Results 71 to 80 of about 5,403 (145)

Ponovljivost i reproducibilnost HILIC-UPLC i xCGE-LIF metoda u pripremi i analizi N-glikana proteina plazme i imunoglobulina G

, 2020
Glikani na proteinima imaju značajnu ulogu u međudjelovanju makromolekula, sudjeluju u procesu smatanja i sekrecije proteina te utječu na njihovu stabilnost, vrijeme poluživota i funkciju. Najvažnije svojstvo glikokonjugata je njihova mikroheterogenost, odnosno postojanje različitih glikanskih struktura vezanih na isti protein.
openaire   +2 more sources

Strukturna analiza N-glikanskog profila ukupnih proteina plazme miša soja DBA/2 HILIC-UPLC-FLR-MS/MS metodom

, 2018
Glikozilacija proteina je složena kotranslacijska i postranslacijska modifikacija posredovana enzimima u kojoj dolazi do kovalentnog vezanja šećernih struktura na proteine. Glikanski dio utječe na svojstva i funkciju glikoproteina. Istraživanjima se sve više utvrđuje povezanost glikana s različitim patofiziološkim stanjima te zbog toga oni postaju ...
openaire   +1 more source

Untargeted and Targeted Cerebrospinal Fluid Neurometabolomics via Chromatography-Mass Spectrometry-Based Methods. [PDF]

Molecules
Pautova AK.
europepmc   +1 more source

A simple and highly sensitive LC-MS/MS bioanalytical method for phosphorodiamidate morpholino oligonucleotides in plasma. [PDF]

Bioanalysis
Kameyama T, Imai S, Mitamura R, Niwa M, Yamada T, Kusano K.   +5 more
europepmc   +1 more source

Evaluation of HILIC-UPLC-MS Metabolic Profiling of Urine: Application to Toxicological Studies

Frontiers in Pharmacology, 2010
openaire   +1 more source

Recent progress in the application of hydrophilic interaction liquid chromatography for the separation and analysis of traditional Chinese medicine. [PDF]

Front Chem
Wu Y, Huang H, Zhao X, Lin J, Guo J, Jiang Z, Ar-Sanork K, Deng T, Xu D.   +8 more
europepmc   +1 more source

Impact of Selected Pre-Analytical and Analytical Factors on Untargeted Salivary Metabolomics. [PDF]

Int J Mol Sci
Michorowska S, Zięba A, Olczak-Kowalczyk D, Giebułtowicz J.   +3 more
europepmc   +1 more source

Decoding Cerebrospinal Fluid: Integrative Metabolomics Across Multiple Platforms. [PDF]

Methods Protoc
Presset A, Bodard S, Lefèvre A, Oujagir E, Dupuy C, Escoffre JM, Nadal-Desbarats L.   +6 more
europepmc   +1 more source

Benchmarking untargeted metabolomics data quality with allopurinol-induced perturbations. [PDF]

Metabolomics
Vasskog T, Heinsvig PJ, Sharashova E, Hansen T, Myhre TN, Mardal M.   +5 more
europepmc   +1 more source

Comparative Analysis of Glycan Composition in Therapeutic Antibodies via Glycan Profiling and Intact Mass Analysis. [PDF]

Molecules
Chun YS, Lee JB, Seomun S, Park S, Na JH, Ko BJ.   +5 more
europepmc   +1 more source