Results 121 to 130 of about 35,308 (311)

Blocking H1/H2 histamine receptors inhibits damage/fibrosis in Mdr2–/– mice and human cholangiocarcinoma tumorigenesis

Hepatology, 2018
Primary sclerosing cholangitis (PSC) patients are at risk of developing cholangiocarcinoma (CCA). We have shown that (1) histamine increases biliary hyperplasia through H1/H2 histamine receptors (HRs) and (2) histamine levels increase and mast cells (MCs)
Lindsey Kennedy, Laura A Hargrove, Jennifer Demieville, W. Karstens, Hannah Jones, S. DeMorrow, F. Meng, P. Invernizzi, F. Bernuzzi, G. Alpini, Steven A. Smith, Austin Akers, Vik Meadows, H. Francis   +13 more
semanticscholar   +1 more source

敗血症による臓器傷害進展におけるヒスタミンの寄与 [PDF]

, 2016
富山大学・富医薬博高210号・服部瑞樹・2016/6 ...
服部 瑞樹
core   +1 more source

Monoaminergic Neuropathology in Alzheimer's disease [PDF]

, 2017
Acknowledgments This work was supported by The Croatian Science Foundation grant. no. IP-2014-09-9730 (“Tau protein hyperphosphorylation, aggregation, and trans-synaptic transfer in Alzheimer’s disease: cerebrospinal fluid analysis and assessment of ...
Bažadona, Danira, Buée, Luc, Delalle, Ivana, Giovanni, Giuseppe Di, Harrington, Charles R., Hof, Patrick R., Jovanov-Milošević, Nataša, Leko, Mirjana Babić, Silva, Rohan de, Wischik, Claude M., Wray, Selina, Šimić, Goran   +11 more
core   +1 more source

Histamine H4 receptor regulates IL-6 and INF-γ secretion in native monocytes from healthy subjects and patients with allergic rhinitis

Clinical and Translational Allergy, 2019
Histamine H1 receptor (H1R) and histamine H4 receptor (H4R) are essential in allergic inflammation. The roles of H4R have been characterized in T cell subsets, whereas the functional properties of H4R in monocytes remain unclear.
Hua Peng, Jian Wang, Xiao Yan Ye, Jie Cheng, Cheng Zhi Huang, Li Yue Li, Tian Ying Li, Chun Wei Li   +7 more
doaj   +1 more source

The Use of H1 and H2 Histamine Antagonists with Morphine Anesthesia [PDF]

, 1981
Daniel M. Philbin, Jonathan Moss, Cary W. Akins, Carl E. Rosow, Katsuakira Kono, Robert Schneider, Thomas R. Verlee, John J. Savarese   +7 more
openalex   +1 more source

Screening and identification of the H1R antagonists from natural products by BODIPY FL histamine recognition and DPHD-anchored bombardment coupled with target cell extraction

Frontiers in Pharmacology
IntroductionHistamine is an important mediator of allergy, and inhibiting its binding to H1 receptors (H1R) is a key method to alleviate allergic diseases.
Xinqi Li, Guizhou Hu, Guizhou Hu, Xu Chen, Can Di, Jin Qi   +5 more
doaj   +1 more source

Activation of Microglia by Histamine and Substance P

Cellular Physiology and Biochemistry, 2014
Background: Activated microglia perform many of the immune effector functions typically associated with macrophages. However, the regulators involved in microglial activation are not well defined.
Jin Zhu, Chen Qu, Xiang Lu, Shu Zhang
doaj   +1 more source

Cardioactive effects of diphenhydramine and curcumin in Daphnia magna [PDF]

, 2009
Although used as a model for examining the cardioactive effects of various compounds, the neuromuscular regulation of the heart of the crustacean Daphnia magna (D. magna) is not well understood.
Avinash Vaidya, Laura Gurenlian, Lauren Brady, Noelle Erin Romero, Rebecca Kohn   +4 more
core  

Involvement of histamine H1 and H2 receptor inverse agonists in receptor's crossregulation [PDF]

, 2019
Histamine [2-(4-Imidazolyl)-ethylamine] modulates different biological processes, through histamine H1 and H2 receptors, and their respective blockers are widely used in treating allergic and gastric acid-related disorders.
Burghi, Valeria, Davio, Carlos Alberto, Díaz, Antonela Susana, Fernandez, Natalia Cristina, Monczor, Federico, Rodriguez Gonzalez, Angela Paola, Sahores, Ana, Shayo, Carina Claudia, Sosa, Máximo Hernán, Zappia, Carlos Daniel   +9 more
core   +1 more source

Terfenadine, a potent histamine H1‐receptor antagonist in the treatment of grass pollen sensitive asthma. [PDF]

, 1990
P Rafferty, Linda Jackson, Roger M. Smith, ST Holgate   +3 more
openalex   +1 more source