Results 101 to 110 of about 4,290,191 (312)

The heterodimeric amino acid transporters (HAT) of the SLC7/SLC3 family: A structure−function relationships and relevance to human pathology

FEBS Letters, EarlyView.
Heterodimeric amino acid transporters consist of SLC7 and SLC3 family proteins arranged in a conserved structural organization. They regulate nutrient transport across cell membranes, supporting essential cellular functions. These transporters also contribute to xenobiotic/drug uptake and distribution.
Mariafrancesca Scalise, Tiziano Mazza, Raffaella Scanga, Lara Console, Michele Galluccio, Cesare Indiveri   +5 more
wiley   +1 more source

Knowledge discovery from mining the association between H5N1 outbreaks and environmental factors [PDF]

, 2010
The global spread of highly pathogenic avian influenza H5N1 in poultry, wild birds and humans, poses a significant panzootic threat and a serious public health risk.
Si, Y., Wang, Tiejun; id_orcid, Prins, H. H T, Wang, T., Si, Y. L., Skidmore, A.K., Skidmore, A. K., Prins, H.H.T.   +7 more
core  

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

Invisible but not inaccessible—Revealing transient oligomers formed by intrinsically disordered proteins with solution NMR and complementary methods

FEBS Letters, EarlyView.
Transient oligomers formed by intrinsically disordered proteins may be ‘invisible’ to direct detection yet remain accessible to solution NMR through equilibrium‐exchange measurements and pressure‐jump experiments. Complementary methods report on mass, stoichiometry, selected distance distributions, morphology, and internal packing.
Martin D. Gelenter, Ad Bax
wiley   +1 more source

Questions and answers: highly pathogenic avian influenza

, 2004
2 pages.FAQ about Highly Pathogenic Avian Influenza (HPAI)
United States. Department of Agriculture. Animal and Plant Health Inspection Service.
core   +1 more source

Neutralization of the PTX3/CD44 axis suppresses TGF‐β1 signaling in kidney fibrosis

FEBS Letters, EarlyView.
This study investigates how the PTX3/CD44 axis promotes kidney fibrosis by activating TGF‐β1 signaling. We demonstrate that the neutralizing antibody WHC‐001 effectively inhibits this pathway, suppressing myofibroblast activation and partial epithelial–mesenchymal transition (EMT).
Chao‐Chun Cheng, Shen‐Shin Chang, Feng‐Wei Chen, Ying‐Chieh Su, Thanh Phuong Nguyen, Yu‐Wei Hsiao, Jhih‐Ying Chi, Hsin‐Yin Liang, Ju‐Ming Wang   +8 more
wiley   +1 more source

Highly pathogenic H5N1 influenza virus in smuggled Thai eagles, Belgium.

, 2005
<p>We report the isolation and characterization of a highly pathogenic avian influenza A/H5N1 virus from Crested Hawk-Eagles smuggled into Europe by air travel.
M. Boschmans, Mireille Decaestecker, R. Snacken, G. Dupont, Isabelle Thomas, Thierry van den Berg, T. van den Berg, Steven Van Borm, Germaine Hanquet, Marc Boschmans, Bénédicte Lambrecht, Gérald Dupont, B. Lambrecht, S. Van Borm, G. Hanquet, I. Thomas, René Snacken, M. Decaestecker   +17 more
core   +1 more source

Identification and expression analysis of antibacterial peptides from venom of the scorpion Mesobuthus martensii

Frontiers in Microbiology
IntroductionAs one kind of important component of animal innate immune system, many antibacterial peptides (ABPs) have been characterized from scorpion venoms.
Gaomin Liu, Jiaqi Xu, Yan Tan, Wenzhen Wang, Hua Ling, Zhijian Cao, Zhifeng Li   +6 more
doaj   +1 more source

Hemoparasites in a wild primate: Infection patterns suggest interaction of Plasmodium and Babesia in a lemur species

International Journal for Parasitology: Parasites and Wildlife, 2015
Hemoparasites can cause serious morbidity in humans and animals and often involve wildlife reservoirs. Understanding patterns of hemoparasite infections in natural populations can therefore inform about emerging disease risks, especially in the light of ...
Andrea Springer, Claudia Fichtel, Sébastien Calvignac-Spencer, Fabian H. Leendertz, Peter M. Kappeler   +4 more
doaj   +1 more source