Results 51 to 60 of about 5,403 (145)

Determination of Phospholipids in Antarctic Krill by Hydrophilic Interaction Ultra-high Performance Liquid Chromatography-Tandem Mass Spectrometry Using TiO2/KCC-1 Solid Phase Extraction [PDF]

open access: yesShipin Kexue
Phosphatidylcholine (PC), phosphatidyl ethanolamine (PE), phosphatidylserine (PS), and phosphatidylinositol (PI) are the four major phospholipids in Antarctic krill.
ZHANG Xintong, TANG Guangzhi, SHEN Qing, LEI Min, TAN Shuping, LIN Biling, ZHOU Ruiqi, LIANG Xiubi, GUO Lianxian, LI Linqiu
doaj   +1 more source

Provenance legacies override species effects in shaping oak rhizosphere microbiomes and metabolomes

open access: yesNew Phytologist, Volume 251, Issue 1, Page 488-504, July 2026.
Graphical representation of experimental setup. Quercus spp. seeds were collected at two origins: upper Rhine basin (URB) and north German lowland (NGL). Summary As climate change drives more frequent drought‐heat extremes, selecting drought‐tolerant trees is crucial for future forest resilience. However, the role of tree–microbial associations remains
Sebastian Bibinger   +9 more
wiley   +1 more source

Determination of γ-aminobutyric acid in beverages by UPLC-MS/MS and its dietary exposure risk assessment [PDF]

open access: yesZhongguo niangzao
A rapid analytical method for the determination of γ-aminobutyric acid in beverages was established based on ultra-high performance liquid chromatogram-tandem mass spectrometry (UPLC-MS/MS), and the dietary risk of γ-aminobutyric acid in beverages was ...
MIN Yuhang, XIANG Qi, WU Ke, SHE Cheng, TANG Ruiyi, LIU Na, LI Jie, LAN Lan
doaj   +1 more source

Endophyte‐induced systemic spatial reprogramming of metabolism in Populus trichocarpa roots under drought

open access: yesNew Phytologist, Volume 251, Issue 1, Page 438-454, July 2026.
Summary Beneficial, facultative endophytes help plants thrive in challenging environments by altering their host's metabolism, but how these cellular scale metabolic changes propagate to the systems biology scale is unknown. In this work, we employed a high‐resolution chemical imaging approach to map metabolic changes at the Populus trichocarpa root ...
Jayde Aufrecht   +9 more
wiley   +1 more source

Crystal Structure and Conformational Dynamics of N─N Bond‐Forming Piperazate Synthase

open access: yesChemBioChem, Volume 27, Issue 12, 26 June 2026.
Piperazate synthases (PZSs) catalyze the key N─N bond formation in the biosynthesis of the rare amino acid piperazic acid. X‐ray crystal structures of apo‐ and holo‐SbPZS show a dimeric enzyme with two heme‐containing active sites, where histidine residues coordinate the iron centers.
Nikita Pal   +7 more
wiley   +1 more source

Ultra-performance hydrophilic interaction liquid chromatography coupled with tandem mass spectrometry for simultaneous determination of allopurinol, oxypurinol and lesinurad in rat plasma: Application to pharmacokinetic study in rats.

open access: yesPLoS ONE, 2019
A fixed dose combination of lesinurad and allopurinol has been recently approved by USFDA and EMA for treatment of gout-associated hyperuricemia in patients who have not achieved target serum uric acid levels with allopurinol alone.
Muzaffar Iqbal   +3 more
doaj   +1 more source

Advances in Eco‐Friendly Extraction of Fruit Bioactive Compounds: Technologies, Challenges and Future Directions

open access: yesAnalytical Science Advances, Volume 7, Issue 1, June 2026.
Fruit bioactive compounds offer antioxidant, anti‐inflammatory, and preventive benefits, yet extraction is hindered by poor solubility and conventional methods using toxic solvents and high energy. This review evaluates traditional and advanced eco‐friendly technologies, highlighting efficiency, selectivity, and sustainability.
Abadi Gebreyesus Hndeya   +2 more
wiley   +1 more source

Chemical Straightening as a Source of Analytical Variability in Hair Testing: A Dual‐Analyte Case Report

open access: yesDrug Testing and Analysis, Volume 18, Issue 6, Page 771-776, June 2026.
Permanent chemical hair straightening was associated with analyte‐dependent changes in hair concentrations, showing increased endogenous GHB levels and decreased alprazolam concentrations after treatment. These results suggest that chemical hair straightening procedures may influence hair concentrations and should be considered when interpreting hair ...
Miriam Blanco‐Ces   +5 more
wiley   +1 more source

Deglacial Permafrost Organic Carbon Delivery at the Northern Svalbard Continental Margin: Insights From Tetraether Lipids and Plant Biomarkers

open access: yesJournal of Geophysical Research: Biogeosciences, Volume 131, Issue 6, June 2026.
Abstract Degradation of Arctic permafrost due to global warming and sea level rise could trigger positive feedbacks, exacerbating climate change. However, uncertainties remain on how permafrost systems may respond because we lack a complete understanding of the permafrost‐climate feedback.
Mathia Sabino   +6 more
wiley   +1 more source

Urate‐Related Genetic Risk Modulates the Anti‐Aging Effects of Exogenous Nucleotides: Multi‐Omics Evidence From Older Adults

open access: yesAging Cell, Volume 25, Issue 6, June 2026.
In the TALENTs trial, 19‐week exogenous nucleotide supplementation produced UA‐PRS‐dependent anti‐aging responses: reduced DNA methylation age in High‐PRS individuals and preserved telomere length with improved immune–inflammatory profiles in Low‐PRS individuals, supporting precision nutrition for healthy aging.
Ruisheng Fu   +6 more
wiley   +1 more source

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