Results 151 to 160 of about 56,542 (314)
Journal of Quaternary Science, EarlyView.ABSTRACT While competition with large carnivores is likely to have shaped Middle Paleolithic hominins' subsistence behavior, palimpsested human and carnivore accumulations render the signal challenging to isolate. This study presents a detailed zooarchaeological and taphonomic analysis of a non‐anthropogenic faunal assemblage from a MIS 5 (~130–80 ka ...
Meir Orbach +4 more
wiley +1 more source
Interplanetary frontiers: terraforming from an invasion science perspective
Oikos, EarlyView.The pursuit of a multi‐planetary existence represents one of humanity's greatest frontiers. If applied justly, it offers an opportunity to extend its civilization's lifespan amid escalating sustainability crises on Earth. One approach increasingly gaining traction is terraforming, a hitherto theoretical ecological and evolutionary experiment revolving ...
Teun Everts +2 more
wiley +1 more source
More than proteins for empty stomachs: Wild meat in the BaTonga food system
People and Nature, EarlyView.Abstract Our paper highlights the limitations of the framework used by many conservation‐focused programmes that incorporate food security objectives. This framework encourages the substitution of wild proteins with domestic proteins by promoting animal farming in communities located near conservation areas.
Muriel Figuié +5 more
wiley +1 more source
Discovery of a ‘Grail-Shaped’ Drug: Ne-ratinib and the Downregulation of Mutant RAS
European Medical Journal Oncology, 2019 It has been stated that developing a drug that can attack mutated RAS proteins is ‘the Holy Grail’ of cancer therapeutics. Through a series of unexpected findings, the authors discovered that the irreversible epidermal growth factor receptor 1/2/4 ...
Paul Dent +2 more
doaj
People and Nature, EarlyView.Abstract The town of Gamba in southwest Gabon represents an exceptional example of how the development of an extractive industry (in this case oil production) may impact wild meat consumption in an area of global importance for biodiversity. Studies in the 1990s identified an active wild meat trade; however, no studies have been undertaken since, and ...
James McNamara +4 more
wiley +1 more source
The genetic mechanisms that allow organisms to incorporate information from the environment into developmental programs that control size, shape and color are important to identify in order to more fully understand developmental plasticity and adaptation
Gudmunds, Erik, +4 more
core
Genetic analysis of primary lung interdigitating dendritic cell sarcomas
The Journal of Pathology, EarlyView.Abstract Interdigitating dendritic cell sarcomas (IDCSs) are rare tumors that commonly arise in the hematopoietic system and rarely outside. The genetic drivers of IDCS carcinogenesis are unknown; therefore, therapeutic options are limited. We investigated somatic gene mutations and copy‐number alterations (CNAs) in nine IDCSs arising in the lung by ...
Mikhail S Ermakov +6 more
wiley +1 more source
Pediatric Discovery, EarlyView.MSC‐Exo derived from human umbilical cord (HucMSC‐Exo) downregulates INHBA expression, consequently modulating the PI3K/AKT signaling cascade. This regulation attenuates renal fibroblast activation and extracellular matrix deposition, thereby exerting a renoprotective effect against fibrosis.
Meiling Chen +11 more
wiley +1 more source
Strategies for Assessing Post‐Wildfire Geomorphic Resilience in Semiarid Rivers
River Research and Applications, EarlyView.ABSTRACT We review and summarize diverse components of a catchment that can be monitored after wildfire to assess the geomorphic resilience of the river corridor in semiarid regions. We distinguish upland portions of river catchments from river corridors.
Ellen Wohl +8 more
wiley +1 more source