Results 61 to 70 of about 3,003 (174)

Effects of Natural Hirudin and Low Molecular Weight Heparin in Preventing Deep Venous Thrombosis in Aged Patients with Intertrochanteric Fracture

open access: yes, 2018
Our objective was to evaluate the efficacy and safety of natural hirudin and low molecular weight heparin (LMWH) in the prevention of perioperative deep venous thrombosis (DVT) in elderly patients with intertrochanteric fracture.
Lei Liu   +3 more
core   +1 more source

Tubular Injury in Diabetic Kidney Disease: Early Diagnosis and Intervention Strategies

open access: yesDiabetes/Metabolism Research and Reviews, Volume 41, Issue 7, October 2025.
ABSTRACT Diabetic kidney disease (DKD) is the most severe complication of diabetes mellitus and has poor prognosis, often progressing to end‐stage renal disease, causing substantial morbidity and mortality globally. While the pathogenesis of DKD has been extensively characterised, including glomerular hyperfiltration, podocyte injury, and ...
Yi Lv   +7 more
wiley   +1 more source

Bivalirudin in percutaneous coronary intervention

open access: yesVascular Health and Risk Management, 2006
Sam J Lehman, Derek P ChewDepartment of Medicine, Flinders University, South Australia, AustraliaAbstract: Bivalirudin is a member of the direct thrombin inhibitor group of anticoagulants. It has been evaluated as an alternative to unfractionated and low-
Sam J Lehman, Derek P Chew
doaj  

Cloning, Expression of Hirudin Gene from Leech (Hirudo orientalis) in BL21(DE3) Strain

open access: yes, 2017
The use of leeches in bloodletting therapy is one of the most important techniques in ancient medicine from Greek time up to now. Leeches saliva contain anticoagulant hirudin which facilitate blood flow, this is one reason for using leeches to save ...
Al-Fadal, Sabaa, Al-Badran, Adnan
core  

DALI LDL-Apheresis: Anticoagulation with R-Hirudin in a Patient with Heparin-Induced Thrombocytopenia (HIT II)

open access: yes, 2000
A 50-year old male patient with familial hypercholesterolemia and hyperlipoproteinemia (a), who underwent low density lipoprotein-apheresis treatment developed heparin-induced thrombocytopenia type II (HIT II).
E. Steinhagen-Thiessen   +3 more
core   +1 more source

Aptamer-thrombin loaded magnetic microspheres for bio-specific extraction and precise detection of hirudin

open access: yes
Hirudin, that is naturally occurring in leeches (Hirudo medicinalis) and known as the most potent natural inhibitor of thrombin, exerts double-edged effects in clinic application.
Shang, Chunqing   +13 more
core   +1 more source

A pilot trial of recombinant desulfatohirudin compared with heparin in conjunction with tissue-type plasminogen activator and aspirin for acute myocardial infarction: Results of the Thrombolysis in Myocardial Infarction (TIMI) 5 trial

open access: yes, 1994
Objectives. The purpose of this study was to assess the value of recombinant desulfatohirudin (hirudin) as adjunctive therapy to thrombolysis in acute myocardial infarction.Background. Failure to achieve initial reperfusion and reocclusion of the infarct-
Edwards, Susan J.   +14 more
core   +1 more source

Developments in antithrombotic therapy: state of the art anno 1996

open access: yes, 1996
This review aims to discuss recent developments in antithrombotic therapy. New and specific inhibitors of platelet dependent thrombosis appear to moderately improve the outcome in coronary vascular disease.
Nurmohamed, M T   +2 more
core   +1 more source

Antithrombotic therapy for acute myocardial infarction

open access: yes, 1995
Antithrombotic therapy is clearly beneficial in the treatment of acute myocardial infarction, but the optimal regimen is controversial. Treatment with aspirin leads to substantial and significant reductions in rates of mortality, reinfarction and stroke ...
O'Donnell, Christopher J.   +7 more
core   +1 more source

Reactivation of ischemic events in acute coronary syndromes: results from GUSTO-IIb

open access: yes, 2001
OBJECTIVESWe sought to determine the incidence of and risk factors for thrombotic events early after discontinuing antithrombin therapy in patients with acute coronary syndromes.BACKGROUNDDiscontinuation of treatment with heparin and other thrombin ...
Hasselblad, Vic   +19 more
core   +1 more source

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