Results 21 to 30 of about 164 (159)

Strategies to Design and Optimize Artificial Antigen‐Presenting Cells for T Cell Expansion in Cancer Immunotherapy

open access: yesAdvanced Functional Materials, EarlyView.
This review highlights recent advances in engineering artificial antigen‐presenting cells (aAPCs) as alternatives to dendritic cells for T cell expansion. Key design principles inspired by the immunological synapse are discussed, with emphasis on strategies for polyclonal and antigen‐specific T cell expansion.
Nguyen Thi Nguyen, Yu Seok Youn
wiley   +1 more source

Advanced Multipurpose Spectroscopic Nanobio‐Device for Concurrent Lab‐on‐a‐Chip Label‐Free Separation and Detection of Extracellular Vesicles as Key‐Biomarkers for Point‐of‐Care Cardiovascular Disease Diagnostics

open access: yesAdvanced Healthcare Materials, EarlyView.
AIMSPec‐LoC is a novel lab‐on‐a‐chip platform integrating size‐based extracellular vesicle (EVs) separation with label‐free Raman spectroscopy and AI‐powered classification via SKiNET. This high‐throughput, portable system enables real‐time, multiplexed molecular fingerprinting of EVs from biofluids, offering transformative potential for early, non ...
Emma Buchan   +3 more
wiley   +1 more source

Designing for Degradation: Transient Devices Enabled by (Nano)Cellulose

open access: yesAdvanced Materials, EarlyView.
Recent progress in transient devices enabled by (nano)cellulosic materials is reviewed. Transiency mechanisms, advantages of nanocelluloses, and a suite of applications are discussed. A circular thinking approach coupled with life cycle assessment is applied to critically revisit the potential, advantages, and challenges of nanocellulose‐enabled ...
Lucas J. Andrew   +2 more
wiley   +1 more source

Functional Biomaterials Derived from Protein Liquid–Liquid Phase Separation and Liquid‐to‐Solid Transition

open access: yesAdvanced Materials, EarlyView.
Protein can undergo liquid–liquid phase separation and liquid‐to‐solid transition to form liquid condensates and solid aggregates. These phase transitions can be influenced by post‐translational modifications, mutations, and various environmental factors.
Tianchen Li   +3 more
wiley   +1 more source

Structured Light Projection Using Image Guide Fibers for In Situ Photo‐biofabrication

open access: yesAdvanced Materials, EarlyView.
Light‐based biofabrication is typically performed with single wavelength light sources and within benchtop devices. This work demonstrates FaSt‐Light (Fiber‐assisted Structured Light) as a new approach to achieve multiwavelength image projection using flexible image guide fibers, which enables a variety of applications for in situ biofabrication ...
Parth Chansoria   +8 more
wiley   +1 more source

Polyanhydride‐Based Microparticles for Programmable Pulsatile Release of Diphtheria Toxoid (DT) for Single‐Injection Self‐Boosting Vaccines

open access: yesAdvanced Materials, EarlyView.
This study presents a polyanhydride‐based delivery platform for single‐injection, self‐boosting vaccines. The system enables programmable, pulsatile release of diphtheria toxoid with high antigen recovery and is guided by machine learning for tunability. In vivo results show immune responses comparable to multi‐dose regimens, highlighting its potential
Linzixuan Zhang   +17 more
wiley   +1 more source

Ueber das Histidin. [PDF]

open access: yesHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1899
n ...
Kossel, A., Kutscher, Fr.
openaire   +2 more sources

Mussel‐Inspired Molecular Strategies for Fabricating Functional Materials With Underwater Adhesion and Self‐Healing Properties

open access: yesAdvanced Materials, EarlyView.
This review systematically examines the nanomechanical mechanisms of mussel‐inspired molecular interactions, primarily investigated by direct force measurement techniques such as surface forces apparatus and atomic force microscopy. The macroscopic adhesive and self‐healing performances of mussel‐inspired functional materials, including coacervates ...
Pan Huang, Hongjian Zhang, Hongbo Zeng
wiley   +1 more source

Histidine Biosynthesis

open access: yes, 1980
Publisher Summary This chapter focuses on histidine biosynthesis. Histidine derives its carbon and nitrogen from ATP, ribose, and glutamine. The first product of the pathway of histidine biosynthesis, 5-phosphoribyosyl-1-pyrophosphate (PRPP), is also the starting point for the synthesis of purine nucleotides and a substrate for the synthesis of ...
openaire   +2 more sources

New Efficient D‐π‐A and A‐π‐A Structured Type I Radical Photoinitiators for Additive Manufacturing Nanomaterials Preparation

open access: yesAdvanced Materials Technologies, EarlyView.
Groundbreaking advancements are discovered in 3D printing with new type‐I radical photoinitiators, including 1,1‐dimethoxy‐1‐phenylpropan‐2‐one. These innovative compounds, effective under visible light, enhance photopolymerization of acrylates and methacrylates, facilitating the creation of efficient nanocomposites and unlock the future of polymer ...
Andrzej Świeży   +5 more
wiley   +1 more source

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