Results 171 to 180 of about 46,422 (268)

Scaffolding Supports the Hippo

Cellular and Molecular Gastroenterology and Hepatology
openaire   +2 more sources

(426) Hippo [PDF]

, 2003
openaire   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

DKK1 Suppresses Hippo Signaling via PIP₃-OGT-LRP6 <i>O</i>-GlcNAcylation in Hepatocellular Carcinoma. [PDF]

Cancer Commun (Lond)
Lee U, Eun JW, Kim T, Shim H, Choi Y, Jung H, Mo J, Kim SS, Baek GO, Yoon MG, Lee H, Lee W, Kim W, Kim J, Yi EC, Kim SU, Cheong JY, Jho EH.   +17 more
europepmc   +1 more source

Relics, writing, and devotion in early medieval Chelles

Early Medieval Europe, EarlyView.
The discovery in 1983 of a collection of relics with their medieval identificatory tags in the parish church of Chelles opened new avenues for research on devotional and writing practices in this Frankish royal foundation. This is the first systematic study of the corpus of relic labels that accompanied these sacred objects, particularly of the subset ...
Ana de Oliveira Dias
wiley   +1 more source

Hippo pathway activation drives fibrogenic remodelling in influenza A virus-infected lung fibroblasts. [PDF]

ERJ Open Res
Reisser Y, Winkler E, Hoffmann J, Kumar ND, Häder A, Lang SM, Löffler B, Deinhardt-Emmer S.   +7 more
europepmc   +1 more source

Mechanical stiffness orchestrates distinct regulation of MRTFs and YAP/TAZ transcriptional cofactors in hepatocytes

The FEBS Journal, EarlyView.
MRTFs and YAP/TAZ proteins, or mechanosensitive transcriptional cofactors (MRTcoF), regulate common genes associated with cellular contractility and immune cell infiltration. Their differential regulation in response to stiffness is linked to changes in hepatocyte's aspect ratio. MRTFB does not undergo nuclear translocation under these conditions. This
Brenda Selene Torres‐Ortiz, Daniel Pérez‐Calixto, Jorge Carretero‐Ortega, Aida Gabriela Guzman‐López, Diana Cristina Pinto‐Dueñas, Mariana Hernández‐Juárez, Alejandra Jiménez‐Escobar, Adriana Rodríguez‐Hernández, Beatriz Díaz‐Bello, Nathalia Serna‐Márquez, Miguel Ángel Peña‐Rico, Laura Gómez‐Romero, Francisco Gabriel Vázquez‐Cuevas, Genaro Vázquez‐Victorio   +13 more
wiley   +1 more source

Targeting the Hippo pathway in pulmonary arterial hypertension: emerging pharmacological strategies. [PDF]

J Hypertens
Zheng D, Guo Y.
europepmc   +1 more source

Physiological media and oxygen levels modulate cancer hallmarks in cultured breast cancer cells

The FEBS Journal, EarlyView.
MCF7 breast cancer cells were cultured in standard conditions (18% O2 and DMEM) and physiological conditions (5% O2 and Plasmax, a medium modeled after the human plasma metabolome). A combined transcriptomic and proteomic approach was used to identify gene expression signatures at the mRNA and protein levels upstream of functional enrichment analyses ...
Jacob E. Wiebe, Ricardo Alva, Fereshteh Moradi, Sarah Alderman, Ping Liang, Jeffrey A. Stuart   +5 more
wiley   +1 more source

Multidimensional Regulatory Network of <i>YAP1</i> Driving Malignant Progression in Esophageal Cancer: Molecular Mechanisms and Targeted Therapy: A Review. [PDF]

Oncol Res
Chen JH, Du SR, Liu C, Liu BB, Xu HY, Ji XY, Feng B, Ma CZ, Guo JH.   +8 more
europepmc   +1 more source