Results 221 to 230 of about 46,422 (268)
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Sugar defeats the Hippo: Glycogen regulation of the Hippo pathway in liver
Molecular Cell, 2021Liver glycogen is famous for glucose storage, but new work by Liu et al. (2021) now reveals that it's been hiding a few secrets and can directly promote liver enlargement and tumorigenesis by sequestering the tumor-suppressive Hippo signaling pathway.
Anh Thu, Nguyen-Lefebvre +2 more
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Proceedings of the VLDB Endowment, 2022
Hyper-parameter optimization is crucial for pushing the accuracy of a deep learning model to its limits. However, a hyper-parameter optimization job, referred to as a study, involves numerous trials of training a model using different training knobs, and therefore is very computation-heavy, typically taking hours and days to finish.
Ahnjae Shin +4 more
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Hyper-parameter optimization is crucial for pushing the accuracy of a deep learning model to its limits. However, a hyper-parameter optimization job, referred to as a study, involves numerous trials of training a model using different training knobs, and therefore is very computation-heavy, typically taking hours and days to finish.
Ahnjae Shin +4 more
openaire +1 more source
The Hippo in the room: Targeting the Hippo signalling pathway for osteosarcoma therapies
Journal of Cellular Physiology, 2020AbstractOsteosarcoma (OS) is a primary malignant bone tumour which usually occurs in children and adolescents. OS is primarily a result of chromosomal aberrations, a combination of acquired genetic changes and, hereditary, resulting in the dysregulation of cellular functions.
Emel Rothzerg +5 more
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Anti-Cancer Drugs, 2017
The Hippo pathway has generated considerable interest in recent years because of its involvement in several key hallmarks of cancer progression and metastasis. Research on the Hippo signaling pathway in cancer has been used to determine the activity of yes-associated protein (YAP) in tumorigenesis and disease progression.
Jingwen, Cao, Wenlong, Huang
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The Hippo pathway has generated considerable interest in recent years because of its involvement in several key hallmarks of cancer progression and metastasis. Research on the Hippo signaling pathway in cancer has been used to determine the activity of yes-associated protein (YAP) in tumorigenesis and disease progression.
Jingwen, Cao, Wenlong, Huang
openaire +2 more sources
Angelaki, 2017
This article explores the formation of a tranimal, hippopotamus alter-ego. Confronting transgender with transpecies, the author claims that his hippopotamus “identity” allowed him to (verbally) escape, all at once, several sets of categorization that govern human bodies (“gender,” “sexuality,” age).
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This article explores the formation of a tranimal, hippopotamus alter-ego. Confronting transgender with transpecies, the author claims that his hippopotamus “identity” allowed him to (verbally) escape, all at once, several sets of categorization that govern human bodies (“gender,” “sexuality,” age).
openaire +2 more sources
Blood, 2010
In this issue of Blood , Hartmann and colleagues report on the results of a high-resolution genomic profiling study in a large series of MCL. Copy number alteration and expression data are amalgamated with clinical outcome. Their data confirm the critical role of the cell-cycle and DNA damage-
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In this issue of Blood , Hartmann and colleagues report on the results of a high-resolution genomic profiling study in a large series of MCL. Copy number alteration and expression data are amalgamated with clinical outcome. Their data confirm the critical role of the cell-cycle and DNA damage-
openaire +2 more sources
Under the hammer; Hippo, hippo hurray!
Fundraising for Schools, 2009Angela Youngman explains how one school in Norfolk organised a fundraising auction that got the whole town involved.
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Science Signaling, 2011
The kinase Tao-1 promotes activation of the Hippo pathway.
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The kinase Tao-1 promotes activation of the Hippo pathway.
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