Results 251 to 260 of about 56,542 (314)

Born early, age fast: Consequences of premature birth on chronic disease and accelerated ageing

The Journal of Physiology, EarlyView.
Abstract figure legend ELGANs are exposed to several postnatal pro‐oxidant stressors, including ambient and supplemental oxygen, mechanical ventilation, infections, hyperalimentation, excessive glucocorticoids and intermittent hypoxia. Since endogenous antioxidant defences are underdeveloped, this imbalance promotes oxidative stress and inflammation ...
Estelle B. Gauda, Julijana Ivanovska, Dwayne Mascarenhas, Jeffrey Antwi, Atefeh Mohammadi, Bonny Jasani   +5 more
wiley   +1 more source

Integrative machine learning identifies a TEAD4-driven endothelial program shaping drug sensitivity and microvascular invasion in HCC. [PDF]

J Transl Med
Zhang P, Song H, Lin S, Zhu Y.
europepmc   +1 more source

Circular RNAs: Unlocking new avenues in cardiometabolic disease management

The Journal of Physiology, EarlyView.
Abstract figure legend In the heart circular RNAs (circRNAs) function as microRNA sponges, interact with proteins and can even undergo translation. Advances in bioinformatics now enable their identification through high‐throughput RNA sequencing, whereas computational analyses reveal differential expression in cardiac disease settings.
Kimberley M. Mellor, Thomas D. Donelly, Gerald L.M. Naepi, Glenn D. Wadley, Bianca C. Bernardo   +4 more
wiley   +1 more source

YAP inactivation-mediated autophagy inhibition contributes to cisplatin resistance in ovarian cancer cells. [PDF]

J Ovarian Res
Nguyen NT, Hsieh MR, Nguyen HDH, Chimphlee W, Visitsattapongse S, Chiu WT.   +5 more
europepmc   +1 more source

Vascular smooth muscle cell mechanotransduction: Pathways, phenotypes and emerging technologies

The Journal of Physiology, EarlyView.
Abstract figure legend Vascular smooth muscle cells are exposed to mechanical stimuli from the blood flow and the extracellular matrix. The cells sense the signals from cyclic stretch, shear stress, hydrostatic pressure and matrix stiffness through specialized mechanosensors, such as mechanosensitive ion channels or cell surface receptors including ...
Nivethitha Kota Lakshminaraasimulu, Rachel E. A. Smyth, Aishwarya Prakash, Thomas Iskratsch   +3 more
wiley   +1 more source

aPKC and F-actin dynamics promote Hippo pathway polarity in asymmetrically dividing neuroblasts. [PDF]

Biol Open
Joshi NS, Sullivan VM, Tokamov SA, Fehon RG.   +3 more
europepmc   +1 more source

Engineered microtissue systems for identifying the roles of Wnt and YAP signaling in hepatoblast differentiation and organization. [PDF]

Mater Today Bio
Grenci B, Tsai A, Zobus K, Underhill GH.
europepmc   +1 more source

DNA-based characterization of primary hepatic MALT lymphoma reveals a rare FAT3 missense variant and Hippo pathway activation: a case report and literature review. [PDF]

World J Surg Oncol
Zhang R, Zhang C, Bai Z, Zhang Y, Wei F, Zhang A.   +5 more
europepmc   +1 more source

Jianpi Jiedu Xiaozheng Fang Regulates Hepatocellular Carcinoma Proliferation and Metastasis Based on Network Pharmacology. [PDF]

J Cell Mol Med
Li B, Shi HQ, Luo R, Zhang ZQ, Dong XC, Li XH, Ye SQ, Zhong C.   +7 more
europepmc   +1 more source

Histidine phosphorylation of NME1 regulates the Hippo pathway via the ARHGAP17-CDC42-cytoskeleton axis. [PDF]

Life Med
Liu X, Chen Z, Zhu J, Deng S, Zhou Z, Ma W, Songyang Z.   +6 more
europepmc   +1 more source