Results 161 to 170 of about 46,942 (270)

Use of Human In Vitro Gut Specimens for Translational Neurogastroenterology and Motility in the 21st Century

open access: yesNeurogastroenterology &Motility, EarlyView.
In vitro studies with GI surgical specimens or biopsy are a critical step in translating preclinical studies in animals to humans before testing potential therapeutic interventions in expensive clinical trials. Routine availability of human gut specimens, in combination with technological advances and powerful new in vitro models of the human ENS from ...
Dmitrii Pavlov, Fievos L. Christofi
wiley   +1 more source

COMPARISONS OF VARIOUS HISTAMINE ANTAGONISTS [PDF]

open access: yesBritish Journal of Pharmacology and Chemotherapy, 1948
openaire   +3 more sources

Impact of Opioid and Cannabis Use on Low‐Dose Amitriptyline Efficacy in Cyclical Vomiting Syndrome: A Real‐World Study in the United Kingdom

open access: yesNeurogastroenterology &Motility, Volume 37, Issue 6, June 2025.
This article presents the outcomes of a three‐tiered outpatient treatment algorithm for the prophylactic management of cyclical vomiting syndrome (CVS). Three key messages: (1) 61% of patients responded to the treatment algorithm, (2) opioid cessation was associated with clinical response to the treatment algorithm (p = 0.03), and (3) a low‐dose ...
Mohsin F. Butt   +4 more
wiley   +1 more source

HDC/histamine Signaling Axis Drives Macrophage Reprogramming to Promote Angiogenesis in Hindlimb-Ischemic Mice. [PDF]

open access: yesInt J Biol Sci
Sun D   +10 more
europepmc   +1 more source

Defective lymphatic vasculature in obesity

open access: yesObesity Reviews, EarlyView.
Summary Lymphedema is an important, and often underdiagnosed complication of obesity and is likely due to acquired defects in the lymphatic vasculature. Study of diet‐induced obesity animal models have indicated defective lymphatic vasculatures might extend to other anatomical sites, especially visceral depots.
Jingjing Zhu, John P. H. Wilding, Ji Hu
wiley   +1 more source

Oxyntomodulin physiology and its therapeutic development in obesity and associated complications

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Physiological influences of OXM and its emerging insights from evidence on bariatric surgery effects. CCK, cholecystokinin; FGF21, fibroblast growth factor 21; GLUT4, glucose transporter type 4; IRS1, insulin receptor substrate‐1; NNMT, nicotinamide N‐methyltransferase; OXM, oxyntomodulin Abstract Incretins, such as glucagon‐like
Martin T. W. Kueh   +3 more
wiley   +1 more source

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