Results 81 to 90 of about 267,254 (237)

Histamine and migraine revisited: mechanisms and possible drug targets

The Journal of Headache and Pain, 2019
Objective To review the existing literature on histamine and migraine with a focus on the molecule, its receptors, its use in inducing migraine, and antihistamines in the treatment of migraine. Background Histamine has been known to cause a vascular type
Jacob Worm, Katrine Falkenberg, Jes Olesen   +2 more
doaj   +1 more source

Role of Neuroinflammation in Autism Spectrum Disorder and the Emergence of Brain Histaminergic System. Lessons Also for BPSD?

Frontiers in Pharmacology, 2020
Many behavioral and psychological symptoms of dementia (BPSD) share similarities in executive functioning and communication deficits with those described in several neuropsychiatric disorders, including Alzheimer’s disease (AD), epilepsy, schizophrenia ...
Nermin Eissa, Nermin Eissa, Adel Sadeq, Astrid Sasse, Bassem Sadek, Bassem Sadek   +5 more
doaj   +1 more source

Rebound Pruritus and Urticaria After Discontinuation of Chronic Antihistamine Use—A Scoping Review

Clinical &Experimental Allergy, EarlyView.
Rebound pruritus and urticaria have been reported after discontinuation of chronic cetirizine or levocetirizine use only. Symptoms typically occur within 0.5–5 days after stopping therapy and appear more frequently reported in female patients. Re‐initiation of antihistamines is the most commonly effective management strategy, highlighting the need for ...
Jun Jie Benjamin Seng, Prawira Oka, Ngiap Chuan Tan   +2 more
wiley   +1 more source

A comparative study of in vitro contractility between gut tissues of Hirschsprung’s disease and other gut malformations

National Journal of Physiology, Pharmacy and Pharmacology, 2017
Background: Hirschsprung’s disease and other gut malformations commonly present with obstructive features of gut in pediatric age group. Problem of obstruction persists even after resection and anastomosis operation.
Anil Kumar Tiwari, Sanjeev K. Singh, Ratna Pandey, Phani Bhushan Singh, Shashikant C.U. Patne, Ajay N. Gangopadhyay, Maloy B Mandal   +6 more
doaj   +1 more source

Histamine release and fibrinogen adsorption mediate acute inflammatory responses to biomaterial implants in humans

Journal of Translational Medicine, 2007
Background Medical implants often fail as a result of so-called foreign body reactions during which inflammatory cells are recruited to implant surfaces.
Eaton John W, Zdolsek Johann, Tang Liping   +2 more
doaj   +1 more source

Swiss Practice Recommendations for Chronic Prurigo Including Prurigo Nodularis

International Journal of Dermatology, EarlyView.
Chronic prurigo, including prurigo nodularis, is a chronic, often treatment‐refractory condition characterized by persistent pruritus and chronic scratch lesions. Advances in the understanding of its underlying pathophysiology have enabled the development of novel targeted therapies; however, management remains challenging due to the expanding range of
Simon M. Mueller, Helmut Beltraminelli, Wolf‐Henning Boehncke, Maximilian Böhm, Antonio Cozzio, Peter Häusermann, Ahmad Jalili, Antonios G. A. Kolios, Claudia Lang, Eva Loos, Christoph Schlapbach, Curdin Conrad   +11 more
wiley   +1 more source

Effects of administration of histamine and its H1, H2, and H3 receptor antagonists into the primary somatosensory cortex on inflammatory pain in rats [PDF]

Iranian Journal of Basic Medical Sciences, 2014
Objective(s): The present study investigated the effects of microinjection of histamine and histamine H1, H2, and H3 receptor antagonists, chlorpheniramine, ranitidine and thioperamide, respectively into the primary somatosensory cortex (PSC) on ...
Esmaeal Tamaddonfard, Nasrin Hamzeh Gooshchi   +1 more
doaj  

Histamine H1 receptor antagonists enhance the efficacy of antibacterials against Escherichia coli

BMC Veterinary Research, 2019
Background H1 receptor antagonists are commonly used for the treatment of allergic diseases. The aim of this study was to find out, if antihistaminic compounds like mepyramine have the ability to influence the activity of antibacterials.
G. G. Bruer, P. Hagedorn, M. Kietzmann, A. F. Tohamy, V. Filor, E. Schultz, S. Mielke-Kuschow, J. Meissner   +7 more
doaj   +1 more source

Pathophysiology and emerging treatments for dermographic, cholinergic and cold urticaria

Journal of the European Academy of Dermatology and Venereology, EarlyView.
This review illustrates key proposed mast cell‐mediated activation pathways in dermographic, cholinergic and cold urticaria, highlighting IgE‐dependent and ‐independent mechanisms. These pathways are increasingly targeted by emerging drugs, aiming to interrupt mast cell activation and mediator release, offering more precise, mechanism‐based treatment ...
Mojca Bizjak‐Suran, Matjaž Fležar, Manuel Pedro Pereira   +2 more
wiley   +1 more source

Efeito hiponociceptivo da histamina intra-articular [PDF]

, 2012
Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro de Ciências Biológicas, Programa de Pós-Graduação em Farmacologia, Florianópolis, 2009.Histamina é encontrada no líquido sinovial de pacientes indivíduos saudáveis e em diversos ...
Silva, Eduardo Souza
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