Results 31 to 40 of about 435,238 (305)
Ligand entry in human ileal bile acid-binding protein is mediated by histidine protonation [PDF]
, 2019 Human ileal bile acid-binding protein (hI-BABP) has a key role in the intracellular transport of bile salts. To explore the role of histidine protonation in the binding process, the pH-dependence of bile salt binding and internal dynamics in hI-BABP was ...
Egyed, Orsolya +6 more
core +4 more sources
Biomimetics, 2019 Biology offers a valuable inspiration toward the development of self-healing engineering composites and polymers. In particular, chemical level design principles extracted from proteinaceous biopolymers, especially the mussel byssus, provide inspiration ...
Stefan Zechel +3 more
doaj +1 more source
Identity and function of an essential nitrogen ligand of the nitrogenase cofactor biosynthesis protein NifB. [PDF]
, 2020 NifB is a radical S-adenosyl-L-methionine (SAM) enzyme that is essential for nitrogenase cofactor assembly. Previously, a nitrogen ligand was shown to be involved in coupling a pair of [Fe4S4] clusters (designated K1 and K2) concomitant with carbide ...
Britt, R David +7 more
core +1 more source
Chemosensors, 2023 Histidine is an essential amino acid with significant implications for human growth and neuromodulation. Its intracellular concentration, whether increased or decreased, can indicate different diseases.
Xinyi Li, Zezhou Li, Meiping Zhao
doaj +1 more source
Antioxidants, 2023 Metal chelators are used for various industrial and medical purposes based on their physicochemical properties and biological activities. In biological systems, copper ions bind to certain enzymes as cofactors to confer catalytic activity or bind to ...
Jae Won Ha +2 more
doaj +1 more source
The identification of histidine ligands to cytochrome a in cytochrome c oxidase [PDF]
, 1985 A histidine auxotroph of Saccharomyces cerevisiae has been used to metabolically incorporate [1,3-15N2] histidine into yeast cytochrome c oxidase. Electron nuclear double resonance (ENDOR) spectroscopy of cytochrome a in the [15N]histidine-substituted ...
Chan, Sunney I. +2 more
core
Proton transfer in histidine-tryptophan heterodimers embedded in helium droplets
, 2015 We used cold helium droplets as nano-scale reactors to form and ionize, by electron bombardment and charge transfer, aromatic amino acid heterodimers of histidine with tryptophan, methyl-tryptophan, and indole. The molecular interaction occurring through
Bellina, Bruno +2 more
core +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Structural Effects on the Reaction of Singlet Oxygen with Tertiary Amines in Aqueous Solution
OxygenPhotosensitized excitation of molecular oxygen generates singlet oxygen, a reactive oxygen species that has been studied in biological systems, synthetic methods and in aquatic ecosystems.
Grace Sliwinski +2 more
doaj +1 more source
The Saudi Journal of Gastroenterology, 2017 Background/Aim: We investigated the association between blood amino acid concentration changes caused by elemental diet (ED) and their relationship to its therapeutic effect. Patients and Methods: Patients with active Crohn's disease (CD) followed ED for
Masakazu Nakano +5 more
doaj +1 more source