Results 201 to 210 of about 56,542 (314)

Kdf1 missense mutation caused enamel defects by disrupting cell adhesion and Hippo-YAP signaling in dental epithelium. [PDF]

Int J Oral Sci
Li P, Zeng R, Xue J, Song Y, Wu J, Zeng B, Lin L, Yu D, Zhao W.   +8 more
europepmc   +1 more source

Decreased Expression of FAT4 Promotes Multiple Myeloma Proliferation and Migration by Targeting the Hippo/YAP Pathway

Cancer Science, EarlyView.
This study provides the first comprehensive characterization of the functional impact, and mechanistic role of FAT4 in MM. Our findings highlight the tumor‐suppressive role of FAT4 in MM and uncover a novel mechanism by which FAT4 regulates the Hippo/YAP pathway.
Lina Zhang, Na Shen, Xin Cheng, Qinglin Shi, Lijuan Chen, Xuxing Shen   +5 more
wiley   +1 more source

Hippo-YAP Signaling Drives Epigenetic Vulnerability in the Diabetic Heart via the miR-22-3p-SIRT1 Axis: Linking Metabolic Stress to Chromatin Control. [PDF]

Diabetes
Jankauskas SS, Varzideh F, Santulli G.
europepmc   +1 more source

Patch Testing in Paediatric Drug Hypersensitivity Reactions: Current Evidence and Clinical Implications

Contact Dermatitis, EarlyView.
ABSTRACT Drug hypersensitivity reactions (DHRs) are common in children and are diagnostically challenging, with cutaneous manifestations being the most common presentation. Patch testing (PT) is a well‐established tool for investigating delayed T‐cell‐mediated reactions and is widely used in patients with contact dermatitis.
Gabriele Simonetti, Francesco Catamerò, Giulia Liccioli, Leonardo Tomei, Simona Barni, Mattia Giovannini, Lucrezia Sarti, Francesca Mori   +7 more
wiley   +1 more source

miR-927 Regulates Photoreceptor Subtype Specification Through Yorkie and Sensory Opsins in <i>Drosophila</i>. [PDF]

Cells
Ji H, Zhang S, Lu H, Ma R, Xin F, Che J, Wu H, Wang G, Xie B.   +8 more
europepmc   +1 more source

Impact of G‐CSF on Donor TCR Clonal Diversity and T Cell Function During Donor HSC Mobilisation

Cell Proliferation, EarlyView.
In this study, we found that G‐CSF mobilisation caused a reduction in TCR clonal diversity and down‐regulation of T‐cell function in donors. This may be one of the reasons for the low incidence of GVHD mediated by G‐CSF after allo‐HSCT. Source: Created in BioRender. Li https://BioRender.com/otownki.
Xinye Li, Zhixi Chen, Jie Chen, Xingwei Zhang, Jiamian Zheng, Zirui Liu, Meixue Pan, Yue Li, Bo Yu, Shaohua Chen, Jing Lai, Xianfeng Zha, Liye Zhong, Yikai Zhang, Yangqiu Li   +14 more
wiley   +1 more source

The Regulation and Function of Hippo/YAP Pathway in Cancer. [PDF]

FASEB J
Ghosh C, Kakar R, Torkamboor S, Sun Y.
europepmc   +1 more source

Lactate‐Primed NETosis Modulates Hepatic Regeneration During Acute Liver Failure via the TLR9/KLF15/AJUBA Axis

Cell Proliferation, EarlyView.
This study elucidates a novel Kupffer cell‐neutrophil‐hepatocyte axis that drives metabolic‐immune crosstalk during acute liver failure. Specifically, lactate‐primed NETs release links metabolic reprogramming to NETosis‐induced regenerative failure in hepatocytes via the TLR9/KLF15/AJUBA axis.
Jin Guo, Xiaoya Zhang, Danmei Zhang, Chunxia Shi, Luwen Wang, Zuojiong Gong   +5 more
wiley   +1 more source

DKK1 Suppresses Hippo Signaling via PIP₃-OGT-LRP6 <i>O</i>-GlcNAcylation in Hepatocellular Carcinoma. [PDF]

Cancer Commun (Lond)
Lee U, Eun JW, Kim T, Shim H, Choi Y, Jung H, Mo J, Kim SS, Baek GO, Yoon MG, Lee H, Lee W, Kim W, Kim J, Yi EC, Kim SU, Cheong JY, Jho EH.   +17 more
europepmc   +1 more source

Limited elephant impacts on baobabs despite increasing elephant densities in a newly established protected area

Conservation Science and Practice, EarlyView.
Researchers combined aerial and ground surveys to map baobab distribution and assess elephant herbivory impacts on baobabs across Karingani Game Reserve, Mozambique. Researchers found that aerial surveys were an effective tool for mapping baobabs and that baobabs were more likely to occur closer to permanent water, at lower elevations, and in areas ...
Audrey Y. Chin, Catherine A. Ressijac, Peter S. Goodman, Hannah Adler, Andrew B. Davies   +4 more
wiley   +1 more source