Results 131 to 140 of about 228,380 (298)

Advancements in DNA‐Driven Precision Modulation of Cell Surface Receptor for Programmable Cellular Functions

open access: yesAdvanced Science, EarlyView.
DNA‐Based Genetic and Non‐Genetic Tools for Receptor Engineering. This review highlights recent advances in DNA‐based strategies for receptor engineering, including genetic approaches like domain fusion and site‐directed mutagenesis, as well as non‐genetic methods using functional nucleic acids, DNA nanostructures, and dynamic DNA reactions.
Hexin Nan   +4 more
wiley   +1 more source

Estimation of the leucine and histidine requirements for piglets fed a low-protein diet

open access: yesAnimal, 2016
Reduction of the CP content in the diets of piglets requires supplementation with crystalline essential amino acids (AA). Data on the leucine (Leu) and histidine (His) requirements of young pigs fed low-CP diets are limited and have primarily been ...
A.G. Wessels   +5 more
doaj  

THE RELATION OF ARGININE AND HISTIDINE TO GROWTH

open access: hybrid, 1924
William C. Rose, Gerald J. Cox
openalex   +1 more source

Phenylalanine‐Based DNA‐Encoded Chemical Libraries for the Discovery of Potent and Selective Small Organic Ligands Against Markers of Cancer and Immune Cells

open access: yesAdvanced Science, EarlyView.
FM‐DEL1 and FM‐DEL2 are constructed by installing one or two sets of building blocks on a phenylalanine central scaffold. FM‐DELs are screened against markers of prostate, and renal cell carcinoma, and against an immunological target expressed on the surface of natural killer cells.
Francesca Migliorini   +12 more
wiley   +1 more source

Quorum Sensing Inhibits Type III‐A CRISPR‐Cas System Activity Through Repressing Positive Regulators SarA and ArcR in Staphylococcus Aureus

open access: yesAdvanced Science, EarlyView.
This study proposes a novel model illustrating how quorum sensing (QS) regulates the type III‐A CRISPR‐Cas system in Staphylococcus aureus. The QS regulator AgrA suppresses CRISPR‐Cas activity by downregulating the transcriptional regulators SarA and ArcR.
Yang Li   +6 more
wiley   +1 more source

Safety and efficacy of the feed additives l-histidine and l-histidine monohydrochloride monohydrate produced with <i>Corynebacterium glutamicum</i> KCCM 80389 for all animal species (CJ Europe GmbH). [PDF]

open access: yesEFSA J
EFSA Panel on Additives and Products or Substances used in Animal Feed (FEEDAP)   +21 more
europepmc   +1 more source

Engineering Decavalent, Sperm‐Binding Laminin‐IgG Hybrid Antibodies for Potent Non‐Hormonal Contraception

open access: yesAdvanced Science, EarlyView.
This study investigates a highly multivalent mAb platform fusing Laminin‐511 heterotrimerization domains with Fabs and IgG1‐Fc as a non‐hormonal contraceptive. The most potent molecule ‘LamH10’, possessing 10 Fabs, rapidly achieved >99% reduction in progressively motile sperm at just 33µg per dose in sheep, making the laminin‐IgG hybrid platform the ...
Alison Schaefer   +8 more
wiley   +1 more source

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