Results 81 to 90 of about 164 (159)
The Computer‐Assisted Sequence Annotation (CASA) workflow for enzyme discovery
Applications in Plant Sciences, EarlyView.Abstract Premise With the advent of inexpensive nucleic acid sequencing and automated annotation at the level of basic functionality, the central problem of enzyme discovery is no longer finding active sequences, it is determining which ones are suitable for further study.
Gemma R. Takahashi +3 more
wiley +1 more source
Animal Research and One Health, EarlyView.The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao +12 more
wiley +1 more source
Animal Research and One Health, EarlyView.Dietary supplement of sodium butyrate, may relate to regulating intestinal health and thus the growth performance and meat quality of rabbits by regulating the continuous process of promoting the periodic cycle of cecal epithelial cells. Abstract Supplementation of sodium butyrate (SB) has been proved to be beneficial for improving the growth ...
Mengke Ni +8 more
wiley +1 more source
Metal‐Mediated Protein Engineering within Live Cells
Chemistry – An Asian Journal, Volume 20, Issue 6, March 17, 2025.This review discusses how metal ions can mediate protein modification within live cells. With its easy handling, rapid solubility, and ease of internalization within the cells, metal ions can be an excellent stimulus for many organic reactions needed within an intracellular medium, which can modify proteins and lead to applications in chemistry ...
Pritam Ghosh
wiley +1 more source
Tuning Reactivity in Cu/TEMPO Catalyzed Alcohol Oxidation Reactions
Chemistry – An Asian Journal, EarlyView.Novel copper(I) complexes bearing a secondary amine moiety (CuL3) or an additional non‐innocent functionality with intact imine group (Cu2L42) were synthesized and tested towards oxidation reactions. Several intermediates, such as Cu(III)2(bis‐μ‐oxo) and Cu(II)2(bis‐μ‐hydroxo), species were trapped and spectroscopically characterized.
Maximilian Schütze +7 more
wiley +1 more source
Flux Sampling Suggests Metabolic Signatures of High Antibody‐Producing CHO Cells
Biotechnology and Bioengineering, EarlyView.ABSTRACT Chinese hamster ovary (CHO) cells remain the industry standard for producing numerous therapeutic proteins, particularly monoclonal antibodies (mAbs). However, achieving higher recombinant protein titers remains an ongoing challenge and a fundamental understanding of the cellular mechanism driving improved bioprocess performance remains ...
Kate E. Meeson +9 more
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.Biotransformation pathway from polyunsaturated fatty acids into dihydroxy fatty acids as lipid mediators by Escherichia coli expressing Chlamydomonas incerta 15S‐lipoxygenase with double oxygenating activity. The 15S‐lipoxygenase was the most efficient for the simultaneous production of resolvin D5 (7S,17S‐dihydroxydocosahexaenoic acid, 7S,17S‐DiHDHA ...
Hyun‐Ah Park, Jin Lee, Deok‐Kun Oh
wiley +1 more source
Biotechnology and Bioengineering, EarlyView.ABSTRACT Komagataella phaffii, also known as Pichia pastoris, is a powerful host for recombinant protein production, in part due to its exceptionally strong and tightly controlled PAOX1 promoter. Most K. phaffii bioprocesses for recombinant protein production rely on PAOX1 to achieve dynamic control in two‐phase processes.
Shannon M. Hoffman +4 more
wiley +1 more source