Results 31 to 40 of about 310,272 (392)
The neuromodulator histamine is released throughout the brain during periods of wakefulness. Combined with an abundant expression of histamine receptors, this suggests potential widespread histaminergic control of neural circuit activity. However, the effect of histamine on many of these circuits is unknown.
Bolam, J. Paul, Ellender, Tommas J.
openaire +4 more sources
Psoriasis is a chronic inflammatory skin disorder characterized by hyperproliferative keratinocytes and immune cell infiltration into the skin, often accompanied by itch.
Kristine Rossbach+10 more
doaj +1 more source
The Roles of Cardiovascular H2-Histamine Receptors Under Normal and Pathophysiological Conditions
This review addresses pharmacological, structural and functional relationships among H2-histamine receptors and H1-histamine receptors in the mammalian heart.
Joachim Neumann+4 more
doaj +1 more source
Histamine and Its Receptors in the Mammalian Inner Ear: A Scoping Review
Background: Histamine is a widely distributed biogenic amine with multiple biological functions mediated by specific receptors that determine the local effects of histamine.
Lingyi Kong+2 more
doaj +1 more source
Drosophila tan Encodes a Novel Hydrolase Required in Pigmentation and Vision [PDF]
Many proteins are used repeatedly in development, but usually the function of the protein is similar in the different contexts. Here we report that the classical Drosophila melanogaster locus tan encodes a novel enzyme required for two very different ...
Bernhard T Hovemann+10 more
core +4 more sources
Histamine, histamine receptors, and neuropathic pain relief
Histamine, acting via distinct histamine H1, H2, H3, and H4 receptors, regulates various physiological and pathological processes, including pain. In the last two decades, there has been a particular increase in evidence to support the involvement of H3 ...
I. Obara+3 more
semanticscholar +1 more source
Histamine is a well-known inflammatory mediator, but how histamine induces angiogenesis remains poorly understood. In the present study, we demonstrated a dose-dependent dynamic tube formation in the human endothelial cell line EA.hy926 in the presence ...
Omer Faruk Hatipoglu+8 more
doaj
BACKGROUND & AIMS Histamine sensitizes the nociceptor transient reporter potential channel V1 (TRPV1) and has been shown to contribute to visceral hypersensitivity in animals.
M. Wouters+27 more
semanticscholar +1 more source
Graphical Abstract. Abstract Famotidine (FAM) is an efficacious competitive drug, and a reversible inhibitor of H2‐histaminergic receptor action used to manage acid production in the stomach. Among the elderly population, this drug poses the risk of kidney failure and impaired mental health conditions. Additionally, FAM is an environmental contaminant.
Pramod Ramachandra Vernekar+4 more
wiley +1 more source
IgE-Mediated Hypersensitivity Reactions to Cannabis in Laboratory Personnel [PDF]
Background: There have been sporadic reports of hypersensitivity reactions to plants of the Cannabinaceae family (hemp and hops), but it has remained unclear whether these reactions are immunologic or nonimmunologic in nature.
Anibarro B+17 more
core +1 more source