Results 81 to 90 of about 186,471 (141)
Ionization behavior of the histidine residue in the catalytic triad of serine proteases [PDF]
, 1973 α-Lytic protease is a homologue of the mammalian serine proteases such as trypsin, chymotrypsin, and elastase, and its single histidine residue belongs to the Asp-His-Ser catalytic triad. This single histidine residue has been selectively enriched in the
Hunkapiller, Michael W. +3 more
core
Microbial CellTrypanosoma cruzi, the causing agent of Chagas disease, is the only known trypanosomatid pathogenic to humans having a complete histidine to glutamate pathway, which involves a series of four enzymatic reactions that convert histidine into downstream ...
Janaína de Freitas Nascimento +7 more
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Differences between β-Ala and Gly-Gly in the design of amino acids-based hydrogels
Beilstein Journal of Organic Chemistry, 2010 Despite the continuous interest in organogels and hydrogels of low molecular weight gelators (LMWG), establishing the relationship between the molecular structure and the gelation mechanism is still a challenge.
Andreea Pasc +3 more
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pKa Determination of a Histidine Residue in a Short Peptide Using Raman Spectroscopy
Molecules, 2019 Determining the pKa of key functional groups is critical to understanding the pH-dependent behavior of biological proteins and peptide-based biomaterials.
Brett H. Pogostin +3 more
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The spatial orientation of histidine via five-armed alkylamino siloxane improved the properties of the cationic gene delivery vector [PDF]
Biofunctional MaterialsThe efficiency of gene transfection using cationic polymers primarily depends on factors such as compact polyplex formation, cellular uptake, endosomal escape, cytoplasmic transport, nuclear entry, and the dissociation and release of plasmid from the ...
Viola B. Morris, Chandra P. Sharma
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International Journal of Electrochemical Science, 2016 Uniform sized copper nanospheres (CuNSs) were deposited at functionalised multiwalled carbon nanotubes (f-MWCNTs) modified glassy carbon electrode (GCE) through a simple electrochemical method.
Shen-Ming Chen +3 more
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Block of Kcnk3 by protons. Evidence that 2-P-domain potassium channel subunits function as homodimers. [PDF]
, 2001 KCNK subunits have two pore-forming P domains and four predicted transmembrane segments. To assess the number of subunits in each pore, we studied external proton block of Kcnk3, a subunit prominent in rodent heart and brain.
Goldstein, SA, Lopes, CM, Zilberberg, N
core
Beilstein Journal of Organic Chemistry, 2015 The success of siRNA-based therapeutics highly depends on a safe and efficient delivery of siRNA into the cytosol. In this study, we post-modified the primary amines on dendritic polyglycerolamine (dPG-NH2) with different ratios of two relevant amino ...
Fatemeh Sheikhi Mehrabadi +5 more
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Divalent Metal Binding Properties of the Methionyl Aminopeptidase from \u3cem\u3eEscherichia coli\u3c/em\u3e [PDF]
, 2000 The metal-binding properties of the methionyl aminopeptidase from Escherichia coli (MetAP) were investigated. Measurements of catalytic activity as a function of added Co(II) and Fe(II) revealed that maximal enzymatic activity is observed after the ...
Bennett, Brian +3 more
core +1 more source
Disruption of histidine and energy homeostasis in chronic obstructive pulmonary disease
International Journal of COPD, 2019 Wenqi Diao1, Wassim W Labaki2, MeiLan K Han2, Larisa Yeomans3, Yihan Sun4, Zyad Smiley4, Jae Hyun Kim3, Cora McHugh4, Pingchao Xiang5, Ning Shen6, Xiaoyan Sun6, Chenxia Guo6, Ming Lu6, Theodore J Standiford2, Bei He*,7, Kathleen A Stringer*,2,4 ...
Diao W +15 more
doaj