Results 11 to 20 of about 120,668 (359)
Proceedings of the VLDB Endowment, 2022 Hyper-parameter optimization is crucial for pushing the accuracy of a deep learning model to its limits. However, a hyper-parameter optimization job, referred to as a study, involves numerous trials of training a model using different training knobs, and therefore is very computation-heavy, typically taking hours and days to finish.
Ahnjae Shin +4 more
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Cold Spring Harbor Perspectives in Biology, 2012 The Hippo pathway regulates tissue growth, and inactivation of any of four key components (HPO, WTS, SAV, and MATS) results in tissue overgrowth. Cell junctions may also modulate the pathway's activity.
Kieran F, Harvey, Iswar K, Hariharan
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Genes & Development, 2011 The Hippo pathway coordinates organ size and cell proliferation. The retinoblastoma family of proteins regulates progression through the G0/G1 phase of the cell cycle. Disruption of either pathway contributes to cancer formation. Three recent studies in Genes & Development reveal how cellular proliferation is coordinated between these pathways ...
Dick, Frederick A., Mymryk, Joe S.
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eLife, 2020 The intermediate filament protein keratin 14 (K14) provides vital structural support in basal keratinocytes of epidermis. Recent studies evidenced a role for K14-dependent disulfide bonding in the organization and dynamics of keratin IFs in skin ...
Yajuan Guo +6 more
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Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]
, 2017 The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca +12 more
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Frontiers in Oncology, 2023 IntroductionHepatocellular carcinoma (HCC) prevalence is rising annually, but the existing treatment strategies are limited; therefore, it is crucial to explore new therapeutic approaches.MethodsHere, we investigate the potential anti-cancer mechanism of
Mingyuan Tao +3 more
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Biodiversity Observations, 2019 Hippo cannibalism was observed at Mandavu reservoir in Hwange National Park, Zimbabwe.
Julio J. De Castro +3 more
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Developmental Cell, 2017 Normal organ growth requires precise signaling from key developmental pathways, as well as careful coordination between these pathways. In this issue of Developmental Cell, Pascual and colleagues (2017) investigate the dire consequences of simultaneous deregulation of both the Ras and Hippo pathways.
Taryn M, Sumabat, Iswar K, Hariharan
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Approaching Religion, 2018 Review of Tobias Churton's Deconstructioning Gurdjieff: Biography of a Spiritual Magician (Rochester, Inner Traditions, 2017).
Hippo Taatila
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Cell Death & Differentiation, 2017 The three p53 family members, p53, p63 and p73, are structurally similar and share many biochemical activities. Yet, along with their common fundamental role in protecting genomic fidelity, each has acquired distinct functions related to diverse cell autonomous and non-autonomous processes. Similar to the p53 family, the Hippo signaling pathway impacts
Noa, Furth, Yael, Aylon, Moshe, Oren
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