Results 91 to 100 of about 4,290,191 (312)

CANDIDA AURIS: EMERGENCE AND EPIDEMIOLOGY OF A HIGHLY PATHOGENIC YEAST

open access: yesClinical & Biomedical Research, 2017
Candida auris is a multidrug-resistant emerging yeast, which was responsible for healthcare-associated infection outbreaks, and was cataloged as a new species in 2009, after being isolated from a patient’s ear canal secretion in Japan. Since the notification of this first occurrence, numerous cases have been reported throughout the world, including ...
Santos, Paula Slomp   +2 more
openaire   +5 more sources

Tularemia in Germany—A Re-emerging Zoonosis

open access: yesFrontiers in Cellular and Infection Microbiology, 2018
Tularemia, also known as “rabbit fever,” is a zoonosis caused by the facultative intracellular, gram-negative bacterium Francisella tularensis. Infection occurs through contact with infected animals (often hares), arthropod vectors (such as ticks or deer
Mirko Faber   +4 more
doaj   +1 more source

The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation

open access: yesFEBS Letters, EarlyView.
Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge   +6 more
wiley   +1 more source

Epidemiology study and risk assessments of highly pathogenic avian influenza H5N1 in free flying birds in Thailand [PDF]

open access: yes, 2010
The highly pathogenic avian influenza virus H5N1 was the cause of a pandemic of avian influenza in poultry throughout many parts of the world. The role of wild birds in the transmission and cycling of this virus has been uncertain and the current study ...
Siengsanan-Lamont, Jarunee
core  

Characterization of highly pathogenic avian influenza A (H5N1) viruses isolated from cats in South Korea, 2023

open access: yes, 2023
Characterization of highly pathogenic avian influenza A (H5N1) viruses isolated from cats in South Korea ...
Minjoo Yeom (3465203)   +8 more
core   +1 more source

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

L‐aspartate oxidase provides new insights into fumarate reduction in anaerobic darkness in Synechocystis sp. PCC6803

open access: yesFEBS Letters, EarlyView.
Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil   +3 more
wiley   +1 more source

Urine metabolomic analyses reveal metabolite disruptions in steroid hormone biosynthesis in monkeypox

open access: yesiScience
Summary: Monkeypox virus (MPXV) poses a global health threat. Viral infection can alter host metabolic homeostasis, while its changes may influence disease severity and progression. The relationship between MPXV and metabolites has not been reported.
Xiaofeng Yang   +19 more
doaj   +1 more source

RNA‐related functions of BRCA2 in transcription, replication, and genome stability

open access: yesFEBS Letters, EarlyView.
Beyond its role in homologous recombination, BRCA2 regulates R‐loop homeostasis, DNA–RNA hybrid resolution, RNA polymerase II dynamics, and transcriptional activation. Disruption of any of these functions can contribute to genome instability, inflammatory signaling, and tumorigenesis. BRCA2 is a central tumor suppressor protein best known for its roles
Lucia Alvaro‐Aranda   +2 more
wiley   +1 more source

First European detection and genomic analysis of Francisella tularensis subsp. tularensis in a traveler returning from Canada

open access: yesIDCases
Tularemia is a zoonotic disease caused by the gram negative coccobacillus Francisella tularensis, a Biosafety Level 3 pathogen and potential bioterrorism agent. We report here the first European human case of tularemia caused by F.
Ophélie Rutschmann   +8 more
doaj   +1 more source

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