Results 11 to 20 of about 167,267 (301)

Perioperative uses of histamine antagonists [PDF]

open access: yesJournal of Clinical Anesthesia, 1990
bei pubmed Zusatz zum Titel: "Review. Erratum in: J Clin Anesth 1991 Mar-Apr;3(2):170"
W, Lorenz   +3 more
openaire   +4 more sources

Multiple Targeting Approaches on Histamine H3 Receptor Antagonists [PDF]

open access: yesFrontiers in Neuroscience, 2016
With the very recent market approval of pitolisant (Wakix®), the interest in clinical applications of novel multifunctional histamine H3 receptor antagonists has clearly increased. Since histamine H3 receptor antagonists in clinical development have been
Mohammad eKhanfar   +5 more
doaj   +2 more sources

The dopaminergic system is able to modulate the central histamine-induced pressor effect in hemorrhage-shocked rats

open access: yesAnnales Academiae Medicae Silesiensis
Introduction: Histamine administered intracerebroventricularly (icv) induces a resuscitating effect in hemorrhage-shocked rats. Dopamine receptors are present in neuronal pathways involved in central cardiovascular regulation; therefore, the aim of the ...
Karolina Jasikowska   +5 more
doaj   +2 more sources

Effects of histamine and its antagonists on murine T-cells and bone marrow-derived dendritic cells

open access: yesDrug Design, Development and Therapy, 2015
Xiufen Hu,1,* Mohammad Ishraq Zafar,2,* Feng Gao2 1Department of Paediatrics, Tongji Hospital, 2Department of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, People’s Republic of China *
Hu XF, Zafar MI, Gao F
doaj   +1 more source

Pathophysiological Roles of Histamine Receptors in Cancer Progression: Implications and Perspectives as Potential Molecular Targets

open access: yesBiomolecules, 2021
High levels of histamine and histamine receptors (HRs), including H1R~H4R, are found in many different types of tumor cells and cells in the tumor microenvironment, suggesting their involvement in tumor progression.
Phuong Linh Nguyen, Jungsook Cho
doaj   +1 more source

Histamine H1 receptor antagonists selectively kill cisplatin-resistant human cancer cells

open access: yesScientific Reports, 2021
Cancer therapy is often hampered by the disease’s development of resistance to anticancer drugs. We previously showed that the autonomously upregulated product of fibroblast growth factor 13 gene (FGF13; also known as FGF homologous factor 2 (FHF2)) is ...
Nobuki Matsumoto   +5 more
doaj   +1 more source

Role of Substance P on Histamine H3 Antagonist-Induced Scratching Behavior in Mice

open access: yesJournal of Pharmacological Sciences, 2006
.: The purpose of the present study was to investigate the involvement of chemical mediators, other than histamine, in the scratching behavior induced by H3 antagonists.
Maria Alejandra Hossen   +5 more
doaj   +1 more source

Are hypotension and rash after atracurium really caused by histamine release? [PDF]

open access: yes, 1994
A prospective, randomized, double-blind study was performed in 40 patients (ASA class I-III) treated with atracurium to ascertain whether histamine release caused hemodynamic or cutaneous changes.
Doenicke, A.   +4 more
core   +1 more source

Perioperative nonspecific histamine release: a new classification by aetiological mechanisms and evaluation of their clinical relevance [PDF]

open access: yes, 1993
As a consequence of the performance of a randomized controlled clinical trial on perioperative histamine release and cardiovascular and respiratory disturbances, several types of increases in plasma histamine had to be distinguished instead of only two ...
Lorenz, Wilfried   +9 more
core   +1 more source

Prophylaxis of anaphylactoid reactions to a polypeptidal plasma substitute by H1- plus H2-receptor antagonists: synopsis of three randomized controlled trials [PDF]

open access: yes, 1982
To demonstrate the efficacy of a premedication with H1- + H2-receptor antagonists against histamine-release responses in anaesthesia and surgery 3 randomized controlled trials were conducted in patients, volunteers and experimental animals (dogs ...
Lorenz, Wilfried   +5 more
core   +1 more source

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