Results 1 to 10 of about 164 (159)

Biosynthesis of Histidine [PDF]

open access: yesEcoSal Plus, 2009
The biosynthesis of histidine in Escherichia coli and Salmonella typhimurium has been an important model system for the study of relationships between the flow of intermediates through a biosynthetic pathway and the control of the genes encoding the enzymes that catalyze the steps in a ...
Malcolm E. Winkler   +1 more
openaire   +3 more sources

[Roles of Histidine Kinases and Histidine Phosphatases in Cancer].

open access: yesZhongguo fei ai za zhi = Chinese journal of lung cancer, 2021
Phosphorylation is the most common and important post-translational modification of proteins, which plays an important role in the regulation of cell proliferation, differentiation, development and metabolism, and is closely related to the tumorigenesis and metastasis of cancer.
Lili Guo   +3 more
openaire   +4 more sources

Carboplatin binding to histidine [PDF]

open access: yesActa Crystallographica Section F Structural Biology Communications, 2014
Carboplatin is a second-generation platinum anticancer agent used for the treatment of a variety of cancers. Previous X-ray crystallographic studies of carboplatin binding to histidine (in hen egg-white lysozyme; HEWL) showed the partial conversion of carboplatin to cisplatin owing to the high NaCl concentration used in the crystallization conditions ...
Tanley, Simon W. M.   +5 more
openaire   +7 more sources

Tautomerism in Neutral Histidine

open access: yesAngewandte Chemie International Edition, 2014
AbstractHistidine is an important natural amino acid, involved in many relevant biological processes, which, because of its physical properties, proved difficult to characterize experimentally in its neutral form. In this work, neutral histidine has been generated in the gas phase by laser ablation of solid samples and its NεH tautomeric form unraveled
Bermúdez, Celina   +3 more
openaire   +4 more sources

Histidine Metabolism and Function [PDF]

open access: yesThe Journal of Nutrition, 2020
Histidine is a dietary essential amino acid because it cannot be synthesized in humans. The WHO/FAO requirement for adults for histidine is 10 mg · kg body weight-1 · d-1. Histidine is required for synthesis of proteins. It plays particularly important roles in the active site of enzymes, such as serine proteases (e.g., trypsin) where it is a member of
Margaret E. Brosnan, John T. Brosnan
openaire   +3 more sources

Histidine Biosynthesis [PDF]

open access: yesThe Arabidopsis Book, 2011
Histidine (His) is one of the standard amino acids in proteins, and plays a critical role in plant growth and development. The chemical properties of the imidazole side group allow His to participate in acid-base catalysis, and in the co-ordination of metal ions.
openaire   +2 more sources

HISTIDINE BIOTRANSFORMATION MEDIATED BY L-HISTIDINE-AMMONIA-LYASE

open access: yesFoods and Raw Materials, 2013
Kinetics of the metabolism of the heterocyclic amino acid histidine exposed to the L-histidine ammonia-lyase enzyme has been investigated and the technology of extraction of histidine biotransformation products (urocanic acid and ammonia) from casein hydrolyzates enabling the subsequent use of these hydrolyzates as a milk protein concentrate for the ...
Borisova, G., Bessonova, O.
openaire   +4 more sources

Fluorometric Determination of Histidine

open access: yesClinical Chemistry, 1969
Abstract An accurate and precise fluorometric procedure was developed for the determination of histidine based on the observation that o-phthalaldehyde forms a fluorophor with the analogous compound, histamine. The precision of the method was improved, and the fluorophor was stabilized for days by the addition of a phosphoric acid ...
Joe Burton   +4 more
openaire   +3 more sources

Compartmentation in histidine biosynthesis [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 1972
Abstract 1. 1. Biochemical compartmentation, in the sense of intermediates in a pathway not being freely miscible with other cellular pools of the same compounds, was investigated in histidine biosynthesis in Salmonella typhimurium and Saccharomyces cerevisiae . 2. 2. The experimental approach involved measurement of the degree of dilution
Lydia Bearden, V. Moses
openaire   +2 more sources

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