infection were found in the municipality of Santa Bárbara d’Oeste, São Paulo State, Brazil.
Gabriel Madoglio Favara +8 more
doaj +1 more source
Ion torrent high throughput mitochondrial genome sequencing (HTMGS).
PLoS ONE, 2019 The implementation and popularity of next generation sequencing (NGS) has led to the development of various rapid whole mitochondrial genome sequencing techniques. We summarise an efficient and cost-effective NGS approach for mitochondrial genomic DNA in
N R Harvey +10 more
doaj +1 more source
Targeted high throughput sequencing in hereditary ataxia and spastic paraplegia. [PDF]
PLoS ONE, 2017 Hereditary ataxia and spastic paraplegia are heterogeneous monogenic neurodegenerative disorders. To date, a large number of individuals with such disorders remain undiagnosed.
Zafar Iqbal +8 more
doaj +1 more source
Optimal assembly for high throughput shotgun sequencing [PDF]
BMC Bioinformatics, 2013 We present a framework for the design of optimal assembly algorithms for shotgun sequencing under the criterion of complete reconstruction. We derive a lower bound on the read length and the coverage depth required for reconstruction in terms of the repeat statistics of the genome.
Bresler, Guy +2 more
openaire +5 more sources
High-Throughput Sequencing and Rare Genetic Diseases [PDF]
Molecular Syndromology, 2012 High-throughput sequencing has drastically changed the research of genes responsible for genetic disorders and is now gradually introduced as an additional genetic diagnostic testing in clinical practice. The current debates on the emerging technical, medical and ethical issues as well as the potential optimum use of the available technology are ...
Makrythanasis P, Antonarakis SE.
openaire +3 more sources
Nature Communications, 2023 MicroRNAs (miRNAs) regulate fundamental biological processes by silencing mRNA targets and are dysregulated in many diseases. Therefore, miRNA replacement or inhibition can be harnessed as potential therapeutics.
Lien D. Nguyen +11 more
doaj +1 more source
High-throughput single-сell sequencing in cancer research
Signal Transduction and Targeted Therapy, 2022 With advances in sequencing and instrument technology, bioinformatics analysis is being applied to batches of massive cells at single-cell resolution. High-throughput single-cell sequencing can be utilized for multi-omics characterization of tumor cells,
Qingzhu Jia +4 more
doaj +1 more source