Results 91 to 100 of about 82,686 (281)

The MetaboHealth Score Enhances Insulin Resistance Metabotyping for Targeted Fat Loss: The PERSON Study

open access: yesObesity, EarlyView.
ABSTRACT Objective We previously identified distinct muscle and liver insulin resistance (IR) metabotypes in middle‐aged and older adults. The PERSON study showed that a low‐fat, high‐protein, high‐fiber diet benefits the muscle IR group, while a high‐monounsaturated fatty acid diet benefits the liver IR group. We also developed the MetaboHealth score,
Jordi Morwani‐Mangnani   +10 more
wiley   +1 more source

Smart Biomaterials and Dressings for the Treatment of Chronic Inflammatory Skin Diseases

open access: yesRare Metals, EarlyView.
ABSTRACT Chronic inflammatory skin diseases, encompassing immune‐inflammatory conditions and infection‐associated dermatoses, pose significant clinical challenges due to high prevalence, recurrence, and therapeutic resistance, affect over 30% of the global population.
Zehao Lan   +5 more
wiley   +1 more source

Segmental helical motions and dynamical asymmetry modulate histidine kinase autophosphorylation.

open access: yesPLoS Biology, 2014
Histidine kinases (HKs) are dimeric receptors that participate in most adaptive responses to environmental changes in prokaryotes. Although it is well established that stimulus perception triggers autophosphorylation in many HKs, little is known on how ...
Ariel E Mechaly   +3 more
doaj   +1 more source

Synthetic biology approaches to generate temperature‐sensitive alleles for the Sterile Insect Technique

open access: yesInsect Science, EarlyView.
Abstract The Sterile Insect Technique (SIT) is an environmentally friendly, sustainable pest control approach, which uses large‐scale releases of sterile insects to suppress or eradicate target populations through infertile matings. The efficiency of SIT is enhanced by male‐only releases requiring genetic sexing strains (GSSs) that are classically ...
Chun Yin Leung   +2 more
wiley   +1 more source

Extraocular Photoreception in Optic Lobes, Suckers, and Skin of Octopus vulgaris

open access: yesIntegrative Zoology, EarlyView.
Evidence of extra‐ocular photoreception in Octopus vulgaris (a) Diagram of the O. vulgaris different tissues considered: SPB, sucker proximal big; SPL, sucker proximal large; SM, sucker medium; SD, sucker distal; SK, skin; OL, optic lobes; RT, retina; (b‐d) Gene expression analysis of Ov‐GRK1 (red), Ov‐retinochrome (green), Ov‐rhodopsin (blue) mRNA ...
Valeria Maselli   +7 more
wiley   +1 more source

Vasoreactivity as a Measure of Kidney Viability During Ex Vivo Normothermic Machine Perfusion

open access: yesArtificial Organs, EarlyView.
This study aimed to investigate the influence of warm ischemic injury on renal vascular responsiveness to vasoactive drugs during normothermic machine perfusion (NMP). We found that the vascular responses to dopamine and norepinephrine could be used as objective indicators to assess kidney viability during NMP.
Isa M. van Tricht   +4 more
wiley   +1 more source

ARR1 and AHP interactions in the multi-step phosphorelay system

open access: yesFrontiers in Plant Science
Plants use multi-step phosphorelay (MSP) systems in response to exogenous and endogenous stimuli. Cytokinin and ethylene are among the factors that engage MSP signaling cascades but examples independent of phytohormones also exist.
Linh H. Tran, Milosz Ruszkowski
doaj   +1 more source

The return of metabolism: biochemistry and physiology of glycolysis

open access: yesBiological Reviews, EarlyView.
ABSTRACT Glycolysis is a fundamental metabolic pathway central to the bioenergetics and physiology of virtually all living organisms. In this comprehensive review, we explore the intricate biochemical principles and evolutionary origins of glycolytic pathways, from the classical Embden–Meyerhof–Parnas (EMP) pathway in humans to various prokaryotic and ...
Nana‐Maria Grüning   +19 more
wiley   +1 more source

Home - About - Disclaimer - Privacy