Results 51 to 60 of about 5,381 (125)
PLoS ONE, 2019 A fixed dose combination of lesinurad and allopurinol has been recently approved by USFDA and EMA for treatment of gout-associated hyperuricemia in patients who have not achieved target serum uric acid levels with allopurinol alone.
Muzaffar Iqbal +3 more
doaj +1 more source
Protein hydrolysates in cell culture: Toward multi‐omics characterization
Biotechnology Progress, Volume 42, Issue 4, July/August 2026.While protein hydrolysates are widely used in cell culture applications, they remain undefined and variable products. Multi‐omic characterization evaluating composition and function can transition hydrolysates toward semi‐defined media components.
Michelle Combe +3 more
wiley +1 more source
ELECTROPHORESIS, Volume 47, Issue 7, Page 620-628, July 2026.The separation of selected mycosporine‐like amino acids and two biosynthetic precursors, in total 13 compounds, by HILIC‐UPLC is described for the first time. With an analysis time of only 5 min, it surpasses all currently known methods for analysis of these promising natural products.
Armin Oberosler +6 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 7, July 2026.Steviol Glycosides (E960) from Stevia rebaudiana: Technological Innovations, Safety Assessment, Regulatory Aspects and their Role in Sustainable Food Systems. ABSTRACT Stevia (Stevia rebaudiana Bertoni) is a small perennial herb widely recognized as a natural sweetener.
Aswin Sakthivel Manoharan +1 more
wiley +1 more source
Food Science &Nutrition, Volume 14, Issue 7, July 2026.In a 4‐week self‐controlled trial of 73 young seafarers, consumption of chitooligosaccharides‐combination fortified noodles every other day significantly reduced visceral fat area, waist circumference, serum leptin, and LDL‐C, and elevated skeletal muscle index, without altering body weight.
Zhongbo Bian +7 more
wiley +1 more source
Provenance legacies override species effects in shaping oak rhizosphere microbiomes and metabolomes
New Phytologist, Volume 251, Issue 1, Page 488-504, July 2026.Graphical representation of experimental setup. Quercus spp. seeds were collected at two origins: upper Rhine basin (URB) and north German lowland (NGL). Summary As climate change drives more frequent drought‐heat extremes, selecting drought‐tolerant trees is crucial for future forest resilience. However, the role of tree–microbial associations remains
Sebastian Bibinger +9 more
wiley +1 more source
New Phytologist, Volume 251, Issue 1, Page 438-454, July 2026.Summary Beneficial, facultative endophytes help plants thrive in challenging environments by altering their host's metabolism, but how these cellular scale metabolic changes propagate to the systems biology scale is unknown. In this work, we employed a high‐resolution chemical imaging approach to map metabolic changes at the Populus trichocarpa root ...
Jayde Aufrecht +9 more
wiley +1 more source
Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase
ChemBioChem, Volume 27, Issue 12, 26 June 2026.Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal +7 more
wiley +1 more source
Dilute and Shoot: A novel approach for determination of chlormequat and mepiquat in beer
Kvasný průmyslThe extensive use of pesticides in agriculture has led to the presence of their residues in soil, water sources, and crops. Among these, the plant growth regulators chlormequat and mepiquat are commonly employed to regulate plant growth.
Marek Pernica +6 more
doaj +1 more source
Acta Pediátrica de México, 2016 ANTECEDENTES: fraccionar o pulverizar tabletas de metformina para ajustar dosis pediátricas dificulta su administración, genera inestabilidad del fármaco (oxidación/fotosensibilidad) y relativiza su biodisponibilidad.
L Rivera-Espinosa +5 more
doaj +1 more source