ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source
NEDD8 Promotes the Progression and Inflammation of Keratoconus by Increasing the Expression of YAP1. [PDF]
Qu J +5 more
europepmc +1 more source
Surgical Management of Non‐Allergic Rhinitis—An EAACI Task Force Position Paper
ABSTRACT Non‐allergic rhinitis is a frequent yet underdiagnosed cause of chronic nasal symptoms, including nasal congestion, rhinorrhoea, and upper airway hyperreactivity. Its pathophysiology involves neurogenic dysregulation, leading to excessive mucus production and vasodilation.
Marie Lundberg +18 more
wiley +1 more source
The Hippo tumor suppressor pathway triggers non-cell autonomous tumorigenesis in Drosophila. [PDF]
Honda D +7 more
europepmc +1 more source
Adolescents' Experiences of Weight‐Related Bullying in the School Setting—A Qualitative Study
ABSTRACT Aim Obesity is a stigmatised disease, and weight‐related bullying is the most common form of victimisation. This study aimed to provide a nuanced understanding of adolescents’ experiences of such victimisation and related interventions. Methods Data were collected between April and October 2025 through semi‐structured interviews and analysed ...
Emelie Andersson +2 more
wiley +1 more source
Canonical and noncanonical Hippo signaling in C. elegans. [PDF]
Huynh L +4 more
europepmc +1 more source
Morphometric and Paleobiological Insights Into Pleistocene Sicilian Wolf Populations
ABSTRACT The Pleistocene wolves (Canis lupus) from Sicily represent one of the few known insular populations of this species from that time period. Despite their potential relevance for understanding carnivore adaptations in insular contexts, no dedicated study has previously investigated their morphology and evolutionary significance.
Domenico Tancredi +3 more
wiley +1 more source
Crosstalk of the Hippo/YAP pathway in the progression of oral potentially malignant disorders to oral squamous cell carcinoma: a systematic review. [PDF]
Kazemi KS +5 more
europepmc +1 more source
ABSTRACT At its core, transhumanism is utopic and apocalyptic: it tells us we will be saved through an imminent radical change of our being wrought by radical human enhancement (RHE) technologies. We are rushing, its supporters claim, towards a technological utopia so long as assorted techno‐phobes do not stand in the way.
Benjamin N. Parks
wiley +1 more source
Luteinizing hormone activates the Hippo pathway to promote progesterone synthesis in bovine luteal cells. [PDF]
Tamanaeifar F +7 more
europepmc +1 more source

