Results 1 to 10 of about 228,380 (298)

Knocking out histidine ammonia-lyase by using CRISPR-Cas9 abolishes histidine role in the bioenergetics and the life cycle of Trypanosoma cruzi [PDF]

open access: yesMicrobial Cell
Trypanosoma cruzi, the causing agent of Chagas disease, is the only known trypanosomatid pathogenic to humans having a complete histidine to glutamate pathway, which involves a series of four enzymatic reactions that convert histidine into downstream ...
Janaína de Freitas Nascimento   +7 more
doaj   +2 more sources

Is Deuterium Sequestering by Reactive Carbon Atoms an Important Mechanism to Reduce Deuterium Content in Biological Water? [PDF]

open access: yesFASEB BioAdvances
Deuterium is a natural heavy isotope of hydrogen, having a neutron as well as a proton. Deuterium disrupts ATP synthesis in mitochondria, causing increased production of reactive oxygen species and reduced synthesis of ATP.
Stephanie Seneff   +2 more
doaj   +2 more sources

Fluorometric Determination of Histidine

open access: bronzeClinical Chemistry, 1969
Abstract An accurate and precise fluorometric procedure was developed for the determination of histidine based on the observation that o-phthalaldehyde forms a fluorophor with the analogous compound, histamine. The precision of the method was improved, and the fluorophor was stabilized for days by the addition of a phosphoric acid ...
John A. Ambrose   +4 more
openalex   +4 more sources

Histidine Alleviates Impairments Induced by Chronic Cerebral Hypoperfusion in Mice

open access: yesFrontiers in Physiology, 2018
Chronic cerebral hypoperfusion is one of the fundamental pathological causes of brain disease such as vascular dementia. Exploration of effective treatments for this is of great interest.
You Wan, Huailian Guo
exaly   +3 more sources

The incorporation of Me-histidine complexes in the structure of FAU-type zeolite: Characterization of the obtained materials [PDF]

open access: yesHemijska Industrija, 2008
L-histidine, a naturally occurring amino acid, was incorporated inside the supercages of FAU type zeolite in a form of Me-complex entity (Me = Cu(II), Zn(II), Fe(III)).
Stošić Dušan   +5 more
doaj   +1 more source

Synthesis and Assessment of Antiplatelet and Antithrombotic Activity of 4-Amino-Substituted 5-Oxoproline Amides and Peptides

open access: yesMolecules, 2023
Venous thromboembolism is a serious problem because it significantly increases the risk of developing vascular complications in elderly patients with obesity or immobilization, cancer, and many other diseases.
Victor P. Krasnov   +10 more
doaj   +1 more source

Electrochemical Shell-Isolated Nanoparticle-Enhanced Raman Spectroscopy of Imidazole Ring Functionalized Monolayer on Smooth Gold Electrode

open access: yesMolecules, 2022
The imidazole ring (Im) of histidine side chains plays a unique role in the function of proteins through covalent bonding with metal ions and hydrogen bonding interactions with adjusted biomolecules and water. At biological interfaces, these interactions
Agnė Zdaniauskienė   +5 more
doaj   +1 more source

pH Dependence on Colorimetric Detection of Hg2+ by Histidine-Functionalized Gold Nanoparticles

open access: yesIndonesian Journal of Chemistry, 2020
In this study, we successfully developed gold nanoparticles capped with histidine (His-AuNPs) for Hg2+ detection using trisodium citrate as the reducing agent. The optimum pH for the detection of Hg2+ by His-AuNPs was 12.
Dewi Eviane   +2 more
doaj   +1 more source

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