Results 51 to 60 of about 46,422 (268)

Activity and Pool Use in Relation to Temperature and Water Changes in Zoo Hippopotamuses (Hippopotamus amphibious)

Animals, 2020
In the wild, hippopotamuses spend much of their daily activity in the water. In zoos, it is less clear the extent to which hippos spend time in the water.
Eduardo J. Fernandez, Martin Ramirez, Nancy C. Hawkes   +2 more
doaj   +1 more source

Using Big Data analytics tool to influence decision-making in higher education: A case of South African Technical and Vocational Education and Training colleges

South African Journal of Information Management, 2022
Background: Big data analytics in education is a new concept that has the potential to change the decision-making landscape in South African Colleges. Higher institutions of learning, including Technical and Vocation Education Training (TVET) colleges ...
Kleinbooi T. Selowa, Appolonia I. Ilorah, Sello N. Mokwena   +2 more
doaj   +1 more source

Ultrathin Hydrogel Membranes Inspired by Soap Films Enable Physiologically Relevant Breathing Lung Models

Advanced Materials, EarlyView.
A soap‐film inspired strategy enables the fabrication of ultrathin yet robust GelMA‐PAAm membranes for breathing lung culture. The hydrogel membrane supports long‐term cyclic deformation under air‐liquid interface conditions, enabling physiologically relevant breathing motions of engineered lung tissue culture. ABSTRACT Breathing continuously stretches
Yunji Lee, Gwang Myeong Kim, Wookyeom Kim, Fenny Soetanto, Gyungin Ryu, Taehun Chung, Youn Soo Kim, Junmin Lee, Hwa‐Rim Lee, Sungjune Jung   +9 more
wiley   +1 more source

Engineering Pluripotent Stem Cells‐Derived Inner Ear Organoids With Enhanced Maturation and Reproducibility by Micro‐Topographical Cues

Advanced Materials, EarlyView.
Micro‐topographical cues applied through temporally controlled microscale confinement improve the reproducibility, spatial organization, and neurosensory‐associated features of pluripotent stem cell‐derived inner ear organoids. Integration with a vascularized organoid platform further enables controlled investigation of vascular‐epithelial interactions
Harshita Sharma, Jungeun Lim, Woochan Kim, Yeon Ju Kim, Dream Kim, Shinyull Lee, Chaeyeon Park, Stephen Rhee, Shruthy Kuttapan, Jungho Ha, Sang Wook Park, Kyunghoon Kim, Noo Li Jeon, Sunho Park, Yun‐Hoon Choung, Jangho Kim   +15 more
wiley   +1 more source

Ecofeminism and Cultural-Value System in Traditional Paddy Farming: A Folklore from West Borneo

Celt: A Journal of Culture, English Language Teaching & Literature
Ne’ Balungkur represents the inherited living value of traditional paddy farming lived by Dayak Kanayatn. Concerning the ecofeminism ideology, this study aims to reveal the existence of women and nature in traditional paddy farming in Ne’ Balungkur ...
Antonius Setyawan Sugeng Nur Agung, Monika Widyastuti Surtikanti, Wedhowerti Wedhowerti   +2 more
doaj   +1 more source

A Genetic Screen Reveals an Unexpected Role for Yorkie Signaling in JAK/STAT-Dependent Hematopoietic Malignancies in Drosophila melanogaster

G3: Genes, Genomes, Genetics, 2017
A gain-of-function mutation in the tyrosine kinase JAK2 (JAK2V617F) causes human myeloproliferative neoplasms (MPNs). These patients present with high numbers of myeloid lineage cells and have numerous complications.
Abigail M. Anderson, Alessandro A. Bailetti, Elizabeth Rodkin, Atish De, Erika A. Bach   +4 more
doaj   +1 more source

Inhibition of IGFBP4 in Granulosa Cells Improves Reproductive Performance and Maintains Fertility With Age via YAP Signaling

Advanced Science, EarlyView.
IGFBP4 is upregulated in granulosa cells of aged ovaries across monkeys, mice, and humans. It inhibits YAP signaling, thereby suppressing cell proliferation and contributing to follicular dysfunction. Deletion of Igfbp4 in granulosa cells enhances ovulatory output, improves hormone profiles, and reproductive performance in aged female mice, suggesting ...
Qianhui Hu, Ajun Geng, Ziyuan Li, Fanghao Guo, Jingqiang Wang, Xinyi Chen, Meiling Zhang, Yi Arial Zeng, Wen Li   +8 more
wiley   +1 more source

Mood Disorder Severity and Subtype Classification Using Multimodal Deep Neural Network Models

Sensors
The subtype diagnosis and severity classification of mood disorder have been made through the judgment of verified assistance tools and psychiatrists.
Joo Hun Yoo, Harim Jeong, Ji Hyun An, Tai-Myoung Chung   +3 more
doaj   +1 more source

The Role of Mst1 in Lymphocyte Homeostasis and Function

Frontiers in Immunology, 2018
The Hippo pathway is an evolutionarily conserved pathway crucial for regulating tissue size and for limiting cancer development. However, recent work has also uncovered key roles for the mammalian Hippo kinases, Mst1/2, in driving appropriate immune ...
Jiali Cheng, Yukai Jing, Danqing Kang, Lu Yang, Jingwen Li, Ze Yu, Zican Peng, Xingbo Li, Yin Wei, Quan Gong, Quan Gong, Richard J. Miron, Yufeng Zhang, Chaohong Liu   +13 more
doaj   +1 more source

Genome‐Wide CRISPR Screen Identifies a microRNA Orchestrating Pleiotropic Resistance to Targeted Therapy and T Cell Immunity in Melanoma

Advanced Science, EarlyView.
A genome‐wide microRNA CRISPR screen identifies miR‐18a as a master regulator of cross‐resistance in melanoma. Loss of miR‐18a activates the AJUBA–YAP/Hippo axis to confer BRAFi resistance and enhances THBS1–CD47 interaction to impair CD8+ T cell immunity. hnRNP A1 is identified as an upstream regulator of miR‐18a processing.
Zhao Wang, Haotian Liu, Xueqi Wang, Jianjin Teng, Zihan Zheng, Jingya Zhang, Wanyi Xiao, Qian Liang, Jiaxin Li, Xiaomeng Jia, Xin Feng, Hongzhang Cui, Menghan Luo, Tielong Yang, Liuxing Wu, Ke Zhao, Weilong Yang, Mulin Jun Li, Dandan Huang, Jilong Yang   +19 more
wiley   +1 more source