Results 121 to 130 of about 816 (186)
Research progress on the treatment of diabetic nephropathy with leech and its active ingredients. [PDF]
Front Endocrinol (Lausanne)Tian F +6 more
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Construction of safer hirudin-derived peptides with enhanced anticoagulant properties based on C-terminal active residue adaptation and modification. [PDF]
J Adv ResYi X +6 more
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Acute subdural haemorrhage in a warfarin user following leech bite: Clinical note and review. [PDF]
Curr J NeurolDeshmukh AS +4 more
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Study on the mechanism of hirudin multi target delaying renal function decline in chronic kidney disease based on the "gut-kidney axis" theory. [PDF]
Naunyn Schmiedebergs Arch PharmacolLong C, Zhang C, Xie Y.
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Bivalirudin versus heparin in contemporary percutaneous coronary interventions for patients with acute coronary syndrome: a systematic review and meta-analysis. [PDF]
Cardiol JZhang J +5 more
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Inpharma Weekly, 1993
Hirudin is a direct thrombin inhibitor derived from leeches. Recombinant forms of hirudin are under development by a number of manufacturers, the most advanced of which are undergoing phase II clinical trials. Ciba-Geigy's desulfatohirudin [CGP 39393] and Hoechst's HBW 023 have been the agents used in a number of clinical trials to date.
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Hirudin is a direct thrombin inhibitor derived from leeches. Recombinant forms of hirudin are under development by a number of manufacturers, the most advanced of which are undergoing phase II clinical trials. Ciba-Geigy's desulfatohirudin [CGP 39393] and Hoechst's HBW 023 have been the agents used in a number of clinical trials to date.
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Thrombosis Research, 1990
The usability of recombinant hirudin as anticoagulant agent in haemodialysis was studied in nephrectomized dogs. To this end, we examined the capability of recombinant hirudin to penetrate the membranes of different capillary dialyzers used. Furthermore we investigated the pharmacokinetic behaviour of recombinant hirudin in nephrectomized dogs as well ...
E, Bucha, F, Markwardt, G, Nowak
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The usability of recombinant hirudin as anticoagulant agent in haemodialysis was studied in nephrectomized dogs. To this end, we examined the capability of recombinant hirudin to penetrate the membranes of different capillary dialyzers used. Furthermore we investigated the pharmacokinetic behaviour of recombinant hirudin in nephrectomized dogs as well ...
E, Bucha, F, Markwardt, G, Nowak
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Hirudins: Antithrombin Anticoagulants
Annals of Pharmacotherapy, 1992OBJECTIVE: To review the chemistry, pharmacology, available clinical data, and adverse effects of the hirudin anticoagulants. DATA SOURCES: A MEDLINE search and a review of recent scientific abstracts was conducted to identify pertinent literature. STUDY SELECTION: Focus was placed on studies conducted in humans.
K A, Stringer, J, Lindenfeld
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