Results 61 to 70 of about 101,099 (274)

Reduction of adult hippocampal neurogenesis modifies brain functional connectivity and enhances cocaine-seeking in mice [PDF]

, 2015
Recently, adult hippocampal neurogenesis has been proposed as a putative neuroplastic mechanism involved in those behavioural processes. In this work, we studied the effect of the inhibition of adult hippocampal neurogenesis using the DNA alkylating ...
Blanco, Eduardo, Castilla-Ortega, Estela, Estivill-Torrús, Guillermo, Ladrón de Guevara-Miranda, David, Pavón, Francisco, Pedraz, María, Rodriguez de Fonseca, Fernando, Santin-Nuñez, Luis Javier, Serrano, Antonia   +8 more
core  

Meditation effects within the hippocampal complex revealed by voxel-based morphometry and cytoarchitectonic probabilistic mapping. [PDF]

, 2013
Scientific studies addressing anatomical variations in meditators' brains have emerged rapidly over the last few years, where significant links are most frequently reported with respect to gray matter (GM).
Gaser, Christian, Kurth, Florian, Luders, Eileen, Narr, Katherine L, Toga, Arthur W   +4 more
core   +2 more sources

Intermittent fasting increases adult hippocampal neurogenesis [PDF]

Brain and Behavior, 2019
AbstractIntroductionIntermittent fasting (IF) has been suggested to have neuroprotective effects through the activation of multiple signaling pathways. Rodents fasted intermittently exhibit enhanced hippocampal neurogenesis and long‐term potentiation (LTP) at hippocampal synapses compared with sedentary animals fed an ad libitum (AL) diet. However, the
Sang‐Ha Baik, Vismitha Rajeev, David Yang‐Wei Fann, Dong‐Gyu Jo, Thiruma V. Arumugam   +4 more
openaire   +3 more sources

Taurocholic Acid Is Associated With Disturbed Functional Connectivity in the Hippocampus of Patients With Depression

Advanced Science, EarlyView.
This study identifies elevated taurocholic acid (TCA) in Major Depressive Disorder patients. Gut microbiome‐associated TCA impairs hippocampal neurogenesis, triggers microglia activation, and elicits depression‐like behavior in mice via the S1PR2. In patients, functional neuroimaging reveals that serum TCA levels correlate with altered functional ...
Xiaoying Cai, Taipeng Sun, Mengzhen Feng, Gang Chen, Junchi Zhou, Hong Zhuang, Dan Wang, Ying Chen, Zhen Cheng, Zhi Xu, Xiao Zheng, Xueli Zhang, Yonggui Yuan   +12 more
wiley   +1 more source

Epigenetics, hippocampal neurogenesis, and neuropsychiatric disorders: Unraveling the genome to understand the mind

Neurobiology of Disease, 2010
In mature, differentiated neurons in the central nervous system (CNS), epigenetic mechanisms—including DNA methylation, histone modification, and regulatory noncoding RNAs—play critical roles in encoding experience and environmental stimuli into stable ...
Jenny Hsieh, Amelia J. Eisch
doaj   +1 more source

Gamma radiation-induced impairment of hippocampal neurogenesis, comparison of single and fractionated dose regimens Deterioro de la neurogénesis en el hipocampo inducida por radiación gamma, comparación de los regímenes de dosis única y fraccionada [PDF]

, 2012
Radiation therapy of the brain is associated with many consequences, including cognitive disorders. Pathogenesis of radiation induced cognitive disorder is not clear, but reduction of neurogenesis in hippocampus may be an underlying reason. 24 adult male
Azami, N.S., Jahanshahi, M., Khoshbin khoshnazar, A.R.   +2 more
core  

Serotonin and motherhood: From molecules to mood [PDF]

, 2019
Emerging research points to a valuable role of the monoamine neurotransmitter, serotonin, in the display of maternal behaviors and reproduction-associated plasticity in the maternal brain.
Li, Ming, Lonstein, Joseph S., Pawluski, Jodi L.   +2 more
core   +3 more sources

Genetic control of hippocampal neurogenesis.

Genome biology, 2006
Adult neurogenesis in the hippocampus is under complex genetic control. A recent comparative study of two inbred mouse strains using quantitative trait locus analysis has revealed that cell survival is most highly correlated with neurogenesis and identified candidate genes for further investigation.
Pozniak, Christine D, Pleasure, Samuel J
openaire   +2 more sources

Nurr1 Orchestrates Claustrum Development and Functionality

Advanced Science, EarlyView.
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan, Andrew G. Newman, Pauline Lange, Susanne Müller, Marco Foddis, Stefan Paul Koch, Philipp Böhm‐Sturm, Maron Mantwill, Carsten Finke, Penghui Deng, Melissa Long, Dietmar Schmitz, Victor Tarabykin   +12 more
wiley   +1 more source

Current understanding and prospects for targeting neurogenesis in the treatment of cognitive impairment

Neural Regeneration Research
Adult hippocampal neurogenesis is linked to memory formation in the adult brain, with new neurons in the hippocampus exhibiting greater plasticity during their immature stages compared to mature neurons. Abnormal adult hippocampal neurogenesis is closely
Ye Liu, Xibing Ding, Shushan Jia, Xiyao Gu   +3 more
doaj   +1 more source