Role of the PAS2 domain of the NifL regulatory protein in redox signal transduction [PDF]
EThOS - Electronic Theses Online ServiceGBUnited ...
Slavny, Peter
core
Functional characterization of the diatom cyclin-dependent kinase A2 as a mitotic regulator reveals plant-like properties in a non-green lineage [PDF]
Background: Cyclin-dependent kinases (CDKs) are crucial regulators of cell cycle progression in eukaryotes. The diatom CDKA2 was originally assigned to the classical A-type CDKs, but its cell cycle phase-specific transcription at the G2-to-M phase ...
Bowler, Chris+4 more
core +2 more sources
Photo‐controlled Release of Urea Enables the Detection of Urea‐Urease Intermediates by cryo‐FTIR
Caged compounds are a valuable tool to photocontrol the release of enzymatic substrates in a reaction. For example, caged urea molecules were proposed to control urea delivery to urease reactions and aid the determination of the catalytic mechanism of this enzyme.
Caterina Netto+7 more
wiley +1 more source
Reaction Engineering and Comparison of Electroenzymatic and Enzymatic ATP Regeneration Systems [PDF]
Adenosine-5'-triphosphate (ATP) plays a crucial role in many biocatalytic reactions and its regeneration can influence the performance of a related enzymatic reaction significantly. Here, we established an electrochemically coupled ATP regeneration by pyruvate oxidase and acetate kinase (ACK) for the phosphorylation of mevalonate catalyzed by ...
arxiv
The alphaproteobacterial general stress response is governed by a conserved partner-switching mechanism that is triggered by phosphorylation of the response regulator PhyR.
C. Lori+3 more
doaj +1 more source
Studies on the release of neutrophil extracellular traps and IFN-γ as part of the innate immune response to Aspergillus fumigatus and on the fungal stress response via the hybrid sensor kinase TcsC [PDF]
Aspergillus fumigatus is a saprophytic mold that naturally inhabits the soil. Asexual reproduction yields hardy conidia that circulate in the air and are inhaled daily by humans.
McCormick, Allison
core
Spatial tethering of kinases to their substrates relaxes evolutionary constraints on specificity [PDF]
Signal transduction proteins are often multi-domain proteins that arose through the fusion of previously independent proteins. How such a change in the spatial arrangement of proteins impacts their evolution and the selective pressures acting on ...
Ashenberg, Orr+6 more
core +1 more source
The AMP‐induced mutant Staphylococcus aureus strain nzR showed increased resistance, five gene mutations, and decreased surface anion levels. AMPs affect the NDH‐2 protein encoded by ndh gene inhibiting the growth of S. aureus. The deletion of the ndh gene promotes the development of AMPs resistance.
Lingyu Xiao+12 more
wiley +1 more source
The response to cationic antimicrobial peptides (CAMPs) in Staphylococcus aureus relies on a two-component system (TCS), GraSR, an auxiliary protein GraX and an ATP-binding cassette (ABC) transporter, VraF/G.
Uzma Muzamal+3 more
doaj +1 more source
APLF (C2orf13) is a novel human protein involved in the cellular response to chromosomal DNA strand breaks [PDF]
Aprataxin and polynucleotide kinase (PNK) are DNA end processing factors that are recruited into the DNA single- and double-strand break repair machinery through phosphorylation-specific interactions with XRCC1 and XRCC4, respectively. These interactions
Caldecott, Keith W+3 more
core +5 more sources