Journal of the Royal Anthropological Institute, EarlyView.Our current understanding of the origins of Homo sapiens is limited, in part, by the fragmented fossil record from Late Pleistocene and early Holocene Africa. Here, we re‐examine the Kabua 1 cranium, an enigmatic and little‐studied Kenyan fossil discovered in the 1950s. We compare virtual reconstructions created previously by our team with a wide range
Abel Marinus Bosman +7 more
wiley +1 more source
Mechanobiology of the Hippo-YAP Signaling Network. [PDF]
Cold Spring Harb Perspect BiolTripathi BK, Irvine KD.
europepmc +1 more source
Orgaangroei controle bij afwezigheid van Hippo signalering
, 2018 The evolutionarily conserved Hippo signaling pathway is considered a regulator of organ growth and size during development. This conclusion derives from the observation that Hippo pathway kinase mutation, and consequent activation of the transcription ...
Romanelli, L.
core
Journal of the Royal Anthropological Institute, EarlyView.The Eastern Mediterranean lies directly on the principal migration route for human groups dispersing across Africa, Europe, and Asia. It also encompasses the Balkans, where fauna and flora, as well as hominin populations, are thought to have persisted through glacial periods.
Katerina Harvati
wiley +1 more source
When protein stability drives tumor progression. [PDF]
Cent Eur J ImmunolTabarkiewicz J +3 more
europepmc +1 more source
Integrative Zoology, EarlyView.The transition of cetaceans from a terrestrial to an aquatic environment involved a crucial sensory adaptation to environments with limited visibility. Vibrissae, important mechanoreceptors, undergo an ontogenetic transformation in odontocetes. This research describes the histomorphology of vibrissae and crypts at different developmental stages ...
Cecilia Mariana Krmpotic +10 more
wiley +1 more source
Global Warming and Mass Extinctions Associated With Large Igneous Province Volcanism
Geophysical Monograph Series, Page 83-102., 2021 Exploring the links between Large Igneous Provinces and dramatic environmental impact
An emerging consensus suggests that Large Igneous Provinces (LIPs) and Silicic LIPs (SLIPs) are a significant driver of dramatic global environmental and biological changes, including mass extinctions.
David P. G. Bond, Yadong Sun
wiley +1 more source
Hippo-YAP/TAZ Signaling in Astrocytes and Microglia: Role in Neuroinflammation, Neurodegeneration and Glial Tumors. [PDF]
Int J Mol SciZgorzynska E.
europepmc +1 more source
Transcriptomics Unveil Dsx1 as a Critical Regulator in Sexual Dimorphism of Crustaceans
Integrative Zoology, EarlyView.Sexually dimorphic traits are involved in reproductive competition and are shaped by sex‐biased gene expression. This study identifies Dsx1 as a key male‐biased gene in Morinoia aosen and demonstrates through RNA interference that its disruption feminizes male‐specific T3 leg structures.
Yan Tong +8 more
wiley +1 more source
Allergy, EarlyView.ABSTRACT In the last decades, critical advancements in research technology and knowledge on disease mechanisms steered therapeutic approaches for chronic inflammatory diseases towards unprecedented target specificity. For allergic and chronic lung diseases, biologic drugs pioneered this goal, acquiring on the way—through the clinical use of monoclonal ...
F. Roth‐Walter +20 more
wiley +1 more source