Results 231 to 240 of about 990,791 (254)

Human umbilical cord mesenchymal stem cell-derived exosomes act via the miR-1263/Mob1/Hippo signaling pathway to prevent apoptosis in disuse osteoporosis.

Biochemical and Biophysical Research Communications - BBRC, 2020
Disuse osteoporosis (DOP) is a common complication resulting from the lack of or disuse of mechanical loading and has been unsatisfactorily treated. We hypothesized that exosomes derived from human umbilical cord mesenchymal stem cells (HUCMSCs) could ...
Baocheng Yang, Ming‐jie Kuang, Jia-yu Kang, Jie Zhao, Jian-xiong Ma, Xin-long Ma   +5 more
semanticscholar   +1 more source

Discovery of tertiary amide derivatives incorporating benzothiazole moiety as anti-gastric cancer agents in vitro via inhibiting tubulin polymerization and activating the Hippo signaling pathway.

European journal of medicinal chemistry, 2020
On the basis and continuation of our previous studies on anti-tubulin and anti-gastric cancer agents, novel tertiary amide derivatives incorporating benzothiazole moiety were synthesized and the antiproliferative activity was studied in vitro ...
Jian Song, Qiu-Lei Gao, Bo-Wen Wu, Ting Zhu, X. Cui, Cheng-Jun Jin, Shu-Yu Wang, Sheng-Hui Wang, Dong-Jun Fu, Hong-min Liu, Sai-Yang Zhang, Yan-Bing Zhang, Yongchun Li   +12 more
semanticscholar   +1 more source

Silence of lncRNA MIAT-mediated inhibition of DLG3 promoter methylation suppresses breast cancer progression via the Hippo signaling pathway.

Cellular Signalling, 2020
As the foremost common female malignancy, breast cancer (BC) poses a significant public health stumbling block. Although treatment protocols have improved over the years, the overall prognosis of BC remains unsatisfactory.
Dezhi Li, Xingsheng Hu, Sijia Yu, Shishan Deng, Min Yan, Fengfei Sun, Junmei Song, L. Tang   +7 more
semanticscholar   +1 more source

Regulation of Hippo signaling pathway in cancer: A MicroRNA perspective.

Cellular Signalling, 2020
Recent studies have suggested that Hippo signaling is not only involved in controlling organ size in Drosophila but can also regulate cell proliferation, tissue homeostasis, differentiation, apoptosis and regeneration.
Priyanka Samji, M. K. Rajendran, Vidya P. Warrier, Akshayaa Ganesh, Karunagaran Devarajan   +4 more
semanticscholar   +1 more source

Targeting Hippo signaling pathway by phytochemicals in cancer therapy.

Seminars in Cancer Biology, 2020
The current era of cancer research has been continuously advancing upon identifying novel aspects of tumorigenesis and the principal mechanisms behind the unleashed proliferation, invasion, drug resistance and immortality of cancer cells in hopes of ...
M. Moloudizargari, M. Asghari, S. Nabavi, D. Gulei, I. Berindan‐Neagoe, A. Bishayee, S. Nabavi   +6 more
semanticscholar   +1 more source

The role of Hippo signaling pathway and mechanotransduction in tuning embryoid body formation and differentiation

Journal of Cellular Physiology, 2020
Embryoid bodies (EBs) are the three‐dimensional aggregates of pluripotent stem cells that are used as a model system for the in vitro differentiation. EBs mimic the early stages of embryogenesis and are considered as a potential biomimetic body in tuning
A. Barzegari, V. Gueguen, Y. Omidi, A. Ostadrahimi, M. Nouri, G. Pavon-Djavid   +5 more
semanticscholar   +1 more source

SGLT2 promotes pancreatic cancer progression by activating the Hippo signaling pathway via the hnRNPK-YAP1 axis.

Cancer Letters, 2021
Dianyun Ren, Yan Sun, Dan Zhang, Dan Li, Zhiqiang Liu, Xin Jin, Heshui Wu   +6 more
semanticscholar   +1 more source

The Role of Hippo Signaling Pathway in the Development of the Nervous System

Developmental Neuroscience, 2021
Xifan Li, Kaixuan Li, Yu Chen, Fang Fang
semanticscholar   +1 more source

Hippo Signaling: A Stress Response Pathway in Stem Cells

Current Stem Cell Research and Therapy, 2021
Dilara Zeybek, Esra Buber
exaly  

Ca2+ signaling and the Hippo pathway: Intersections in cellular regulation

Cellular Signalling, 2023
Samar Sayedyahossein, David Sacks
exaly