Perioperative uses of histamine antagonists [PDF]
Journal of Clinical Anesthesia, 1990 bei pubmed Zusatz zum Titel: "Review. Erratum in: J Clin Anesth 1991 Mar-Apr;3(2):170"
Lorenz, Wilfried +3 more
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Multiple Targeting Approaches on Histamine H3 Receptor Antagonists [PDF]
Frontiers in Neuroscience, 2016 With the very recent market approval of pitolisant (Wakix®), the interest in clinical applications of novel multifunctional histamine H3 receptor antagonists has clearly increased. Since histamine H3 receptor antagonists in clinical development have been
Mohammad eKhanfar +5 more
doaj +3 more sources
Effects of histamine and its antagonists on murine T-cells and bone marrow-derived dendritic cells [PDF]
Drug Design, Development and Therapy, 2015 Xiufen Hu,1,* Mohammad Ishraq Zafar,2,* Feng Gao2 1Department of Paediatrics, Tongji Hospital, 2Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China *
Hu XF, Zafar MI, Gao F
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Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells
Scientific Reports, 2021 Cancer therapy is often hampered by the disease’s development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is ...
Nobuki Matsumoto +5 more
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Role of Substance P on Histamine H3 Antagonist-Induced Scratching Behavior in Mice
Journal of Pharmacological Sciences, 2006 .: The purpose of the present study was to investigate the involvement of chemical mediators, other than histamine, in the scratching behavior induced by H3 antagonists.
Maria Alejandra Hossen +5 more
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Are hypotension and rash after atracurium really caused by histamine release? [PDF]
, 1994 A prospective, randomized, double-blind study was performed in 40 patients (ASA class I-III) treated with atracurium to ascertain whether histamine release caused hemodynamic or cutaneous changes.
Doenicke, A. +4 more
core +1 more source
Perioperative nonspecific histamine release: a new classification by aetiological mechanisms and evaluation of their clinical relevance [PDF]
, 1993 As a consequence of the performance of a randomized controlled clinical trial on perioperative histamine release and cardiovascular and respiratory disturbances, several types of increases in plasma histamine had to be distinguished instead of only two ...
Lorenz, Wilfried +9 more
core +1 more source
Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials [PDF]
, 1982 To demonstrate the efficacy of a premedication with H1- + H2-receptor antagonists against histamine-release responses in anaesthesia and surgery 3 randomized controlled trials were conducted in patients, volunteers and experimental animals (dogs ...
Lorenz, Wilfried +5 more
core +1 more source
Investigations on neuropeptide Y and histamine receptors by fluorescence-based and radiochemical methods [PDF]
, 2011 In the last three decades, a large amount of experimental data (for example Förster resonance energy transfer (FRET) at fluorescently labelled receptors) supported the hypothesis of the dimerization of G-protein-coupled receptors (GPCR), including ...
Lopuch, Miroslaw
core +1 more source
Pharmaceuticals, 2021 Noting the worldwide rapid increase in the prevalence of overweight and obesity new effective drugs are now being sought to combat these diseases. Histamine H3 receptor antagonists may represent an effective therapy as they have been shown to modulate ...
Kamil Mika +12 more
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