Results 211 to 220 of about 46,422 (268)

Integrating natural baselines into ecosystem restoration: scaling herbivore targets for European landscapes

Restoration Ecology, EarlyView.
Abstract Introduction Herbivore‐mediated ecosystem processes are fundamental to biodiversity, yet have been greatly diminished by megafauna extinctions and replacement of wild herbivores by managed livestock. With increasing restoration ambitions—including the United Nations' (UN) Decade on Ecosystem Restoration and the European Union (EU) Nature ...
Camilla Fløjgaard, Robert Buitenwerf, Alessandro Chiarucci, Martin Konvička, Rasmus Mohr Mortensen, Norman Owen‐Smith, Deli Saavedra, Jens‐Christian Svenning, Rasmus Ejrnæs   +8 more
wiley   +1 more source

Ovarian hormone loss modifies the nucleic acid cargo of circulating extracellular vesicles and skeletal muscle metabolism after acute exercise in rats

Experimental Physiology, EarlyView.
Abstract Loss of ovarian hormones (i.e., menopause) leads to negative effects on metabolic health. While exercise offers significant benefits, it seems to be insufficient to completely reverse these changes. The mechanisms by which exercise conveys the effects throughout the body are still poorly understood.
Veera Puumalainen, Anni Maja, Tia‐Marje Korhonen, Tuuli A. Nissinen, Eero Hulkko, Janne A. Ihalainen, Maarit Lehti, Sira Karvinen   +7 more
wiley   +1 more source

EGFR-19del nuclear translocation increases HDAC7 expression inhibiting the Hippo pathway and exacerbating TKI resistance in lung adenocarcinoma. [PDF]

Theranostics
Feng Y, Wang M, Liu Y, Wu X, Lin X, Han Q, Rong X.   +6 more
europepmc   +1 more source

Loss of FAM60A disrupts Sin3/HDAC control of the Hippo signaling and promotes oncogenic YAP1 activation. [PDF]

Cell Death Dis
Miah M, Huda MN, Islam MR, Gerald D, Khator S, Saha A, Alam J, Thornton JL, Gies A, Bauer MA, Stephens KE, Nagalo BM, Rahman MA, Washburn MP, Miah S.   +14 more
europepmc   +1 more source

Integrative machine learning identifies a TEAD4-driven endothelial program shaping drug sensitivity and microvascular invasion in HCC. [PDF]

J Transl Med
Zhang P, Song H, Lin S, Zhu Y.
europepmc   +1 more source

Systematic analysis of hippo pathway signaling identifies TEAD1 as a transcriptional regulator of neuroendocrine prostate cancer. [PDF]

Neoplasia
Brown LG, Coleman IM, Chu TLH, Sayar E, Patel RA, Hanratty B, Adil M, Li D, Li Y, Nguyen HM, Sessions CJ, Sweeney EL, Alumkal JJ, da Costa RMG, Wang Y, Lin DW, True LD, Dumpit R, Corey E, Lee JK, Nelson PS, Xin L, Haffner MC, Morrissey C.   +23 more
europepmc   +1 more source

The hippo-YAP1/TEAD1-SLC7A5 axis: uncovering a novel therapeutic target for oxalate-induced renal tubular ferroptosis. [PDF]

Redox Rep
Yang J, Ma Z, Wan W, Yuan D, Li J, Wang Y, Wang B, Lyu G, Xun Y, Yu X.   +9 more
europepmc   +1 more source

DNA-based characterization of primary hepatic MALT lymphoma reveals a rare FAT3 missense variant and Hippo pathway activation: a case report and literature review. [PDF]

World J Surg Oncol
Zhang R, Zhang C, Bai Z, Zhang Y, Wei F, Zhang A.   +5 more
europepmc   +1 more source

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Immuno-hippo: Research progress of the hippo pathway in autoimmune disease

Immunology Letters, 2021
Extensive research in Drosophila and mammals has identified the core components of Hippo signaling, which controls gene expression. Studies of Drosophila have demonstrated the highly conserved Hippo pathway controls tissue homeostasis and organ size by regulating the balance between cell proliferation and apoptosis.
Paipai, Guo, Zhen, Wang, Zhengwei, Zhou, Yu, Tai, Aijun, Zhang, Wei, Wei, Qingtong, Wang   +6 more
openaire   +2 more sources