Results 81 to 90 of about 4,290,191 (312)
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
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The surveillance and risk assessment of wild birds in northern Australia for highly pathogenic avian influenza H5N1 virus [PDF]
, 2012 Highly pathogenic avian influenza (HPAI), caused by infection with H5N1 virus, is a transboundary disease which has had a significant socio-economic impact on the poultry production systems of Eurasia, and spillover events with mortality in humans and ...
Curran, John
core
Frontiers in MicrobiologyThe foodborne pathogen Burkholderia gladioli pv. cocovenenans (B. cocovenenans) produces the lethal mitochondrial toxin bongkrekic acid (BA). To more accurately assess the toxin production levels of toxigenic strains, it is necessary to further optimize ...
Peidong Tian +10 more
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A Next-Generation Sequencing Approach Uncovers Viral Transcripts Incorporated in Poxvirus Virions
Viruses, 2017 Transcripts are known to be incorporated in particles of DNA viruses belonging to the families of Herpesviridae and Mimiviridae, but the presence of transcripts in other DNA viruses, such as poxviruses, has not been analyzed yet.
Marica Grossegesse +4 more
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BMC Infectious Diseases, 2022 Background SARS-CoV-2 cases in Germany increased in early March 2020. By April 2020, cases among health care workers (HCW) were detected across departments at a tertiary care hospital in Berlin, prompting a longitudinal investigation to assess HCW SARS ...
Sara Tomczyk +11 more
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The microbiome in human skin aging
FEBS Letters, EarlyView.Age‐related skin changes encompass the well‐known visible phenotypic alterations, together with microbiome dysbiosis and a series of molecular aging hallmarks. These hallmarks characterize not only a fully stablished aged phenotype but also the skin aging process itself.
Manuel Huerta Arana +3 more
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FEBS Letters, EarlyView.This review focuses on the role of autophagy and mitophagy in maintaining pancreatic β‐cell function and homeostasis. We discuss how genetic defects affecting these pathways contribute to the development of type 1, type 2, monogenic, and gestational diabetes. We further explore their potential as therapeutic targets. Created in BioRender.
Yunkyeong Lee +2 more
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BMC MicrobiologyBackground The zoonotic pathogen Francisella tularensis is the etiological agent of tularemia. Tularemia in humans is mainly caused by F. tularensis subspecies tularensis and holarctica, but beneath some opportunistic Francisella species, like F ...
Kristin Köppen +2 more
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Frontiers in Microbiology, 2018 High-risk ESBL-producing Enterobacteriaceae (ESBL-E) have been described in wild birds and rodents worldwide. Rats are of special interest not only due to their indicator role for environmental pollution with multi-resistant bacteria but also as possible
Katharina Schaufler +10 more
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Emerging experimental and computational methods for studying redox‐regulated structural transitions
FEBS Letters, EarlyView.Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass +2 more
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